摘要
目的探讨重复经颅磁刺激(r TMS)对严重意识障碍(DOC)患者的临床及神经影像学变化。方法将2017年10月至2018年12月在广西壮族自治区江滨医院神经康复科治疗的24例严重DOC患者随机分为实验组和对照组,每组各12例。对照组给予常规康复,实验组给予r TMS治疗。比较两组治疗前后改良昏迷恢复量表(CRS-R)评分,并行脑功能核磁共振检查,计算局部一致性(Re Ho)值。结果实验组治疗后CRS-R评分较前显著升高组间比较差异有统计学意义(P <0.05),顶叶、前额叶Re Ho值升高。结论 rTMS治疗后严重DOC患者意识水平评分提高;治疗后顶叶、前额叶神经元活动的一致性和同步性程度或可提高。
引文
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