Real case of primitive embryonal duodenal carcinoma in a young man

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英文篇名：Real case of primitive embryonal duodenal carcinoma in a young man 作者：Julien ; Barbieux ; Riccardo ; Memeo ; Vito ; De ; Blasi ; Sebastian ; Suciu ; Vanina ; Faucher ; Gerlinde ; Averous ; Catherine ; Roy ; Jacques ; Marescaux ; Didier ; Mutter ; Patrick ; Pessaux 英文作者：Julien Barbieux;Riccardo Memeo;Vito De Blasi;Sebastian Suciu;Vanina Faucher;Gerlinde Averous;Catherine Roy;Jacques Marescaux;Didier Mutter;Patrick Pessaux;Hepato-Biliary and Pancreatic Surgical Unit, IRCAD-IHU, University of Strasbourg, Place de l'H?pital;Department of Gastroenterology,NHC,University of Strasbourg, Place de l'H?pital;Department of Radiology,NHC, University of Strasbourg, Place de l'H?pital;Department of Pathology, NHC,University of Strasbourg,Place de l'H?pital; 英文关键词：Embryonal carcinoma;;Germ cell tumour;;Duodenum;;Young male;;Pancreaticoduodenectomy 中文刊名：ZXXY 英文刊名：世界胃肠病学杂志(英文版) 机构：Hepato-Biliary and Pancreatic Surgical Unit, IRCAD-IHU, University of Strasbourg, Place de l'H?pital;Department of Gastroenterology,NHC,University of Strasbourg, Place de l'H?pital;Department of Radiology,NHC, University of Strasbourg, Place de l'H?pital;Department of Pathology, NHC,University of Strasbourg,Place de l'H?pital; 出版日期：2017-01-28 出版单位：World Journal of Gastroenterology 年：2017 期：v.23 语种：英文; 页：ZXXY201704020 页数：5 CN：04 分类号：182-186

摘要

We report here the case of a young man suffering from a rare germ cell tumour. The patient was a 25-yearold man who was referred to our centre for asthenia, stinging epigastric pain, and an iron deficiency anaemia. Gastroscopy revealed a circumferential vegetating lesion on the second portion of the duodenum. The lesion was indurated at the third portion of the duodenum, responsible for a tight stenosis. A computerized tomography-scan of the chest, abdomen and pelvis, and a pancreatic MRI showed a circumferential lesion with a bi-ductal dilatation(i.e., of the common bile duct and Wirsung's duct) without metastatic localisation. The patient underwent a pancreaticoduodenectomy with lymph node dissection including all cellular adipose tissues of the hepatic pedicle from the hepatic common artery and of the retroportal lamina. Histological findings were suggestive of a duodenal embryonal carcinoma with pancreatic infiltration. This is the second published case highlighting the duodenal primitive localisation of an embryonal carcinoma with pancreatic infiltration.
        We report here the case of a young man suffering from a rare germ cell tumour. The patient was a 25-yearold man who was referred to our centre for asthenia, stinging epigastric pain, and an iron deficiency anaemia. Gastroscopy revealed a circumferential vegetating lesion on the second portion of the duodenum. The lesion was indurated at the third portion of the duodenum, responsible for a tight stenosis. A computerized tomography-scan of the chest, abdomen and pelvis, and a pancreatic MRI showed a circumferential lesion with a bi-ductal dilatation(i.e., of the common bile duct and Wirsung's duct) without metastatic localisation. The patient underwent a pancreaticoduodenectomy with lymph node dissection including all cellular adipose tissues of the hepatic pedicle from the hepatic common artery and of the retroportal lamina. Histological findings were suggestive of a duodenal embryonal carcinoma with pancreatic infiltration. This is the second published case highlighting the duodenal primitive localisation of an embryonal carcinoma with pancreatic infiltration.

引文

1 Vardaros M,Subhani M,Rizvon K,Gotlieb V,Mustacchia P,Freedman L,Garg V,Singh J,Siddiqui G.A case of gastrointestinal bleeding due to duodenal metastasis from a testicular choriocarcinoma.J Gastrointest Cancer 2013;44:234-237[PMID:22961707 DOI:10.1007/s12029-012-9433-y]
    2 Chait MM,Kurtz RC,Hajdu SI.Gastrointestinal tract metastasis in patients with germ-cell tumor of the testis.Am J Dig Dis 1978;23:925-928[PMID:568878 DOI:10.1007/BF01072468]
    3 Yokoi K,Tanaka N,Furukawa K,Ishikawa N,Seya T,Horiba K,Kanazawa Y,Yamada T,Ohaki Y,Tajiri T.Male choriocarcinoma with metastasis to the jejunum:a case report and review of the literature.J Nippon Med Sch 2008;75:116-121[PMID:18475033DOI:10.1272/jnms.75.116]
    4 K?ksal AS,Kaya?etin E,Torun S,Güne?ZE,Zengin NI.An elusive etiology of upper gastrointestinal bleeding in a young man:testis tumor.Surg Laparosc Endosc Percutan Tech 2013;23:354-356[PMID:23752011 DOI:10.1097/SLE.0b013e31828e375c]
    5 Rajpert-De Meyts E,Mc Glynn KA,Okamoto K,Jewett MA,Bokemeyer C.Testicular germ cell tumours.Lancet2016;387:1762-1774[PMID:26651223 DOI:10.1016/S0140-6736(15)00991-5]
    6 Fu S,Avezbakiyev B,Zhi W,Kodali S,Rizvon K,Alaverdian A,Freedman L,Mejia J,Shahzad G,Gotlieb V.Germ cell cancer presenting as gastrointestinal bleeding and developing brain metastases:case report and review of the literature.Future Oncol2012;8:1487-1493[PMID:23148621 DOI:10.2217/fon.12.133]
    7 Rodriguez-Lopez M,Velasco-López R,Mambrilla-Herrero S,Bailon-Cuadrado M,Plua KT,Diez-González LM,Blanco-álvarez JI,Asensio-Díaz E,Gonzalo-Martín M,Pérez-Saborido B,MarcosRodríguez JL.Duodenal involvement by seminomatous tumors.Rev Esp Enferm Dig 2015;107:640-641[PMID:26437983 DOI:10.17235/reed.2015.3646/2014]
    8 Kü?ük?ner M,Kaplan MA,?nal A,U?mak F,Firat U,I?ikdo?an A.Germ cell tumor in duodenum.Turk J Gastroenterol 2013;24:73-74[PMID:23794350 DOI:10.4318/tjg.2013.0458]
    9 Noguchi T,Takeno S,Sato T,Takahashi Y,Uchida Y,Yokoyama S.A patient with primary gastric choriocarcinoma who received a correct preoperative diagnosis and achieved prolonged survival.Gastric Cancer 2002;5:112-117[PMID:12111588 DOI:10.1007/s101200200019]