摘要
膝骨关节炎(KOA)是一种主要累及人体膝关节软骨的常见退行性疾病,其发生发展是由多因素相互作用的复杂过程。近年来,细胞因子及其与细胞因子相关的信号通路在KOA的发生、发展的研究中备受关注,并取得了一定的进展。本文将对与KOA的发生有密切关系的炎症因子及信号通路两个方面对膝骨性关节炎的研究进展作一综述。
The knee osteoarthritis(KOA) is a kind of knee joint cartilage degenerative change and irreversible bone arthropathy.The occurrence and development of KOA may result from the reaction of a series of factors.In recent years,it has become the hot issue of cytokines and their signal pathways,especially due to the research of the occurrence and development of KOA.This essay reviews the development of cytokines and signal pathways in KOA.
引文
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