Dose optimization in pediatric nuclear medicine

详细信息    查看全文

• 作者：Frederic Fahey ; S. Ted Treves ; Michael Lassmann
• 关键词：Pediatrics ; Dosimetry ; Radiation risk
• 刊名：Clinical and Translational Imaging
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：4
• 期：1
• 页码：5-11
• 全文大小：376 KB
• 参考文献：1.Treves ST (2014) Pediatric nuclear medicine/PET, 4th edn. Springer, New YorkCrossRef
  2.Treves ST, Baker A, Fahey FH, Cao X, Davis RT, Drubach LA et al (2011) Nuclear medicine in the first year of life. J Nucl Med 52:905–925CrossRef PubMed
  3.Lassmann M, Treves ST, EANM SNMMI Paediatric Dosage Harmonization Working Group (2014) Paediatric radiopharmaceutical administration: harmonization of the 2007 EANM paediatric dosage card (version 1.5.2008) and the 2010 North American consensus guidelines. Eur J Nucl Med Mol Imaging 41:1036–1041CrossRef PubMed
  4.Treves ST, Lassmann M, EANM SNMMI Paediatric Dosage Harmonization Working Group (2014) International guidelines for pediatric radiopharmaceutical administered activities. J Nucl Med 55:869–870CrossRef PubMed
  5.Koizumi K, Masaki H, Matsuda H, Uchiyama M, Okuno M, Oguma E et al (2014) Japanese consensus guidelines for pediatric nuclear medicine. Part 1: pediatric radiopharmaceutical administered doses (JSNM pediatric dosage card). Part 2: technical considerations for pediatric nuclear medicine imaging procedures. Ann Nucl Med 28:498–503PubMedCentral CrossRef PubMed
  6.Hsiao EM, Cao X, Zurakowski D, Zukotynski KA, Drubach LA, Grant FD et al (2011) Reduction in radiation dose in mercaptoacetyltriglycerine renography with enhanced planar processing. Radiology 261:907–915CrossRef PubMed
  7.Fahey F, Zukotynski K, Zurakowski D, Markelewicz R, Falone A, Vitello M et al (2014) Beyond current guidelines: reduction in minimum administered radiopharmaceutical activity with preserved diagnostic image quality in pediatric hepatobiliary scintigraphy. Eur J Nucl Med Mol Imaging 41:2346–2353CrossRef PubMed
  8.Sheehy N, Tetrault TA, Zurakowski D, Vija AH, Fahey FH, Treves ST (2009) Pediatric 99mTc-DMSA SPECT performed by using iterative reconstruction with isotropic resolution recovery: improved image quality and reduced radiopharmaceutical activity. Radiology 251:511–516CrossRef PubMed
  9.Stansfield EC, Sheehy N, Zurakowski D, Vija AH, Fahey FH, Treves ST (2010) Pediatric 99mTc-MDP bone SPECT with ordered subset expectation maximization iterative reconstruction with isotropic 3D resolution recovery. Radiology 257:793–801CrossRef PubMed
  10.Bolch WE, Eckerman KF, Sgouros G, Thomas SR (2009) MIRD pamphlet no. 21: a generalized schema for radiopharmaceutical dosimetry–standardization of nomenclature. J Nucl Med 50:477–484CrossRef PubMed
  11.Ozasa K, Shimizu Y, Suyama A, Kasagi F, Soda M, Grant EJ et al (2012) Studies of the mortality of atomic bomb survivors, report 14, 1950–2003: an overview of cancer and noncancer diseases. Radiat Res 177:229–243CrossRef PubMed
  12.Holm LE, Wiklund KE, Lundell GE, Bergman NA, Bjelkengren G, Cederquist ES et al (1988) Thyroid cancer after diagnostic doses of iodine-131: a retrospective cohort study. J Natl Cancer Inst 80:1132–1138CrossRef PubMed
  13.Hall P, Mattsson A, Boice JD Jr (1996) Thyroid cancer after diagnostic administration of iodine-131. Radiat Res 145:86–92CrossRef PubMed
  14.Dickman PW, Holm LE, Lundell G, Boice JD Jr, Hall P (2003) Thyroid cancer risk after thyroid examination with 131I: a population-based cohort study in Sweden. Int J Cancer 106:580–587CrossRef PubMed
  15.Hahn K, Schnell-Inderst P, Grosche B, Holm LE (2001) Thyroid cancer after diagnostic administration of iodine-131 in childhood. Radiat Res 156:61–70CrossRef PubMed
  16.Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation (2006) National research council, health risks from exposure to low levels of ionizing radiation: BEIR VII phase 2. The National Academies Press, Washington DC
  17.United Nations scientific committee on the effects of atomic radiation (2013) Sources, effects and risks of ionizing radiation. Vol II, scientific annex B: effects of radiation exposure of children. United Nations Publications, New York E.14.IX.2
  18.Piepsz A, Hahn K, Roca I, Ciofetta G, Toth G, Gordon I et al (1990) A radiopharmaceuticals schedule for imaging in paediatrics. Paediatric task group european association nuclear medicine. Eur J Nucl Med 17:127–129CrossRef PubMed
  19.Lassmann M, Biassoni L, Monsieurs M, Franzius C, Jacobs F, Dosimetry E et al (2007) The new EANM paediatric dosage card. Eur J Nucl Med Mol Imaging 34:796–798CrossRef PubMed
  20.Jacobs F, Thierens H, Piepsz A, Bacher K, Van de Wiele C, Ham H et al (2005) Optimised tracer-dependent dosage cards to obtain weight-independent effective doses. Eur J Nucl Med Mol Imaging 32:581–588CrossRef PubMed
  21.Lassmann M, Biassoni L, Monsieurs M, Franzius C (2008) The new EANM paediatric dosage card: additional notes with respect to F-18. Eur J Nucl Med Mol Imaging 35:1666–1668CrossRef PubMed
  22.Treves ST, Davis RT, Fahey FH (2008) Administered radiopharmaceutical doses in children: a survey of 13 pediatric hospitals in North America. J Nucl Med 49:1024–1027CrossRef PubMed
  23.Gelfand MJ, Parisi MT, Treves ST, Pediatric Nuclear Medicine Dose Reduction Workgroup (2011) Pediatric radiopharmaceutical administered doses: 2010 North American consensus guidelines. J Nucl Med 52:318–322CrossRef PubMed
  24.Treves ST, Parisi MT, Gelfand MJ (2011) Pediatric radiopharmaceutical doses: new guidelines. Radiology 261:347–349CrossRef PubMed
  25.Fahey FH, Ziniel SI, Manion D, Treves ST (2015) Effects of Image gently and the North American guidelines: administered activities in children at 13 North American pediatric hospitals. J Nucl Med 56:962–967CrossRef PubMed
  26.Fahey FH, Bom HH, Chiti A, Choi YY, Huang G, Lassmann M et al (2015) Standardization of administered activities in pediatric nuclear medicine: a report of the first nuclear medicine global initiative project, part 1-statement of the issue and a review of available resources. J Nucl Med 56:646–651CrossRef PubMed
  
