心钠肽对猪卵母细胞成熟、受精和大熊猫精子功能的影响

详细信息    本馆镜像全文|  推荐本文 |  |   获取CNKI官网全文

英文题名：The Effects of ANP on Porcine Oocyte Maturation, Fertilization and Giant Panda Spermatozoa Function 作者：张美佳 论文级别：博士 学科专业名称：生理学 中文关键词：心钠肽 ; 卵母细胞减数分裂 ; 精子 ; 信号转导 ; 反转录聚合酶链式反应 英文关键词：atrial natriuretic peptide ; meiosis ; spermatozoa ; signal transduction ; RT-PCR 学位年度：2005 导师：夏国良 学科代码：071003 学位授予单位：中国农业大学 论文提交日期：2005-05-01

摘要

心钠肽(atrial natriuretic peptide,ANP)主要由心脏分泌的一种小肽类激素,参与了血压调节和机体内环境的动态平衡。近年来研究发现ANP及其受体在哺乳动物卵巢和输卵管中广泛存在。一般认为促性腺激素通过cAMP信使促进卵母细胞的成熟。现在研究表明cGMP也参与卵母细胞的成熟和精子顶体反应。ANP可与受体结合,激活粒性鸟苷酸环化酶,使cGMP水平上升,从而可能在生殖系统中具有重要的生理作用。本文以猪和大熊猫为对象,研究了ANP在卵母细胞成熟和精子功能中的作用及机理。
     实验一研究了ANP对猪卵丘细胞包被的卵母细胞(cumulus-enclosed oocytes,CEOs)体外成熟和卵丘扩散的影响。当猪CEOs在添加有卵泡液的培养液中培养时,ANP剂量依赖性负调节FSH诱导的生发泡破裂(在FSH,FSH+10 nM ANP和FSH+1μM ANP处理组中的GVBD分别为:90.1:81.2和68.2%),第一极体排出(在FSH,FSH+1nM ANP和FSH+1μM ANP处理组中的PB1分别为86.1;75.3和53.3%)和卵丘扩散(在FSH,FSH+1nM ANP和FSH+1μM ANP处理组中的卵丘扩散指数分别为3.47;3.16和2.43)。该影响也表现出时间依赖性。当猪CEOs培养在无卵泡液的培养液中时,ANP显著抑制FSH诱导的GVBD(47.6%vs.83.8%)和IPB1的排出(22.4%vs.45.2%).cGMP类似物8-Br-cGMP(10μM-1 mM)可模拟ANP对GVBD、PB1和卵丘扩散的影响。ANP的作用可完全被cGMP依赖性的蛋白激酶(PKG)抑制剂KT5823所抑制,而与ANP受体C特异结合的C-ANP-(4-23)对卵母细胞体外成熟没有影响。ANP和C-ANP-(4-23)对猪卵母细胞自发成熟没有影响。这些结果表明,ANP负调节FSH诱导的猪卵母细胞减数分裂恢复、减数分裂成熟和卵丘扩散。ANP对卵母细胞成熟的影响是通过cGMP依赖性的蛋白激酶(PKG)实现的。
     实验二重点研究了ANP在猪卵母细胞成熟过程中的作用机制。结果表明ANP能抑制FSH诱导的猪卵母细胞成熟和卵丘扩散,并阻止卵母细胞和卵丘细胞中有丝分裂原蛋白激酶(mitogen-activated protein kinase,MAPK)的完全磷酸化。ANP的抑制作用可被8-Br-cGMP模拟,而蛋白激酶G(protein kinase G,PKG)抑制剂KT5823却能完全逆转。扎普司特(zaprinast)(cGMP特异的磷酸二酯酶抑制剂)能增强ANP在卵母细胞成熟中的作用。C-ANP-(4-23)(特异地与钠肽受体C(NPRC)结合的类似物)对FSH诱导的和自发的猪卵母细胞成熟没有影响。用毛喉素(forskolin,一种腺苷酸环化酶激动剂)培养猪卵母细胞得到两种不同的结果:培养44h可诱导卵丘扩散但抑制卵丘包被的卵母细胞(cumulus-enclosed oocytes,CEOs)成熟,而培养2h可诱导卵母细胞成熟。ANP和C-ANP-(4-23)都能抑制forskolin对CEOs的成熟影响,而其抑制作用百日咳毒素(pertussis toxin,PT)阻止,表明ANP和C-ANP-(4-23)对forskolin的抑制作用是通过调节卵丘细胞上的Gi蛋白实现的。所有这些结果表明ANP通过两种不同的信号机制调节FSH和forskolin在猪卵母细胞成熟中的作用:一是通过cGMP/PKG通路,另外一种是通过卵丘细胞上的NPRC受体,并激活PT敏感的Gi蛋白通路。
     实验三研究了ANP及其受体在猪精子和输卵管中的表达以及其ANP对猪精子功能的影响。RT-PCR分析表明,精子中仅存在钠肽受体A(natriuretic peptide receptors-A,NPRA)基因的表达。ANP mRNA水平在输卵管1期(OT1)、3期(OT3)和5期(OT5)中较高,在2期(OT2)中较低。NPRA mRNA水平在OT1和OT2期较低,OT3期开始上升,到OT4、OT5期达到最高。ANP能诱导猪精子发生顶体反应。当用1nM ANP处理时,其诱导顶体反应的百分率最高(34.1±2.3%)。C-ANP-(4-23)和咖啡因都对猪精子的顶体反应没有影响。ANP对精子顶体反应的影响
Atrial natriuretic peptide (ANP) or atrial natriuretic factor (ANF), a small peptide mainly produced in the heart, is involved in the regulation of blood pressure, salt and water excretion, cell proliferation and body fluid homeostasis. Recent reports show that ANP and its receptors are widely present in the ovary and oviduct. Generally, gondaotropins increase cAMP levels to induce oocyte maturation. Recent reports show that cGMP is involved in oocyte maturation. ANP exhibits the high affinity to NPRA thatcan activate particulate guanylate cyclase, which may play an important physiological role in reproductive tissues. In this study, we examined the effect and the mechanism of ANP on porcine oocyte maturation, fertilization and giant panda spermatozoa function.Experiment 1. This study examined the effect of atrial natriuretic peptide (ANP) on porcine cumulus-enclosed oocyte (CEO) maturation and cumulus expansion. ANP negatively regulated follicle-stimulating hormone (FSH)-stimulated germinal vesicle breakdown (GVBD; 