青春期多囊卵巢综合征的诊治进展
详细信息    查看全文 | 推荐本文 |
  • 英文篇名:Progress of Diagnosis and Treatment of Adolescent Polycystic Ovary Syndrome
  • 作者:陈欢 ; 洛若愚
  • 英文作者:CHEN Huan;LUO Ruoyu;Department One of Gynecology,Renmin Hospital of Wuhan University;
  • 关键词:多囊卵巢综合征 ; 青春期多囊卵巢综合征 ; 血清雄激素 ; 抗苗勒管激素
  • 英文关键词:Polycystic ovary syndrome;;Adolescent polycystic ovary syndrome;;Serum androgen;;Anti-müllerian hormone
  • 中文刊名:YXZS
  • 英文刊名:Medical Recapitulate
  • 机构:武汉大学人民医院妇一科;
  • 出版日期:2019-02-01 15:22
  • 出版单位:医学综述
  • 年:2019
  • 期:v.25
  • 语种:中文;
  • 页:YXZS201903027
  • 页数:6
  • CN:03
  • ISSN:11-3553/R
  • 分类号:140-145
摘要
多囊卵巢综合征(PCOS)是育龄期女性最常见的内分泌与代谢紊乱性疾病之一。PCOS多在青春期起病,给许多青春期女性的生理及精神造成伤害。近年来,青春期PCOS的患病率逐渐升高,发病年龄逐渐提前,患者多因月经稀发、不规则阴道出血、多毛以及肥胖等原因就诊,女性青春期的许多生理变化类似于青春期PCOS的临床表现,导致青春期PCOS诊断困难。青春期正处于女性性腺发育阶段,各器官系统功能尚处于发育完善阶段,故需要积极干预青春期PCOS,目前尚无统一标准的诊疗方案,但应谨慎使用药物。
        Polycystic ovary syndrome( PCOS) is one of the most common endocrine and metabolic disorders in women of childbearing age. PCOS often onsets in puberty,which causes physical and mental harm to many adolescent women. In recent years,the prevalence of adolescent PCOS has gradually increased,the age of onset is gradually getting younger. The patients go to see a doctor because of oligomenorrhea,irregular vaginal bleeding,hairy and obesity,because many physiological changes in female adolescence are similar to the clinical manifestations of adolescent PCOS,resulting in difficult diagnosis of adolescent PCOS. Adolescence is at the stage of female gonad development,and the organ system function is still in development,so active intervention is needed for the adolescent PCOS,and caution should be taken for drug usage,since there is no unified standard of diagnosis and treatment program yet.
引文
[1]刘颖华,侯丽辉,李妍,等.青春期多囊卵巢综合征治疗研究进展[J].生殖与避孕,2015,35(6):420-424.
    [2]巩纯秀,李豫川,吴迪.多囊卵巢综合征发病机制研究及青春期多囊卵巢综合征研究进展[J].中华儿科杂志,2012,50(6):425-428.
    [3]王丽娜,乔杰,李美芝.青春期多囊卵巢综合征临床特点分析[J].北京大学学报(医学版),2007,39(2):208-209.
    [4]赵楠楠,崔毓桂,刘嘉茵.青春期多囊卵巢综合征的诊疗进展[J].国际生殖健康/计划生育杂志,2013,32(3):198-202.
    [5]Witchel SF,Oberfield S,Rosenfield RL,et al. The Diagnosis of Polycystic Ovary Syndrome during Adolescence[J]. Hor Res Paediatr,2015,83(6):376-389.
    [6]全国卫生产业企业管理协会妇幼健康产业分会生殖内分泌学组.青春期多囊卵巢综合征诊治共识[J].生殖医学杂志,2016,25(9):767-770.
    [7]Sultan C,Paris F. Clinical expression of polycystic ovary syndrome in adolescent girls[J]. Fertil Steril,2006,86 Suppl 1:S6.
    [8]崔荔群.探讨青春期多囊卵巢综合征与功血的相关性[J].中国继续医学教育,2017,9(21):98-99.
    [9]Rosenfield RL. The Diagnosis of Polycystic Ovary Syndrome in Adolescents[J]. Pediatrics,2015,136(6):1154-1165.
    [10]洪宇,杨冬梓.中国大陆青春期多囊卵巢综合征特征与诊治[J].中国实用妇科与产科杂志,2013,29(11):852-856.
    [11]李慕白,刘畅,侯丽辉.青春期多囊卵巢综合征诊断标准的现状分析[J].国际生殖健康/计划生育杂志,2011,30(3):255-261.
    [12]徐芳,马明,侯丽辉.青春期多囊卵巢综合征的诊断[J].世界中西医结合杂志,2013,8(4):410-413.
    [13]吴朝霞,吴才标,周运专,等.多普勒超声在多囊卵巢综合征中的影像学特征及诊断价值[J].中国性科学,2017,26(2):25-27.
    [14]周春艳,韩秋花.经阴道彩色多普勒在多囊卵巢综合征诊断中的应用价值[J].吉林医学,2011,32(28):5905-5906.
    [15]倪暾,农媛冰.经阴道超声对多囊卵巢综合征和多卵泡综合征的鉴别诊断价值[J].吉林医学,2011,32(31):6534-6535.
    [16]Rackow BW,Vanden Brink H,Hammers L,et al. Ovarian Morphology by Transabdominal Ultrasound Correlates With Reproductive and Metabolic Disturbance in Adolescents With PCOS[J]. J Adolesc Health,2018,62(3):288-293.
    [17]邓霭静.青春期多囊卵巢综合征早期鉴别的研究进展[J].中国保健营养,2017,27(18):71-72.
