摘要
目的:利用Meta分析方法分析补肾活血中药治疗下腰痛的临床疗效。方法:检索电子数据库中国知网数据库、重庆维普中文科技期刊数据库、万方数据库、Pubmed、Embase、Cochrane Library、SinoMed中符合补肾活血中药治疗下腰痛疗效的相关RCT文献,检索时间为建库至2018年7月20日。使用Cochrane协作网推荐的方法评价纳入文献质量,并对纳入研究的测量指标通过Revman 5.3软件进行Meta分析。结果:严格按照纳入标准、排除标准共纳入16篇随机对照试验研究,纳入病例1034例。Meta分析结果显示:单独服用或者加服补肾活血中药组在总有效率[RR=0.31,95%CI(0.23,0.42)]、疼痛减轻程度[RR=-1.29,95%CI(-1.75,-0.82)]、ODI评分[RR=-8.28,95%CI(-12.94,-3.62)]方面,优于其它疗法组;倒漏斗图显示有发表偏倚。结论:补肾活血中药在改善下腰痛疼痛、腰部功能等方面有良好的疗效。
Objective:To evaluate the clinical efficacy of traditional Chinese medicine for Bushen Huoxue in the treatment of low back pain with Meta-analysis. Methods:The relevant RCT literatures in the electronic databases of China Knowledge Network Database,Chongqing Weipu Chinese Science and Technology Journal,WanFang Database,Pubmed,Embase,Cochrane Library and SinoMed were retrieved from July 20,2018. Cochrane collaboration network was used to evaluate the quality of the included literatures,and the measurement indicators were analyzed by Revman 5.3 software. Results:A total of 16 randomized controlled trials and 1034 cases were included according to inclusion criteria and exclusion criteria. Meta-analysis showed that the total effective rate[RR=0.31,95% CI(0.23,0.42)],pain relief degree[RR=-1.29,95% CI(-1.75,0.82)]and ODI score[RR=-8.28,95% CI(-12.94,3.62)]of the treatment group were better than those of the other groups. The chart showed publication bias. Conclusion:Traditional Chinese medicine for Bushen Huoxue has a good effect in improving low back pain and waist function.
引文
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