90.1, 81.2 and 68.2% for FSH, FSH + 10 nM ANP and FSH +1 μM ANP, respectively), first polar body emission (PB1; 86.1, 75.3 and 53.3% for FSH, FSH + 1 nM ANP and FSH +1 μM ANP, respectively) and cumulus expansion (CEI; 3.47, 3.16 and 2.43 for FSH, FSH + 1 nM ANP and FSH +1 μM ANP, respectively) in a dose-dependently manner when CEOs were cultured in the maturation medium containing porcine follicular fluid (pFF). This negative effect showed a time-dependent manner after preincubation with 100 nM ANP for 5 h (78.4% PB1), 10 h (81.7% GVBD and 74.1% PB1), 20 h (78.5% GVBD and 68.9% PB1), and 44 h (75.3% GVBD and 60.5% PB1), respectively. ANP also significantly inhibited FSH-induced porcine oocyte GVBD (47.6% vs. 83.8%) and PB1 emission (22.4% vs. 45.2%) when CEOs were cultured in pFF-free maturation medium. cGMP analog 8-Br-cGMP (10 μM - 1 mM) mimicked the effects of ANP on GVBD, PB1 and CEI. The negative effect of ANP was completely reversed by KT5823 (a specific inhibitor of cGMP dependent protein kinase), while C-ANP-(4-23) (an analogue of ANP and specific binder for natriuretic peptide receptors-C) was ineffective in oocyte maturation. Both of ANP and C-ANP-(4-23) had no effect on spontaneous porcine oocyte maturation and cumulus expansion. These results suggest that ANP negatively regulates FSH-activated porcine oocyte meiotic resumption, meiotic maturation and cumulus expansion. The function of ANP on porcine oocyte maturation is via the cGMP dependent protein kinase (PKG) pathway.Experiment 2. The present study conducted experiments to examine the mechanism of ANP and forskolin on porcine oocyte maturation. The results revealed that ANP could inhibited follicle-stimulating hormone (FSH)-induced pig oocytes maturation and cumulus expansion and prevent the full phosphorylation of mitogen-activated protein kinase (MAPK) in both oocytes and cumulus cells, and that these inhibitory effects could be mimicked by 8-Br-cGMP, but blocked by a protein kinase G (PKG) inhibitor KT5823. Zaprinast, a cyclic guanosine 5'-monophosphate (cGMP)-specific phosphodiesterase inhibitor, could enhance the inhibitory effect of ANP on oocytes maturation. A specific analog of ANP, C-ANP-(4-23), which binds to the natriuretic peptide receptor C, had no effect in either FSH-induced or spontaneous oocytes maturation. Treatment with forskolin, a stimulator of adenylate cyclase, had a biphasic effect; 44 h treatment induced cumulus expansion but inhibited oocytes maturation while 2 h treatment induced maturation of cumulus-enclosed oocytes (CEOs). Both ANP and C-ANP-(4-23) could inhibit the effect of forskolin on CEOs maturation, and these inhibitory effects of ANP/C-ANP-(4-23) could be blocked by preincubation with pertussis toxin (PT), consistent with mediation by a Gi protein(s) in the cumulus cells. All these results suggest that ANP is a multifunctional regulator of FSH and forskolin on pig CEOs maturation by two signalling mechanisms respectively: one is via cGMP/PKG pathway; the other is via NPRC receptors in cumulus cells and

引文

Abeydeera LR, Day BN. Fertilization and subsequent development in vitro of pig oocytes inseminated in modified tris-buffered medium with frozen-thawed ejaculated spermatozoa. Biol Reprod, 1997, 57: 729-734.
