摘要
目的探讨砂粒体型脑膜瘤(PM)的影像学表现及与相关疾病的鉴别。方法分析1例PM患者的临床表现、影像学表现、病理学特征及文献复习。结果 PM因生长部位不同而临床表现各异,在影像资料完善的情况下,其易与骨瘤造成误诊。结论钙化是PM的主要成分,其特征性影像学表现仍需继续探讨,目前病理特征是诊断PM的金标准。
Objective To study the imaging manifestations and related identification of psammomatous meningioma(PM). Method One case of PM patient was analyzed with clinical features, imaging findings,pathologic characteristics and literature review. Results PM has different clinical manifestations due to different growth sites. Under the condition of perfect imaging data, PM is easy to cause misdiagnosis with bone-derived tumors.Conclusion Calcification is the main component of PM. At present, pathological features are the gold standard for the diagnosis of PM because its characteristic imaging manifestations still need to be further discussed.
引文
[1]Smith JH.Psammoma bodies in cervical smears:sifting the grains of sand[J].Cytopathology,2007,18(3):140-142.
[2]郭翠萍,张雪林,吕晓飞,等.钙化性砂粒体型脑膜瘤的CT与MRI诊断[J].临床放射学杂志,2011,30(1):22-25.
[3]官青,吴毅.砂粒体在甲状腺癌研究中的进展[J].中国癌症杂志,2009,19(8):637-640.
[4]Fadare O,Chacho MS,Parkash V.Psammoma bodies in cervicovaginal smears[J].Adv Anat Pathol,2004,11(5):250-261.
[5]李晓龙,李志辉.浅析砂粒体在人体肿瘤中的形成机理及相关问题[J].河南肿瘤学杂志,2010,17(11):1216-1218.
[6]杨若晨,王长秋,鲁安怀,等.脑膜瘤中砂粒体矿化研究[J].地学前缘,2008,15(6):44-53.
[7]Kubota T,Yamashima T,Hasegawa M,et al.Formation of psammoma bodies in meningocytic whorls:ultrastructural study and analysis of calcified material[J].Acta Neuropathol,1986,70(3-4):262-268.
[8]Han J,Daniel JC,Pappas GD.Expression of type VI collagen in psammoma bodies:immunofluorescence studies on two fresh human meningiomas[J].Acta Cytol,1996,40(2):177-181.
[9]Tunio GM,Hirota S,Nomura S,et al.Possible relation of osteopontin to development of psammoma bodies in human papillary thyroid cancer[J].Arch Pathol Lab Med,1998,122(12):1087-1090.
[10]Raghunath A,Devi B I,Bhat D I,et al.Unusual complications of a benign tumour-our experience with midline posterior fossa epidermoids[J].Br J Neurosurg,2013,27(1):69-73.
[11]Atalay FO,Ozgun G,Tolunay S,et al.Intracranial extra-axial chondroma:a case of report[J].J Nippon Med Sch,2014,81(1):35-39.
[12]赵沁萍.完全钙化型脑膜瘤3例报告并文献分析[J].广西医学,2012;34(11):1582-1583.
[13]刘荣,丁祥华,龚迅,等.钙化性脑膜瘤磁共振T1加权像高信号分析[J],实用医学影像杂志,2017,18(4):302-305
[14]Niiro M,Yatsushiro K,Nakamura K,et al.Natural history of elderly patients with asymptomatic meningiomas[J].J Neurol Neurosurg Psychiatry,2000,68(1):25-28.
[15]Nakasu S,Nakajima M,Matsumura K,et al.Meningioma:proliferating potential and clinicoradiological features[J].Neurosurg,1995,37(6):1049-1055.
[16]Das DK.Psammoma body:a product of dystrophic calcificalion or of a biologically active process that aims at limiting the growth and spread of tumor?[J].Diagn Cytopathol,2009,37(7):534-541.
