摘要
目的探讨唐山市青年人群2型糖尿病致病的主要危险因素,为城市青年人群制定适宜的糖尿病预防和干预措施提供科学依据。方法采用1∶1匹配病例对照研究方法,选取2016年10月—2017年3月于唐山市开滦总医院健康体检中心进行健康体检的青年体检者为对象。其中,患有2型糖尿病的261例患者为病例组,同期体检的非2型糖尿病青年人261名为对照组。应用一般情况调查表和体检表(体格检查表和实验室检查表)进行调查,采用Logistic回归分析探讨青年人2型糖尿病致病危险因素。结果唐山市青年人群的婚姻状况(OR=0.429)、喜甜食(OR=1.130)、喜荤食(OR=1.344)、体育锻炼情况(OR=0.906)和腰臀比(OR=1.251)是其患2型糖尿病的主要影响因素。结论无配偶、高糖和高脂肪的摄入、肥胖为唐山市青年人群2型糖尿病的危险因素,经常性的体育锻炼可以起到保护作用。
Objective To explore the main risk factors of type 2 diabetes mellitus in young people in Tangshan and provide scientific basis for the formulation of appropriate prevention and intervention measures for young people.Methods The 1∶1 matched case-control study was used.From October 2016 to March 2017,the subjects were selected from the health examination center of Kailuan general hospital of Tangshan.Among them,261 patients with type 2 diabetes were the case group,and the young people without type 2 diabetes who underwent physical examination at the same time were the control group.General information questionnaire and physical examination form(physical examination form and laboratory examination form) were used for the investigation.Logistic regression analysis was used to investigate the risk factors of type 2 diabetes mellitus in young people.Results The marital status(OR=0.429),sweet food(OR=1.130),carnivorous food(OR=1.344),physical exercise(OR=0.906) and waist-to-hip ratio(OR=1.251) were the main influencing factors of type 2 diabetes.Conclusion No spouse,high sugar,high fat intake and obesity are the risk factors for type 2 diabetes in young people,regular physical exercise can play a protective role.
引文
[1] 秦培洁.姜黄素对2型糖尿病模型大鼠及3T3-L1前脂肪细胞PTP1B通路的影响研究[D].北京:北京中医药大学,2014.
[2] Kaiser A,Vollenweider P,Waeber G,et al.Prevalence,awareness and treatment of type2 diabetes mellitus in Switzerland:the colaus study[J].Diadet Med,2012,29(2):190-197.
[3] Yang W,Lu J,Weng J,el al.Prevalence of diabetes among men and women in China[J].N Engl J Med,2010,362(12):1090-1101.
[4] 宫永辉,王旭春,蔡奔,等.低龄2型糖尿病影响因素的病例对照研究[J/OL].中国预防医学杂志,2018,19(10):1-4[2019-02-20].http://kns.cnki.net/kcms/detail/11.4529.R.20181018.1609.006.html.
[5] 赵连利,刘可魂,王永森.沧州市青年2型糖尿病患病率和知晓率调查[J].临床荟萃,2016,31(3):334-335.
[6] 谢坤,张晓庆.住院2型糖尿病合并抑郁症患者生命质量的相关性研究[J].中华疾病控制杂志,2014,18(6):515-517.
[7] 徐慧兰,宋爽,肖水源,等.2型糖尿病危险因素的研究进展[J].中国现代医学杂志,2011,21(15):1872-1876.
[8] 刘梦姣,曾慧.2型糖尿病并发轻度认知功能障碍危险因素研究进展[J].中国老年学杂志,2015,35(13):3776-3779.
[9] Lu Y,Hajifathalian K,Ezzati M,et al.Metabolic mediators of the effects of body-mass index,overweight,and obesity on coronary heart disease and stroke:a pooled analysis of 97 prospective cohorts with 18 million participants[J].Lancet,2014,383(9921):970-983.
[10] 王佳.糖尿病患者家庭功能、希望水平与授权能力的量性与质性研究[D].哈尔滨:黑龙江中医药大学,2013.
[11] 周吉,周芳华,石健,等.南宁市35岁以上2型糖尿病患者血糖控制现状及影响因素分析[J].中华疾病控制杂志,2014,18(9):816-819.
[12] 王超.中国成人超重和肥胖及主要危险因素对糖尿病发病的影响[D].北京:北京协和医学院,2014.
[13] 张璇,肖琛嫦,陈功,等.武汉市成年居民糖尿病患病现状及危险因素分析[J].中国公共卫生,2015,31(12):1594-1596.
[14] 孔宪如,蔡燕,谢菲.增加运动量对新诊断肥胖2型糖尿病患者影响的观察[J].中国糖尿病杂志,2012,20(9):663-666.
[15] 王文芸,朱平光,陈颂芬.象山地区流动人口糖尿病及其相关因素分析[J].中国公共卫生管理,2016,32(2):193-195.
[16] 王慧奇,苑记清.前瞻性应对在青年糖尿病患者健康教育中的应用[J].天津护理,2018,26(2):131-133.
