摘要
2型糖尿病(type 2 diabetes mellitus,T2DM)是一种由多因素导致的代谢性疾病,关于其发病机制的研究逐渐深入,其中肠道菌群与糖尿病的关系成为近年来研究的焦点.肠道菌群与人体健康息息相关,越来越多的研究发现肠道菌群的失调可能通过多种机制参与T2DM的发生与发展,而T2DM病患者体内代谢环境的改变又可能会影响肠道菌群的组成和功能.在这篇综述中,我们总结最近的相关研究探讨肠道菌群失调在T2DM发生和发展中的作用、有关的治疗策略以及未来的研究前景.
Type 2 diabetes mellitus(T2DM) is caused by multiple factors. The relationship between diabetes and intestinal flora has become thefocus of study in recent years. Intestinal fl ora is closely related to human health, and a growing number of studies have found that the imbalance of intestinal flora may be involved in the occurrence and development of T2DM, while metabolic environment changes in diabetics may affect the composition and function of intestinal fl ora. In this review, we will discuss the role of intestinal fl ora imbalance in the occurrence and development of T2DM, the related treatment strategies, and the future research prospects.
引文
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