    [18]Merino PM,Codner E,Cassorla F. A rational approach to the diagnosis of polycystic ovarian syndrome during adolescence[J].Arq Bras Endocrinol Metabol,2011,55(8):590-598.
    [19]Witchel SF,Roumimper H,Oberfield S. Polycystic Ovary Syndrome in Adolescents[J]. Endocrinol Metab Clin North Am,2016,45(2):329-344.
    [20]张念,李留霞,张颖,等.各项雄激素指标用于诊断多囊卵巢综合征的临床意义[J].现代妇产科进展,2017,26(3):179-182.
    [21]李岩,王国纬,梁琛,等.游离睾酮指数对诊断多囊卵巢综合征的临床研究[J].山西医药杂志,2017,46(9):1051-1053.
    [22]贺侠琴.抗缪勒管激素在多囊卵巢综合征中的诊断意义的研究[J].国际检验医学杂志,2017,38(16):2258-2261.
    [23]Diamandis EP,Yu H. New biological functions of prostate-specific antigen?[J]. J Clin Endocrinol Metab,1995,80(5):1515-1517.
    [24]Vural B,?zkan S,Bodur H. Is prostate-specific antigen a potential new marker of androgen excess in polycystic ovary syndrome?[J].J Obstet Gynaecol Res,2007,33(2):166-173.
    [25]Bahceci M,Bilge M,Tuzcu S,et al. Serum prostate specific antigen levels in women with polycystic ovary syndrome and the effect of flutamide+desogesogestrel/ethinyl estradiol combination[J].J Endocrinol Invest,2004,27(4):353-356.
    [26]叶鹏,郑莉,魏东,等.血清前列腺特异性抗原在多囊卵巢综合征患者中的水平变化及其诊断价值[J].山东医药,2017,57(13):52-54.
    [27]Bili E,Dampala K,Iakovou I,et al. The combination of ovarian volume and outline has better diagnostic accuracy than prostatespecific antigen(PSA)concentrations in women with polycystic ovarian syndrome(PCOs)[J]. Eur J Obstet Gynecol Reprod Biol,2014,179(2):32-35.
    [28]张冬迅,赵新翠,胡艳云.青春期多囊卵巢综合征胰岛素抵抗与非胰岛素抵抗患者生殖内分泌指标差异性研究[J].临床合理用药杂志,2016,9(32):121-122.
    [29]陈晓莉,洪宇,杨冬梓.青春期多囊卵巢综合征的诊治[J].国际生殖健康/计划生育杂志,2013,26(5):330-334.
    [30]Chen X,Yang D,Li L,et al. Abnormal glucose tolerance in Chinese women with polycystic ovary syndrome[J]. Hum Reprod,2006,21(8):2027-2032.
    [31]杨冬梓,陈晓莉.如何掌握青春期多囊卵巢综合征的诊断[J].国际生殖健康/计划生育杂志,2011,30(5):352-354.
    [32]张春兰,侯丽辉,李妍,等.青春期多囊卵巢综合征的高危筛查和治疗[J].中国中医基础医学杂志,2013,19(10):1158.
    [33]Javed A,Chelvakumar G,Bonny AE. Polycystic ovary syndrome in adolescents[J]. Curr Opin Obstet Gynecol,2016,28(5):373-380.
    [34]Nidhi R,Padmalatha V,Nagarathna R,et al. Effects of a holistic yoga program on endocrine parameters in adolescents with polycystic ovarian syndrome:A randomized controlled trial[J]. J Altern Complement Med,2013,19(2):153-160.
    [35]Nidhi R,Padmalatha V,Nagarathna R,et al. Effect of a yoga program on glucose metabolism and blood lipid levels in adolescent girls with polycystic ovary syndrome[J]. Int J Gynaecol Obstet,2012,118(1):37-41.
    [36]Wong JM,Gallagher M,Gooding H,et al. A randomized pilot study of dietary treatments for polycystic ovary syndrome in adolescents[J]. Pediatr Obes,2016,11(3):210-220.
    [37]Agapova SE,Cameo T,Sopher AB,et al. Diagnosis and challenges of polycystic ovary syndrome in adolescence[J]. Semin Reprod Med,2014,32(3):194-201.
    [38]Lanzo E,Monge M,Trent M. Diagnosis and Management of Polycystic Ovary Syndrome in Adolescent Girls[J]. Pediatr Ann,2015,44(9):e223-230.
    [39]Spritzer PM,Motta AB. Adolescence and polycystic ovary syndrome:Current concepts on diagnosis and treatment[J]. Int J Clin Pract,2015,69(11):1236-1246.
    [40]陆杉,倪运萍,冯妙芙,等.不同干预措施对青春期肥胖型多囊卵巢综合征患者糖脂代谢的影响[J].中国预防医学杂志,2015,16(3):205-208.
    [41]陈红霞.炔雌醇环丙孕酮联合二甲双胍治疗青春期多囊卵巢综合征的临床效果观察[J].现代实用医学,2017,29(1):80-81.
    [42]于淼淼,张艳梅,党洁明,等.雌激素与二甲双胍联合治疗青春期多囊卵巢综合征的临床疗效分析[J].中国性科学,2017,26(4):38-41.
    [43]Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and longterm health risks related to polycystic ovary syndrome[J]. Fertil Steril,2004,81(1):19-25.
    [44]Hecht Baldauff N,Arslanian S. Optimal management of polycystic ovary syndrome in adolescence[J]. Arch Dis Child,2015,100(11):1076-1083.
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.