~(18)F-FDG SPECT/CT显像在食管癌治疗前分期诊断中的应用价值

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英文篇名：Application of ~(18)F-FDG SPECT/CT in the Staging of Esophageal Cancer Before Treatment 作者：叶雪梅 ; 张春燕 ; 章晨 ; 姚丽芳 英文作者：YE Xue-mei,ZHANG Chun-yan,ZHANG Chen,et al.(Zhejiang Cancer Hospital,Treatment and Diagnosis Center of Nuclear Medicine of Zhejiang Province,Zhejiang Key Laboratory of Diagnosis & Treatment Technology on Thoracic Oncology(Lung and Esophagus),Hangzhou 310022,China) 关键词：氟(~18F)-氟代脱氧葡萄糖 ; 体层摄影术 ; 发射型计算机断层扫描 ; 食管肿瘤 ; 淋巴结 英文关键词：18F fluorodeoxyglucose;tomography,emission-computed,single photon;esophageal neoplasms;lymph node 中文刊名：XHON 英文刊名：Journal of Chinese Oncology 机构：浙江省肿瘤医院,浙江省核医学诊治中心,浙江省胸部肿瘤(肺、食管)诊治技术研究重点实验室; 出版日期：2012-10-20 出版单位：肿瘤学杂志 年：2012 期：v.18;No.122 语种：中文; 页：XHON201210015 页数：6 CN：10 ISSN：33-1266/R 分类号：47-52

摘要

[目的]探讨氟(18F)-氟代脱氧葡萄糖(18F-FDG)双探头符合线路断层融合显像(SPECT/CT)在食管癌诊断中的价值。[方法]149例临床疑诊食管癌患者行18F-FDG双探头符合线路SPECT检查,诊断结果与病理检查结果对照。[结果]149例原发肿块定性诊断的灵敏度、特异性、准确率分别为98.6%(139/141)、75.0%(6/8)、96.6%(139/149);253枚可疑转移淋巴结诊断的灵敏度、特异性、准确率分别为94.4%(201/213)、55.0%(22/40)、84.2%(223/253);56例患者的78个远处病灶中,最终67个病灶被确诊为转移,其灵敏度、特异性、准确率分别为97.0%(65/67)、90.9%(10/11)、96.2%(75/78)。[结论]18F-FDG双探头符合线路SPECT/CT在食管癌治疗前诊断分期上具有较高的准确率和灵敏度,为食管癌术前较好的无创性检查方法。
        [Purpose] To explore the clinical value of 18 F-FDG single-photon emission comptuted tomography/computed tomography(SPECT/CT) in the staging of esophageal cancer.[Method]One hundred forty-nine cases with suspected esophageal cancer underwent 18 F-FDG SPECT/CT,and the results were compared with the pathological findings.[Results] Of all the 149 patients,the sensi-tivity,specificity and accuracy of diagnosis of the primary tumors were 98.6%(139/141),75.0%(6/8) and 96.6%(139/149) respectively,and those of the 253 suspected metastatic lymph nodes were 94.4%(201/213),55.0%(22/40) and 84.2%(223/253) respectively.Seventy-eight distant lesions were detected in 56 patients,and finally 67 lesions were diagnosed as metastasis.The sensi-tivity,specificity and accuracy of metastasis were 97.0%(65/67),90.9%(10/11) and 96.2%(75/78) respectively.[Conclusion] 18 F-FDG SPECT/CT has high accuracy and sensitivity in the stag-ing of esophageal cancer before treatment,and is a useful and noninvasive method.

引文

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