    Abeydeera LR, Day BN. In vitro penetration of pig oocytes in a modified Tris-buffered medium: effect of BSA, caffeine and calcium. Theriogenology, 1997a, 48:537-744.
    Abeydeera LR, Wang WH, Prather RS, et al. Maturation in vitro of pig oocytes in protein-free culture media: fertilization and subsequent embryo development in vitro. Biol Reprod, 1998, 58:1316-1320
    Aburaya M, Minamino N, Hino J, et al. Distribution and molecular forms of brain natriuretic peptide in the central nervous system, heart and peripheral tissue of rat. Biochem Biophys Res Commun, 1989, 165:880-887.
    Acosta TJ, Berisha B, Ozawa T, et al. Evidence for a local endothelin-angiotensin-atrial natriuretic peptide system in bovine mature follicles in vitro: effects on steroid hormones and prostaglandlin secretion. Biol Reprod, 1999, 61:1419-1425.
    Akiho H, Chijiwa Y, Okabe H, et al. Interaction between atrial natriuretic peptide and vasoactive intestinal peptide in guinea pig cecal smooth muscle. Gastroenterology, 1995, 109:1105-1112.
    Adler SG, Lombardo ID, Bhanot S, et al. Cloning, characterization, and functional expression of a CNP receptor regulating CFTR in the shark rectal gland. Am J Physiol, 1999, 276: C442-C449.
    Anand-Srivastava MB, Cantin M. Atrial natriuretic factor receptors are negatively coupled to adenylate cyclase in cultured atrial and ventricular cardiocytes. Biochem Biophys Res Commun, 1986, 138:427-436.
    Anand-Srivastava MB, Franks DJ, Cantin M, et al. Atrial natriuretic factor inhibits adenylate cyclase activity. Biochem Biophys Res Commun, 1984, 121:855-862.
    Anand-Srivastava MB, Sairam MR, Cantin M. Ring-deleted analogs of atrial natriuretic factor inhibit adenylate cyclasercAMP system. J Biol Chem, 1990, 265:8566-8572.
    Anand-Srivastava MB, Sehl PD, Lowe DG. Cytoplasmic domain of natriuretic peptide receptor-C inhibits adenylyl cyclase. J Biol Chem, 1996, 271:19324-19329.
    Anand-Srivastava MB, Trachte GJ. Atrial natriuretic factor receptors and signal transduction mechanisms. Pharmacol Rev, 1993, 45:455-497.
    Anderson RA Jr, Feathergill KA, Rawlins RG, et al. Atrial natriuretic peptide: a chemoattractant of human spermatozoa by a guanylate cyclase-dependent pathway. Mol Reprod Dev, 1995, 40:371-378.
    Anderson RA, Feathergill KA, Drisdel RC, et al. Atrial natriuretic peptide (ANP) as a stimulus of the human acrosome reaction and a component of ovarian follicular fluid: correlation of follicular ANP content with in vitro fertilization outcome. J Androl, 1994, 15:61-70.
    Anderson RA, Feathergill KA, Rawlins RG, et al. Atrial natriuretic peptide: a chemoattractant of human spermatozoa by a guanylate cyclase-dependent pathway. Mol Reprod Dev, 1995, 40:371-378.
    Andrews JC, Howard JG, Bavister BD, et al. Sperm capacitation in the domestic cat (Felis bengalensis) as studied with a salt-stored zona pellucida penetration assay. Mol Reprod Dev, 1992, 31:200-207.
