The LDL/HDL ratio and atherosclerosis in ankylosing spondylitis

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• 作者：Dr. A. Kucuk ; A. Uğur Uslu ; A. Icli ; E. Cure ; S. Arslan…
• 关键词：Dyslipidemias ; Atherosclerosis ; Ankylosing spondylitis ; Ischemia ; modified albumin ; Oxidative Stress
• 刊名：Zeitschrift für Rheumatologie
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：76
• 期：1
• 页码：58-63
• 全文大小：
• 刊物主题：Internal Medicine; Rheumatology;
• 出版者：Springer Medizin
• ISSN：1435-1250
• 卷排序：76

文摘

ObjectivesIn ankylosing spondylitis (AS) patients, cardiac and vascular involvement may manifest as atherosclerosis and coronary artery disease. Systemic inflammation, oxidative stress, increased low-density lipoprotein (LDL) cholesterol and decreased high-density lipoprotein (HDL) cholesterol constitute a significant risk for atherosclerosis. This study investigated the relationship between carotid intima–media thickness (CIMT), LDL/HDL ratio, total oxidant status (TOS; an indicator of oxidative stress) and ischemic modified albumin (IMA; an ischemic marker in AS patients).