摘要
目的分析中西医结合治疗老年脑卒中后抑郁及改善神经功能的效果。方法选取113例老年脑卒中后抑郁患者,分为对照组56例及观察组57例,对照组应用盐酸帕罗西汀治疗,观察组应用盐酸帕罗西汀联合疏肝消郁散治疗,观察2组治疗后疗效及神经功能、抑郁情绪改善效果。结果观察组治疗后总有效率(92.98%),显著高于对照组的(78.57%,P<0.05);观察组NIHSS评分及SDS评分优于对照组(P<0.05)。结论在常规西医治疗基础上,联合应用疏肝消郁散治疗老年脑卒中后抑郁效果确切,能够有效改善患者神经功能,值得临床推广应用。
Objective To analyze the effect of integrated traditional Chinese and western medicine on depression and neurological recovery in elderly patients with stroke.Methods 113 cases of elderly stroke patients were divided into control group(56cases)and observation group(57cases),the control group was treated with Pa Rossi Dean hydrochloride,the observation group was treated with Pa Rossi Dean hydrochloride combined with Shugan Xiaoyu powder.The neurologic recovery and mental status of two groups of were analyzed.Results The total effective rate of the observation group was 92.98%,which is higher than that of the control group(P<0.05),and the NIHSS score and SDS score of the observation group were lower than those of the control group after treatment.Conclusion Shugan Xiaoyu powder combined with traditional western medicine has therapeutic effects in depression,improve neurologic function and is worthy of promotion in elderly stroke patients.
引文
[1]李录山.镇肝熄风汤加味治疗脑卒中阴虚风动型疗效观察[J].中国实用神经疾病杂志,2014,17(3):93-94.
[2]聂容荣,江伟,卢妃萍,等.加味补阳还五汤治疗缺血性脑卒中后抑郁症的临床研究[J].中成药,2016,38(4):958-960.
[3]国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994:73.
[4]国家中医药管理局脑病急症协作组.脑卒中病诊断与疗效评定标准[J].北京中医药大学学报,1996,19(1):55-56.
[5]AyerbeL,Ayis S,Wolfe CD,et al.Naturalhistory,predictors and outcomes of depression afterstroke:systematic review and meta-analysis[J].Br J Psychiatry,2013,202(3):988-990.
[6]张振香,林蓓蕾,陈颖,等.社区脑卒中患者抑郁与日常生活活动能力的相关性研究[J].中国实用神经疾病杂志,2013,16(2):12-14.
[7]李新杰,乔宇,左慧,等.益气化瘀汤联合盐酸帕罗西汀治疗老年脑卒中后抑郁疗效观察[J].世界中西医结合杂志,2016,11(9):1 271-1 273;1 281.
[8]刘崇喜.脑卒中偏瘫的中医治疗优点和辨证治疗[J].中国实用神经疾病杂志,2015,18(14):83-84.
[9]张钰,曾丽莉,刘建荣.警惕脑卒中后早期和晚期抑郁[J].中国现代神经疾病杂志,2015,15(4):263-269.
[10]秦菁菁,王海荣,赵红.卒中后情感障碍的中医诊疗新进展[J].中国中医急症,2016,25(11):2 108-2 111.
[11]安宁,解锦鼎,徐晶,等.血管认知功能障碍的行为和心理学症状研究[J].中国实用神经疾病杂志,2015,18(23):47-48.
[12]孔晔.醒脑开窍汤治疗急性脑梗死临床研究[J].中医学报,2015,30(5):722-724.
[13]林中翔.常用抗抑郁药的疗效与安全性[J].药学与临床,2014,8(4):215.
[14]王心光,樊瑞震.近十年中西医治疗脑卒中后焦虑的临床研究进展[J].光明中医,2016,31(14):2 134-2 136.
[15]龙旭东.针灸结合运动再学习技术对脑卒中患者日常生活能力及生活质量的影响[J].中国实用神经疾病杂志,2015,18(13):25-27.
[16]王庆庆,彭伟,齐向华,等.中医药治疗脑卒中后抑郁现状研究[J].光明中医,2016,31(15):2 293-2 297.
[17]王秀梅,张永艳,梁学利,等.疏肝消郁散联合西药治疗老年脑卒中后抑郁44例[J].河南中医,2016,36(8):1363-1 364.