    Antunes-Rodrigues J, McCann SM, Rogers LC, et al. Atrial natriuretic factor inhibits dehydration- and angiotensin Ⅱ-induced water intake in the conscious, unrestrained rat. Proc Natl Acad Sci USA, 1985, 82:8720-8723.
    Antunes-Rodrigues J, McCann SM, Samson WK. Central administration of atrial natriuretic factor inhibits saline preference in the rat. Endocrinology, 1986, 118:1726-1728.
    Arnold-Reed DE, Balment RJ. Atrial natriuretic factor stimulates in-vivo and in-vitro secretion of cortisol in teleosts. J Endocrinol, 1991, 128:R17-R20.
    Austin CR. Observations on the penetration of the sperm into the mammalian egg. Aust J Sci Res B, 1951, 4:581-596.
    Bacay AC, Mantyh CR, Cohen AH, et al. Glomerular atrial natriuretic factor receptors in primary glomerulopathies: studies in human renal biopsites. Am J Kidney Dis, 1989, 14:386-395.
    Bakalska M, Mourdjeva M, Russinova A, et al. Localisation of atrial natriuretic factor (ANF) in rat testis after Leydig cell destruction: evidence for a potential role in regulating gonadal function. Endocr Regul, 1999, 33:183-191.
    Basini G, Grasselli F, Ponderato N, et al. Lipid hydroperoxide and cGMP are not involved in nitric oxide inhibition of steroidogenesis in bovine granulosa cells. Reprod Fertil Develop, 2000, 12: 289-295.
    Baxter JD, Lewicki JA, Gardner DG. Atrial natriuretic peptide. Biotechnology, 1988, 6:529-546.
    Biel M, Zong X, Distler M, et al. Another member of the cyclic nucleotide-gated channel family expressed in testis, kidney, and heart. Proceedings of the National Academy of Sciences of the USA, 1994, 91: 3505-3509.
    Biel M, Zong X, Ludwig A, et al. Molecular cloning and expression of the modulatory subunit of the cyclic nucleotide-gated cation channel. J Biol Chem, 1996, 271:6349-6355.
    Ben-Shlorno I, Kokia E, Jackson MJ, et al. Interleukin 1-β stimulates nitrite production in the rat ovary: evidence for heterologous cell-cell interaction for insulin-mediated regulation of the inducible isoform of nitric oxide synthase. Biol Reprod, 1994, 51: 310-318.
    Best PJ, Burnett JC, Wilson SH, et al. Dendroaspis natriuretic peptide relaxes isolated human arteries and veins. Cardiovasc Res, 2002, 55:375-384.
    Biesiada E, Razandi M, Levin ER. Egr-1 activates basic fibroblast growth factor transcription. Mechanistic implications for astrocyte proliferation. J Biol Chem, 1996, 271:18576-18581.
    Bornslaeger E, Wilde M, Schultz R. Regulation of mouse oocyte maturation: involvement of cyclic AMP phosphodiesterase and calmodulin. Dev Biol, 1984, 105:488-499.
    Boulanger CM, Caputo L, Levy BI. Endothelial AT-mediated release of nitric oxide decreases angiotensin Ⅱ contractions in rat carotid artery. Hypertension, 1995, 26:752-757.
    Bovy PR, O'Neal JM, Olins GM, et al. Identification of structural requirements for analogues of atrial natriuretic peptide (ANP) to discriminate between ANP receptor subtypes. J Med Chem, 1989, 32:869-874.
    Brenner BM, Ballermann BJ, Gunning ME, et al. Diverse biological actions of atrial natriuretic peptide. Physiol Rev, 1990, 70:665-699.
    Broillet MC, Firestein S. Cyclic nucleotide-gated channels, Molecular mechanisms of activation. Annals of the New York Academy of Sciences, 1999, 868:730-740.
    Brunner f, WOlkart G. Endothelial NO/cGMP System Contributes to Natriuretic Peptide-Mediated Coronary and Peripheral Vasodilation. Microv Res, 2001, 61:102-110.
    Brunswig B, Budnik LT, Mukhopadhyay Ak. Atrial natriuretic peptide-induced stimulation of cyclic GMP formation by isolated bovine luteal cells. J Reprod Fertil, 1989, 86: 659-665.
    Brunswig-Spickenheier B, Mukhopadhyay AK. Stimulation of nitric oxide-cyclic guanosine monophosphate pathway in bovine ovarian theca cells by tumor necrosis facor-a (TNFa), is this pathway implicated in the TNF alpha-induced inhibition of LH-stimulated prorenin production? Biol Reprod, 1997, 57: 700-706.
