基于VGG16的急性淋巴细胞白血病血液细胞显微图像人工智能辅助诊断分类研究
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  • 英文篇名:An Artificial Intelligence-Assisted Diagnostic Classification Research on Blood Cell Microscopic Image of Acute Lymphoblastic Leukemia Based on VGG16 Model
  • 作者:张海涛 ; 刘景鑫 ; 赵晓晴 ; 胡笑含 ; 李慧盈
  • 英文作者:ZHANG Haitao;LIU Jingxin;ZHAO Xiaoqing;HU Xiaohan;LI Huiying;School of Computer Science and Technology, Jilin University;Department of Radiology, China-Japan Union Hospital, Jilin University;Department of Radiology, The First Hospital, Jilin University;
  • 关键词:急性淋巴细胞白血病 ; 血液细胞显微图像 ; VGG16卷积神经网络 ; 深度学习
  • 英文关键词:acute lymphocytic leukemia;;blood cell microscopic image;;VGG16 network;;deep learning
  • 中文刊名:YLSX
  • 英文刊名:China Medical Devices
  • 机构:吉林大学计算机科学与技术学院;吉林大学中日联谊医院放射线科;吉林大学第一医院放射线科;
  • 出版日期:2019-07-10
  • 出版单位:中国医疗设备
  • 年:2019
  • 期:v.34
  • 基金:国家重点研发计划(2018YFC0116901);; 吉林大学高层次科技创新团队建设项目(2017TD-27);; 吉林省省校共建项目(SXGJXX2017-5);; 吉林省科技发展计划(20180101048JC;20190302027GX);; 吉林省教育厅“十三五”规划(JJKH20190166KJ;JJKH20180147KJ)
  • 语种:中文;
  • 页:YLSX201907001
  • 页数:5
  • CN:07
  • ISSN:11-5655/R
  • 分类号:8-11+16
摘要
针对临床医学中急性淋巴细胞白血病(Acute Lymphoblastic Leukemia,ALL)血液细胞显微图像分类易错、费时等问题,本文提出了一种基于深度学习VGG16卷积神经网络模型的方法去获取医学图像中高纬度的病理信息。该方法首先将样本数据进行预处理,清洗出符合要求的训练集和验证集,其中还用到了超像素的方法用于训练样本的目标区域提取,然后再将预处理好的数据,输入到VGG16卷积神经网络模型中,对其进行训练,最后输入验证集进入模型中进行验证,实验结果表明,该分类方法能有效地完成ALL血液细胞显微图像是否患病的分类。
        Aiming at the problem of accurate classification and time consuming in clinical medicine microscopic images of acute lymphoblastic leukemia(ALL), this paper proposed a method based on deep learning VGG16 convolutional neural network model to obtain pathological information at high latitudes in medical images. In the paper, we firstly preprocessed the sample, cleaned out the training set and verification set that met the requirements, and also used the super-pixel method to extract the target area of the training sample. Then we trained VGG16 network by inputting the preprocessed data, and finally the validation set was entered into the model for verification. The experimental result showed that the classification method could effectively complete the classification of ALL blood cell microscopic images.
引文
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