摘要
目的分析血清血浆降钙素原(PCT)和C-反应蛋白(CRP)对肝硬化腹水自发性细菌性腹膜炎(spontaneous bacterial peritonitis, SBP)的诊断参考价值。方法选取2015年3月-2018年3月于本院就诊的肝硬化合并感染性腹水的78例患者为研究对象,根据其是否出现SBP分为SBP组和非SBP组,比较2组患者的临床资料,构建受试者工作特征(receiver operating characteristic, ROC)曲线,评价PCT和CRP的诊断敏感度和特异性。结果非SBP组的PCT和CRP水平均显著低于SBP组(P<0.05)。联合诊断的ROC曲线下面积显著高于单独的PCT和CRP检测水平。结论当患者的PCT及CRP升高时其对肝硬化腹水SBP具有较好的参考价值,值得临床推广使用。
Objective To analyze the diagnostic value of serum plasma procalcitonin(PCT) and C-reactive protein(CRP) in the diagnosis of spontaneous bacterial peritonitis(SBP) in cirrhotic ascites. Methods A total of 78 patients with cirrhosis complicated with ascites who were admitted to our hospital during March 2015-March 2018 were selected as the study subjects. According to whether they had SBP, the patients were divided into SBP group and non-SBP group. The patient's clinical data, the receiver operating characteristic(ROC) curve, and the diagnostic sensitivity and specificity of PCT and CRP were evaluated. Results The PCT and CRP levels in the non-SBP group were significantly lower than those in the SBP group(P<0.05). The ROC curve area for combined diagnosis was significantly higher than that for PCT and CRP alone. Conclusion When the patient's PCT and CRP are elevated, it has a good reference value for cirrhotic ascites SBP and is worthy of clinical application.
引文
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