U-shaped relationship between early blood glucose and mortality in critically ill children

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• 作者：Yanhong Li ; Zhenjiang Bai ; Mengxia Li ; Xueqin Wang ; Jian Pan…
• 关键词：Critically ill children ; Glucose ; Hyperglycemia ; Hypoglycemia ; Intensive care ; Mortality ; Pediatric ; Pediatric risk of mortality III
• 刊名：BMC Pediatrics
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：15
• 期：1
• 全文大小：663 KB
• 刊物主题：Pediatrics; Internal Medicine;
• 出版者：BioMed Central
• ISSN：1471-2431

文摘

Background The aims of this study are to evaluate the relationship between early blood glucose concentrations and mortality and to define a ‘safe range’ of blood glucose concentrations during the first 24 h after pediatric intensive care unit (PICU) admission with the lowest risk of mortality. We further determine whether associations exist between PICU mortality and early hyperglycemia and hypoglycemia occurring within 24 h of PICU admission, even after adjusting for illness severity assessed by the pediatric risk of mortality III (PRISM III) score.