摘要
目的:观察通督益阳灸法对脑梗死后认知障碍患者认知功能的影响。方法:将57例脑梗死患者随机分为治疗组29例和对照组28例。治疗组采用通督益阳灸配合认知功能训练治疗,对照组仅采用认知功能训练治疗。比较两组治疗前后Barthel指数(modified barthel index,MBI)评分、蒙特利尔认知评价量表(montreal cognitive assessment,MoCA)评分及事件相关电位P300情况。结果:两组治疗后MoCA量表各项评分与同组治疗前比较均有所提高,差异具有统计学意义(P <0. 05)。治疗组治疗后MoCA量表各项评分与对照组比较均有所提高,差异具有统计学意义(P <0. 05)。两组患者治疗后MBI评分与治疗前比较,差异具有统计学意义(P <0. 01);治疗组治疗后MBI评分与对照组比较,差异具有统计学意义(P <0. 05)。两组治疗后P300波幅、潜伏期与同组治疗前比较,差异均具有统计学意义(P <0. 01)。治疗组治疗后P300波幅、潜伏期与对照组比较,波幅升高,潜伏期缩短,差异具有统计学意义(P <0. 05)。P300波幅与MoCA评分呈正相关性,P300潜伏期与MoCA评分呈负相关性。结论:通督益阳灸可改善脑梗死后认知障碍患者的认知功能。
Objective: To observe the effect of Tongdu Yiyang moxibustion on cognitive function of patients with cognitive dysfunction after cerebral infarction. Methods: 7 patients with cerebral infarction were randomly divided into treatment group( 29 cases)and control group( 28 cases). The treatment group was treated with Tongdu Yiyang moxibustion combined with cognitive function training,while the control group was treated with cognitive function training only. The modified barthel index( MBI) score,montreal cognitive assessment( MoCA) score and event-related electric potential P300 were compared before and after treatment. Results: After treatment,the scores of MoCA scale in both groups were improved compared with those before treatment,and the difference was statistically significant( P < 0. 05). After treatment,the scores of MoCA scale in the treatment group were improved compared with those in the control group,and the difference was statistically significant( P < 0. 05). There was significant difference in MBI scores between the two groups before and after treatment( P < 0. 01). After treatment,the MBI scores of the treatment group were significantly different from that of the control group( P < 0. 05). There were significant differences in the amplitude and latency of P300 between the two groups before and after treatment( P < 0. 01). After treatment,the amplitude and latency of P300 in the treatment group were higher and shorter than those in the control group( P < 0. 05). The amplitude of P300 was positively correlated with MoCA score,while the latency of P300 was negatively correlated with MoCA score. Conclusion: Tongdu Yiyang Moxibustion can improve cognitive function of patients with cognitive dysfunction after cerebral infarction.
引文
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