摘要
目的观察评价胺碘酮联合利多卡因在急性心梗伴室性心律失常中的临床疗效。方法采用回顾性分析,方便收集2014年1月—2018年2月该医院收治的急性心梗伴室性心律失常(无房颤致死性心律失常)患者入组,单纯的利多卡因治疗34例,纳入对照组,使用胺碘酮联合利多卡因42例,纳入观察组。对比疗效指标。结果观察组消失率57.1%、控制率35.7%、无效率7.1%,对照组23.5%、47.1%、32.4%,观察组复发率16.7%、严重并发症发生率16.7%低于对照组32.4%、44.1%,差异有统计学意义(χ2/Uc=3.287、7.946、6.884,P=0.001、0.005、0.009<0.05)。观察组治疗后QTd(21.5±8.4)ms低于治疗前(34.1±12.5)ms、对照组(28.5±14.6)ms,差异有统计学意义(t=5.422、2.620,P=0.000、0.011<0.05)。结论胺碘酮联合利多卡因治疗急性心梗伴非致死性室性心律失常疗效肯定。
Objective To evaluate the clinical efficacy of amiodarone combined with lidocaine in acute myocardial infarction with ventricular arrhythmia. Methods A retrospective analysis was performed to convenient collect patients with acute myocardial infarction and ventricular arrhythmia(no atrial fibrillation arrhythmia) admitted to the hospital from January2014 to February 2018. 34 patients were treated with lidocaine alone. In the control group, 42 patients with amiodarone plus lidocaine were included in the observation group. Compare efficacy indicators of the two groups. Results The disappearance rate of the observation group was 57.1%, the control rate was 35.7%, the inefficiency was 7.1%, the control group was 23.5%, 47.1%, 32.4%. The recurrence rate of the observation group was 16.7%, the incidence of serious complications was 16.7%, and the control group was 32.4%. 44.1%, the difference was statistically significant(χ2/Uc=3.287, 7.946, 6.884,P=0.001, 0.005, 0.009<0.05). The QTd(21.5±8.4) ms in the observation group was lower than that before treatment(34.1±12.5) ms and the control group(28.5±14.6) ms. The difference was statistically significant(t=5.422, 2.620, P=0.000, 0.011<0.05). Conclusion Amiodarone combined with lidocaine is effective in the treatment of acute myocardial infarction with non-fatal ventricular arrhythmia.
引文
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