摘要
目的探讨肌注绒毛膜促性腺激素(HCG)联合穴位埋线治疗卵泡未破裂黄素化综合征的效果。方法选择2017年5月～2018年5月于广东省佛山市南海区妇幼保健院就诊的卵泡未破裂黄素化综合征患者100例,按随机数字表法分为对照组和治疗组,每组各50例。对照组给予肌注HCG针,治疗组在对照组基础上进行穴位埋线治疗。治疗前后分别检测血清黄体生成素(LH)、孕酮(P)、雌二醇(E_2)水平,血常规,肝肾功能。结果两组患者平均治疗周期与排卵周期比较,差异无统计学意义(P> 0.05)。治疗组妊娠率、排卵率高于对照组,差异有统计学意义(P <0.05)。治疗后,两组患者血清P、LH水平与治疗前比较均升高,且治疗组血清P、LH、E_2水平均高于对照组,差异有统计学意义(P <0.05)。肌注HCG前,两组患者血清P比较,差异无统计学意义(P> 0.05),治疗组肌注HCG前内膜厚于对照组,差异有统计学意义(P <0.05);肌注7 d后,两组患者血清P均高于肌注HCG前,且治疗组高于对照组,差异有统计学意义(P <0.05);肌注7 d后,两组患者内膜均厚于肌注HCG前,且治疗组内膜厚于对照组,差异有统计学意义(P <0.05)。结论穴位埋线配合肌注HCG针治疗可使卵泡未破裂黄素化综合征患者LH水平上升,增加排卵率,排卵后P水平升高,内膜增厚,从而提高受孕率。
Objective To investigate the clinical effect of intramuscular injection of cashmere combined with acupoint catgut embedding therapy on luteinizing unruptured follicle syndrome. Methods A total of 100 cases of luteinizing unruptured follicle syndrome patients were selected from May 2017 to May 2018 in Foshan Nanhai District Maternal and Child Health Hospital of Guangdong Province, they were divided into control group and treatment group by random number table method, with 50 cases in each group. The control group received intramuscular injection of human chorionic gonadotropin(HCG) needle, and the treatment group was treated with catgut implantation at acupoint on the basis of the control group. Serum luteinizing hormone(LH), progesterone(P) and estrogenic hormone(E_2) levels, blood routine, liver and kidney function were assayed before and after treatment. Results There was no significant difference in the average treatment cycle and ovulation cycle between the two groups(P > 0.05). The pregnancy rate and ovulation rate in the treatment group were higher than those in the control group(P < 0.05). After treatment, the serum P and LH levels of the two groups were higher than before treatment, and the serum P, LH and E_2 levels of the treatment group were higher than those of the control group, the differences were statistically significant(P < 0.05). Before intramuscular injection of HCG, there was no significant difference in serum P between the two groups(P > 0.05). The intima thickness before intramuscular injection of HCG in the treatment group was thicker than that in the control group(P <0.05). Seven days after intramuscular injection, serum P level in the two groups were higher than those before intramuscular injection of HCG, and the treatment group was higher than that in the control group(P < 0.05). After 7 days of intramuscular injection, the intima thickness of both groups were thicker than those before intramuscular injection of HCG, and the intima thickness of the treatment group was thicker than that of the control group, the difference was statistically significant(P < 0.05). Conclusion Acupoint catgut embedding plus intramuscular injection HCG needle can promote ovulation by elevated serum LH levels, progesterone increase right and endometrial thickness become suitable after ovulation, thereby improving pregnancy rates in the patients with polycystic ovarian syndrome.
引文
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