摘要
目的分析新乡市2013至2017年HIV抗体筛查有反应样本的确证实验结果,为本市的艾滋病检测策略提供技术支持。方法对筛查实验有反应的样本进行蛋白免疫印迹试验(WB)确证,用SPSS 21.0进行统计学分析。结果 2013至2017年共确证2 428例筛查有反应标本,其中阳性1 435例,占59.1%;阴性620例,占25.5%;不确定有373例,占15.4%。各年份阳性率、阴性率、不确定率差异均有统计学意义(P<0.05)。不同来源样本的确证结果差异均有统计学意义(P<0.05),医院的阳性率最高,血站阳性率最低。在不确定样本中,单一p24条带最多。结论通过WB确证实验,可以排除初筛中的假阳性样本,对于不确定样本要增强随访。
Objective To analyze the confirmatory experimental results of HIV antibody screening positive samples in Xinxiang from 2013 to2017, and to provide technical support for the city' s AIDS laboratory testing and defense prevention policies. Methods The positive samples of HIV antibody screening from 2013 to 2017 in Xinxiang City were confirmed by western blot(WB). SPSS 21.0 was used for statistical analysis.Results A total of 2 428 samples were screened from 2013 to 2017, among which 1 435 were positive, accounting for 59.1%; 620 were negative, accounting for 25.5%; 373 were uncertain, accounting for 15.4%. The positive negative and uncertainty rate of each year were significant(P<0.05).The confirmatory results of samples from different sources were statistically significant(P<0.05), with the highest positive rate in hospitals and the lowest in blood stations. In the uncertain sample, the single p24 band was the most. Conclusion By confirming the experiment with WB, false positive samples in the primary screening can be excluded, and follow-up for uncertain samples should be enhanced.
引文
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