    Bryan PM, Potter LR. The atrial natriuretic peptide receptor (GC-A/NPR-A) is dephosphorylated by distinct microcystin-sensitive and magnesium-dependent protein phosphatases. J Biol Chem, 2002, 277:16041-16046.
    Buccione R, Vanderhyden BC, Caron PJ, et al. FSH-induced expansion of the mouse cumulus oophorus in vitro is dependent upon a specific factor(s) secreted by the oocyte. Dev Biol, 1990, 138:16-25.
    Budnik LT, Brunswig B, Mukhopadhyay AK. Atrial natriuretic factor stimulates luteal guanylate cyclase. Regul Pep, 1987, 19:23-34.
    Butt E, Geiger J, Jarchau T, et al. The cGMP-dependent protein kinase-gene, protein and function. Neurochem Res, 1993, 18:27-42.
    Byskov AG, Andersen CY, Nordholm L, et al. Chemical structure of sterols that activate oocyte meiosis. Nature, 1995, 374:559-562.
    Byskov AG, Yding Andersen C, Hossaini A, et al. Cumulus cells of oocyte-cumulus complexes secrete a meiosis-activating substance when stimulated with FSH. Mol Reprod Dev, 1997, 46:296-305.
    Cahill PA, Hassid A. Clearance receptor-binding atrial natriuretic peptides inhibit mitogenesis and proliferation of rat aortic smooth muscle cell. Biochem Biophys Res Commun, 1991, 179:1606-1613.
    Callahan W, Forster M, Toop T. Evidence of a guanylyl cyclase natriuretic peptide receptor in the gills of the New Zealand hagfish Eptatretus cirrhatus. J Exp Biol, 2000, 203:2519-2528.
    Cameron MR, Foster JS, Bukovsky A, et al. Activation of mitogen-activated protein kinases by gonadotropins and cyclic adenosine 5'-monophosphates in porcine granulosa cells. Biol Reprod, 1996, 55:111-119.
    Cantin M, Genest J. The heart and atrial natriuretic factor. Endocr Rev, 1985, 6:107-127.
    Carre DA, Civan MM. cGMP modulates transport across the ciliary epithelium. J Membrane Biol, 1995, 146:293-305.
    Casillas ER, Hoskins DD. Activation of monkey spermatozoa adenyl cyclase by thyroxine and triiodothyronine. Biochem Biophys Res Commun, 1970, 40:255-262.
    Chai OH, Kim EK, Lee YH, et al. Histamine release induced by dendroaspis natriuretic peptide from rat mast cells. Peptides, 2001, 22:1421-1426.
    Chander A, Fisher AB. Regulation of lung surfactant secretion, Am J Physiol, 1990, 258:L241-L253.
    Chang MC. Fertilizing capacity of spermatozoa deposited into the fallopian tubes. Nature, 1951, 168:697-698.
    Chang MS, Lowe DG, Lewis M, et al. Differential activation by atrial and brain natriuretic peptides of two different receptor guanylate cyclases. Nature, 1989, 341:68-72.
    Chao AC, de Sauvage FJ, Dong YJ, et al. Activation of intestinal CFTR Cl-channel by heat-stable enterotoxin and guanylin via cAMP-dependent protein kinase. EMBO J, 1994, 13:1065-1072.
    Chen D, Shi Q, Zhao X, et al. Studies of heterofertilization in vitro between giant panda and golden hamster. Acta Zoologica Sinica, 1989a, 35:276-280.
    Chen D, Song X, Zhou X, et al. Study on in vitro sperm capacitation and egg-penetration of giant panda. Sci China B, 1989b, 32:435-441.
    Chen D, Ye Z, Zhang Z. Ultrastructure of giant panda spermatozoa. Acta Zoologica Sinica, 1984, 30:301-304.
    Chen HH, Lainchbury JG, Burnett JC Jr. Natriuretic peptide receptors and neutral endopeptidase in mediating the renal actions of a new therapeutic synthetic natriuretic peptide dendroaspis natriuretic peptide J Am Coll Cardiol, 2002, 18:1186-1191.
    Chen ZJ, Yu L, Chang Ch. Stimulation of membrane-bound guanylate cyclase activity by 17-beta estradiol. Biochem Biophy Res Comm, 1998, 252:639-642.
    Chinkers M, Garbers DL. The protein kinase domain of the ANP receptor is required for signaling. Science, 1989, 245:1392-1394.
    Chrisman TD, Shulz S, Potter LR, et al. Seminal plasma factors that cause large elevations in cellular cyclic GMP are C-type natriuretic peptides. J Biol Chem, 1993, 268:3698-3703.
