摘要
噬菌体是一种能够裂解并杀死细菌的病毒,目前其作为鉴定细菌工具、应用于细菌分型及研发新型抗菌生物制剂等已成为研究热点。在肌尾噬菌体科中的T4类噬菌体属是现代遗传学和分子生物学的主要模型系统,对T4类噬菌体进行深入研究更具重要意义。本文从T4类噬菌体的分类,形态特征,与宿主的作用模式,以及从其应用及生物学意义方面进行综述,以期对T4类噬菌体有更深入了解。
Bacteriophage, defined as a virus that can disrupt and kill bacteria, has become a research hotpot currently by applying into bacteria identification techniques, bacterial typing and also the research of the new type of antimicrobial-biological preparations. New phages are usually found in the special places full of bacterial communities, such as soil, aquatic habitats, animal intestines, etc. A specific bacteriophage family that recognized as Myoviridae has been studied thoroughly by many researchers. T4-like phage, usually characterized as long polyhedral head and retractable tail is one of the Myoviridae. T4-like phage has been utilized as the main modeling system in the field of modern genetics and molecular biology, leading a research significance by further lucubrating it. In this particular research, the classification and morphological characteristics of T4-like phage, the interaction mechanism with its hosts and its biological significance are summarized for the purpose of a better and deeper understanding of it.
引文
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