摘要
目的:探讨不停跳搭桥联合新型二尖瓣成形术治疗轻-中度缺血性二尖瓣反流患者的临床效果。方法:选取2016年1月至2017年12月我院收治的轻-中度缺血性二尖瓣反流患者80例作为研究对象,将患者随机分为对照组(n=40)和研究组(n=40)两组。对照组患者行不停跳搭桥手术治疗,研究组患者行不停跳搭桥手术联合新型二尖瓣成形术治疗。对比两组患者手术后1年左心室的舒张、收缩末的内径及内径差、二尖瓣反流程度、心功能分级情况以及两组患者围术期并发症的发生情况。结果:术前两组患者左心室的舒张、收缩末的内径差异无统计学意义(P>0.05);术后1年研究组患者左心室的舒张、收缩末的内径小于对照组(P<0.05);术前两组患者的二尖瓣反流程度及心功能分级情况差异均无统计学意义(P>0.05),术后1年研究组患者的二尖瓣反流程度低于对照组(P<0.05),心功能分级情况优于对照组(P<0.05);研究组患者围术期并发症发生率低于对照组(P<0.05)。结论:对轻-中度缺血性二尖瓣反流患者使用不停跳搭桥联合新型二尖瓣成形术进行治疗,可有效提高患者的治疗效果,减小患者左心室舒张、收缩末的内径,降低患者的二尖瓣反流程度并不增加围术期并发症发生率,改善患者的心功能分级情况。
Objective:To explore the clinical effect of the combination of off pump coronary artery bypass grafting and novel mitral valvuloplasty in the treatment of patients with mild and moderate ischemic mitral regurgitation. Methods:80 patients with mild and moderate ischemic mitral regurgitation treated in our hospital from January 2016 to December 2017 were selected as the research object,and randomly divided into two groups,the control group(n=40) and the study group(n=40). The patients in the control group were treated only by off pump coronary artery bypass grafting surgery,while the patients in the study group were treated by combination therapy with the novel mitral valvuloplasty on the basis of the patients in the control group.Before year and after operation, the inner diameter and diameter difference of left ventricle diastole and contractile end, the degree of mitral regurgitation and the cardiac function classification were compared between the two groups.The number of patients with postoperative complications were compared between the two groups. Results:Before surgery, there was no statistic difference in the inner diameter of the left ventricle in the two groups(P>0.05). Year after surgery, the inner diameter of the left ventricle in the study group was leaser than that in the control group(P<0.05). Before surgery, there was no statistic difference in the level of mitral regurgitation and cardiac function classification between the two groups(P>0.05). After surgery, the level of mitral regurgitation in the study group was lower than that in the control group(P<0.05), and the cardiac function classification in the study group was better than that in the control group(P<0.05). The occurence rate of postoperative complications in the study group was lower than that in the control group(P<0.05). Conclusion:The use of off pump coronary artery bypass grafting combined with novel mitral valvuloplasty on patients with mild and moderate ischemic mitral regurgitation, can effectively improve the therapeutic effect of patients,increase the inner diameter of left ventricular at the end of the diastole and systole, reduce the degree of mitral regurgitation in patients, reduce the occurence rate of complication, and improve the patient′s heart function classification.
引文
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