    Chu HP, Etgen AM. Ovarian hormone dependence of alpha (Ⅰ)-adrenoceptor activation of the nitric oxide-cGMP pathway: relevance for hormonal facilitation of lordosis behavior. J Neuroscience, 1999, 19:7191-7197.
    Chun SY, Eisenhauer KM, Kubo M, et al. Interleukin-1 beta suppresses apoptosis in rat ovarian follicles by increasing nitric oxide production. Endocrinology, 1995, 136:3120-3127.
    Chun SY, Eisenhauer KM, Minami S, et al. Hormonal regulation of apoptosis in early antral follicles: follicle-stimulating hormone as a major survival factor. Endocrinology, 1996, 137:1447-1456.
    Cohen D, Koh GY, Nikonova LN, et al. Molecular determinants of the clearance function of type C receptors of natriuretic peptides. J Biol Chem, 1996, 271:9863-9869.
    Collins E, Bracamonte MP, Burnett JC Jr, et al. Mechanism of relaxations to dendroaspis natriuretic peptide in canine coronary arteries. J Cardiovasc Pharmacol, 2000, 35:614-618.
    Conti M, Jin SL. The molecular biology of cyclic nucleotide phosphodiesterases. Prog Nucleic Acid Res Mol Biol, 1999, 63:1-38.
    Conti M, Kasson BG, Hsueh AJ. Hormonal regulation of 3',5'-adenosine monophosphate phosphodiesterases in cultured rat granulosa cells. Endocrinology, 1984,114:2361-2368.
    Conti M, Nemoz G, Sette C, et al. Recent progress in understanding the hormonal regulation of phosphodiesterases. End Rev, 1995, 16:370-389.
    Conti M. Phosphodiesterases and cyclic nucleotide signalling in endocrine cells. Mol Endocrinol, 2000, 14:1317-1327.
    Conti M. Specificity of the cyclic adenosine 3',5'-monophosphate signal in granulosa cell function. Biol Reprod, 2002, 67:1653-1661.
    Corompt E, Bessard G, Lantuejoul S, et al. Inhibitory effects of large Ca2q-activated Kqchannel blockers on b-adrenergic- and NO-donor-mediated relaxations of human and guinea-pig airway smooth muscles. Naunyn-Schmiedeberg's Arch Pharmacol, 1998, 357:77-86.
    Cousins KL, Farrell AP, Sweeting RM, et al. Release of atrial natriuretic factor prohormone peptides 1-30, 31-67 and 99-126 from freshwater and seawater-acclimated perfused trout (Oncorhynchus mykiss) heart. J Exp Biol, 1997, 200:1351-1362.
    Crook RB, Chang AT. Differential regulation of natriuretic peptide receptors on ciliary body epithelial cells. Biochem J, 1997, 324:49-55.
    De Bold AJ, Borenstein HB, Veress AT, et al. A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats. Life Sci, 1981, 28: 89-94.
    De Bold AJ, Kuroski-De Bold ML, Boer PH, et al. A decade of atrial natriuretic factor research. Can J Physiol Pharmacol, 1991, 69:1480-1485.
    De Bold AJ. Effects of changes in water and electrolyte balance. Proc Soc Exp Biol Med, 1979, 161:508-511.
    Dekel N, Aberdam E, Sherizly I. Sontaneous maturation in vitro of cumulus-enclosed rat oocytes is inhibited by forskolin. Biol Reprod, 1984, 31:244-250.
    Devillier P, Corompt E, Breant D, et al. Relaxation and modulation of cyclic AMP production in guinea pig tracheal smooth muscle. Eur J Pharm, 2001, 430:325-333.
    Donald JA, Vomachka AJ, Evans DH. Immunohistochemical localisation of natriuretic peptide in the brains and hearts of the spiny dogfish Squalus acanthias and the Atlantic hagfish Myxine glutinosa. Cell Tiss Res, 1992, 270:535-545.
    Donoghue AM, Howard JG, Byers AP, et al. Correlation of sperm viability with gamete interaction and fertilization in vitro in the cheetah (Acinonyx jubatus). Biol Reprod, 1992,46:1047-1055.
    Donoghue AM, Johnston LA, Seal US, et al. Ability of thawed tiger (Panthera tigris) spermatozoa to fertilize conspecific oocytes and bind and penetrate domestic cats eggs in vitro. J Reprod Fertil, 1992a, 96:555-564.
