Traditional Chinese medicine combination therapy for patients with steroid-dependent ulcerative colitis: study protocol for a randomized controlled trial

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• 作者：Kai Zheng ; Hong Shen ; Jia Jia ; Yuelin Lu ; Lei Zhu ; Lu Zhang ; Zhaofeng Shen
• 关键词：5 ; aminosalicylic acid ; Azathioprine ; Chinese herbal medicine ; Steroid ; dependent ulcerative colitis ; Study protocol
• 刊名：Trials
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：18
• 期：1
• 全文大小：506KB
• 刊物主题：Medicine/Public Health, general; Biomedicine, general; Statistics for Life Sciences, Medicine, Health Sciences;
• 出版者：BioMed Central
• ISSN：1745-6215
• 卷排序：18

文摘

BackgroundApproximately 20% of patients with ulcerative colitis become steroid dependent. Azathioprine is recommended in steroid-dependent ulcerative colitis, but its side effects limit its use. Chinese herbal medicine has been widely used to treat ulcerative colitis in China. However, its effectiveness in steroid-dependent patients has not been evaluated. This study aims to investigate the efficacy of traditional Chinese medicine combination therapy with 5-aminosalicylic acid in patients with steroid-dependent ulcerative colitis.