• 作者单位：Frederic Fahey (1) (2)
  S. Ted Treves (2) (3)
  Michael Lassmann (4)
  
  1. Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Boston Children’s Hospital, Boston, MA, USA
  2. Department of Radiology, Harvard Medical School, Boston, MA, USA
  3. Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women’s Hospital, Boston, MA, USA
  4. Department of Nuclear Medicine, University Hospital Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany
  
• 刊物主题：Nuclear Medicine; Imaging / Radiology; Diagnostic Radiology; Medical and Radiation Physics; Interventional Radiology; Radiotherapy;
• 出版者：Springer Milan
• ISSN：2281-7565

文摘

In 2014, the European Association of Nuclear Medicine (EANM) and the Society of Nuclear Medicine and Molecular Imaging developed consensus guidelines based on the harmonization of the 2007 EANM pediatric dosage card and the 2010 North American consensus guidelines. The Japanese Society of Nuclear Medicine also published guidelines of the administered activities in children in 2014. In 2015, the Nuclear Medicine Global Initiative (NMGI) reviewed the available resources for standardization of administered activities in pediatric nuclear medicine world-wide. In the present work, we review the impact that instrumentation, image processing, and tomographic reconstruction can have on dose optimization of nuclear medicine procedures in children. We also reviewed the historical development and rationale for the existing guidelines and the major shortcomings of the available data for pediatric nuclear medicine. In addition, an overview will be given on the current understanding of the carcinogenic risk of radiation related to the administration of radiopharmaceuticals in children. The application of dosimetric models in children will be discussed including a list of pertinent educational and reference resources. An evaluation of the current practice of pediatric nuclear medicine throughout the world is described, specifically with regard to administered activities as determined by an international survey of nuclear medicine clinics and centers, as reported by the NMGI. Keywords Pediatrics Dosimetry Radiation risk