    Downs SM, Daniel SAJ, Eppig JJ. Induction of maturation in cumulus cell-enclosed mouse oocytes by follicle-stimulating hormone and epidermal growth factor: evidence for a positive stimulus of somatic cell origin. J Exp Zool, 1988, 245:86-96.
    Downs SM. Specificity of epidermal growth factor action on maturation of the murine oocyte and cumulus oophorus in vitro. Biol Reprod, 1989, 41:371-379.
    Draijer R, Atsma DE, van der Laarse A, et al. cGMP and nitric oxide modulate thrombin-induced endothelial permeability, regulation via different pathways in human aortic and umbilical vein endothelial cells. Circul Res, 1995, 76:199-208.
    Drewett JG, Fendly BM, Garbers DL, et al. Natriuretic peptide receptor-B (guanylyl cyclase-B) mediates Ctype natriuretic peptide relaxation of precontracted rat aorta. J Biol Chem, 1995, 270:4668-4674.
    Drewett JG, Ziegler RJ, Trachte GJ. Neuromodulatory effects of atrial natriuretic peptides correlate with an inhibition of adenylate cyclase but not an activation of guanylate cyclase. J Pharmacol Exp Ther, 1992, 260:689-696.
    Drisdel RC, Mack SR, Anderson RA, et al. Purification and partial characterization of acrosome reaction inhibiting glycoprotein from human seminal plasma. Biol Reprod, 1995, 53:201-208.
    Duda T, Sharma RK. Regulation of guanylate cyclase activity by atrial natriuretic factor and protein kinase C. Mol Cell Biochem, 1990, 93:179-184.
    Duff DW, Olson KR. Trout vascular and renal responses to atrial natriuretic factor and heart extracts. Am J Physiol, 1986, 251:R639-R642.
    Duhe RJ, Nielsen MD, Dittman AH, et al. Oxidation of critical cysteine residues of type Ⅰ adenylyl cyclase by o-iodosobenzoate or nitric oxide reversibly inhibits stimulation by calcium and calmodulin. J Biol Chem, 1994, 269:7290-7296.
    Elfman C, Corbett JA, Misko TP, et al. Nitric oxide mediates interleukin 1β induced cellular cytotoxicity in the rat ovary: a potential role for nitric oxide in the ovulatory process. J Clin Invest, 1993, 92:3053-3056.
    Ellis JL. Role of soluble guanylyl cyclase in the relaxations to a nitric oxide donor and to nonadrenergic nerve stimulation in guinea pig trachea and human bronchus. J Pharmacol Exp Ther, 1997, 280:1215-1218.
    Elvin JA, Yan C, Matzuk MM. Oocyte-expressed TGF-beta superfamily members in female fertility. Mol Cellul End, 2000, 159:1-5.
    Eppig JJ. Gonadotropin stimulation of the expansion of cumulus oophori isolated from mice: general conditions for expansion in vitro. J Exp Zool, 1979, 208:111-120.
    Eppig JJ. Oocyte control of ovarian follicular development and function in mammals. Reproduction, 2001, 122:1275-1282.
    Eppig JJ. Regulation of mammalian oocyte maturation. In: EY Adashi and PCK Leung (Ed.), The ovary. New York Raven Press, 1993, p.185-208.
    Erickson GF, Hsueh AJW. Stimulation of aromatase activity by follicle-stimulating hormone in rat granulose cells in vivo and in vitro, Endocrinology, 1978, 102:1275-1282.
    Evans DH, Toop T, Donald J, et al. C-type natriuretic peptides are potent dilators of shark vascular smooth muscle. J Exp Zool, 1993, 265:84-87.
    Evans DH. An emerging role for a cardiac peptide hormone in fish osmoregulation. Annu Rev Physiol, 1990,52:43-60.
    Evrard A, Hober C, Racadot A, et al. Atrial natriuretic hormone and endocrine functions. Ann Biol Clin (paris), 1999, 57:149-155.
    Fabrega E, Crespo J, Rivero M, et al. Dendroaspis natriuretic peptide in hepatic cirrhosis. Am J Gastroenterol, 2001, 96:2724-2729.
    Fagbohun CF, Downs SM. Maturation of the mouse oocyte-cumulus cell complex: stimulation by lectins. Biol Reprod, 1990, 42:413-423.
    Fan HY, Tong C, Lian L, et al. Characterization of ribosomal S6 protein kinase p90rsk during meiotic maturation and fertilization in pig oocytes: mitogen-activated protein kinase-associated activation and localization. Biol Reprod, 2003, 68:968-977.
