摘要
目的观察针刺联合补脾益肾汤对椎-基底节动脉供血不足性眩晕(脾肾虚损证)患者血脂、中医证候积分和颅底动脉血流动力学的影响。方法患者96例随机分为两组,对照组给予基础治疗,观察组在基础治疗的同时给予针刺联合补脾益肾汤治疗。治疗3周后,观察两组患者的临床疗效、头晕、目眩、肢冷、腰痛、泄泻等中医证候积分,血清总胆固醇(TC)、三酰甘油(TAG)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C),基底动脉(BA)和双侧椎动脉(VA)的血流动力学变化。结果治疗后,观察组总有效率为93.75%,高于对照组的72.92%(P <0.05)。观察组的头晕、目眩、肢冷、腰痛、泄泻等中医证候积分均高于对照组(P <0.05)。观察组的TC、TAG和LDL-C均低于对照组,而HDL-C高于对照组(P <0.05)。观察组患者的BA和VA的收缩期峰值血流速度、平均流速和搏动指数均高于对照组(P <0.05)。结论针刺联合补脾益肾汤对椎-基底节动脉供血不足性眩晕患者具有较好的临床疗效,可改善中医证候积分和血脂指标,降低颅底动脉血流动力学。
Objective: To study the effect of acupuncture combined with Bupi Yishen Decoction(BYD) on blood lipid,TCM syndromes and intracranial and hemodynamics in vertebral-basilar artery insufficiency vertigo(spleen and kidney deficiency). Methods: 96 patients were randomly divided into two groups. The control group was given basic treatment,while the observation group was given acupuncture combined with BYD. After 3 weeks′treatment,TCM syndrome scores,blood lipid index and hemodynamics of BA and VA were observed. Results:After treatment,the total effective rate of the observation group was 93.75%,higher than that of the control group(72.92%)(P < 0.05),as well as TCM syndrome scores(P < 0.05). The levels of TC,TAG and LDL-C in the observation group were lower,and HDL-C was higher than those in the control group(P < 0.05). The peak systolic blood flow velocity,mean velocity and pulsatility index of BA and VA in the observation group were higher than those in the control group(P < 0.05). Conclusion: Acupuncture combined with BYD has good clinical curative effects on vertebral-basilar artery insufficiency vertigo,and can improve TCM syndrome scores and blood lipid index,and reduce the low hemisphere hemodynamics.
引文
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