摘要
氮唑并均三嗪类化合物具有抗增殖、抗氧化、抗病毒、抗肿瘤等多种生物活性,引起了药物化学家及相关工作者的特别关注,所以关于氮唑并均三嗪类化合物的合成方法成了研究热点.从四氮唑并均三嗪、三氮唑并均三嗪、二氮唑并均三嗪这三个方面综述了这类化合物的合成方法,最后对这类化合物合成方法中存在的问题进行了讨论,并对未来的发展进行了展望.
Nitrogen zole s-triazine derivatives display several biological activities such as antiproliferative,antioxidant,antiviral,antitumor and so on.Accordingly,much effort has been made towards the development of diverse synthetic methods for nitrogen zole s-triazines.The advancements in synthesis of nitrogen zole s-triazine compounds are summarized,including tetrazolo-s-triazines,triazolo-s-triazines and diazolo-s-triazines.At last the disadvantages of these synthetic methods are discussed and prospected to the future development.
引文
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