    Farrell AP, Olson KR. Cardiac natriuretic peptides: A physiological lineage of cardioprotective hormone? Physiol Biochem Zool, 2000, 73:1-11.
    Fernandes LB, Preuss JMH, Goldie RG. Epithelial modulation of the relaxant activity of atriopeptides in rat and guinea-pig tracheal smooth muscles. Eur J Pharmacol, 1992, 212:187-194.
    Fernandez-Durango R, Moya FJ, Ripodas A, et al. Type B and type C natriuretic peptide receptors modulate intraocular pressure in the rabbit eye. Eur J Pharmacol, 1999,364:107-113.
    Fernandez-Durango R, Nunez DJR, Brown MJ. Messenger RNAs encoding the natriuretic peptides and their receptors are expressed in the eye. Exp Eye Res, 1995, 53:591-596.
    Fisher DL, Brassac T, Galas S, et al. Dissociation of MAP kinase activation and MPF activation in hormone-stimulated maturation of Xenopus oocytes. Development, 1999,126:4537-4546.
    Flynn TG, De Bold ML, De Bold AJ. The amino acid sequence of an atrial peptide with potent diuretic and natriuretic properties. Biochem Biophys Res Commun, 1983, 117:859-865.
    Forte LR, Thorne PK, Eber SL, et al. Stimulation of intestinal Cl-transport by heat-stable enterotoxin: activation of cAMP-dependent protein kinase by cGMP. American J Physiol, 1992, 263:C607-C615.
    Fowkes RC, McArdle CA. C-type natriuretic peptide: an important neuroendocrine regulator? Trends Endocrinol Metab, 2000,11:333-338.
    Fraser LR. Accelerated mouse sperm penetration in vitro in the presence of caffeine. J Reprod Fertil, 1979, 57:377-384.
    Fujii K, Ishimatsu T, Kuriyama H. Mechanism of vasodilation induced by alpha-human atrial natriuretic polypeptide in rabbit and guinea-pig renal arteries. J Physiol (Lond), 1986, 377:315-332.
    Fukuzawa A, Watanabe TX, Itahara Y, et al. B-type natriuretic peptide isolated from frog cardiac ventricles. Biochem Biophys Res Commun, 1996, 222:323-329.
    Fuller F, Porter JG, Arfsten AE, et al. Atrial natriuretic peptide clearance receptor. Complete sequence and functional expression of cDNA clones. J Biol Chem, 1988, 263:9395-9401.
    Funahashi H, Cantley TC, Day BN. Different hormonal requirement of pig oocyte-cumulus complexes during maturation in vitro. J Reprod Fertil, 1994, 101:159-165.
    Furchgott RF, Jothianandan D. Endothelium-dependent and independent vasodilation involving cyclic GMP: relaxation induced by nitric oxide, carbon monoxide and light. Blood Vessels, 1991, 28:52-62.
    Gao Y, Tolsa JF, Shen H, et al. Effect of selective phosphodiesterase inhibitors on response of ovine pulmonary arteries to prostaglandin oestradiol. J Applied Physiol, 1998, 84:13-18.
    Garbers DL, First NL, Gorman SK, et al. The effects of cyclic nucleotide phosphodiesterase inhibitors on ejaculated porcine spermatozoa metabolism. Biol Reprod, 1973, 8:599-606.
    Garbers DL, First NL, Sullivan JJ, et al. Stimulation and maintenance of ejaculated bovine spermatozoa respiration and motility by caffeine. Biol Reprod, 1971, 5:336-339.
    Gardner DG, Vlasuk GP, Baxter JD, et al. Identification of atrial natriuretic factor gene transcripts in the central nervous system of the rat. Proc Natl Acad Sci USA, 1987, 84:2175-2179.
    Garthwaite J, Southam E, Boulton CL, et al. Potent and selective inhibition of nitric oxide-sensiw tive guanylyl cyclase by 1H-1,2,4 oxadiazolo 4,3-a quinoxalin-1-one. Mol Pharmacol, 1995, 48:184-188.
    Gauer OH, Henry JP, Behn C. The regulation of extracellular fluid volume. Annu Rev Physiol, 1970, 32:572-594.
    Gegenhuber A, Mueller T, Firlinger F, et al. Time course of B-type natriuretic peptide (BNP) and N-terminal proBNP changes in patients with decompensated heart failure. J Clin Chem, 2004, 50:454-456.
    Gerbes AL, Dagnino L, Nguyen T, et al. Transcription of brain natriuretic peptide and atrial natriuretic peptide genes in human tissues. J Clin Endocrinol Metab, 1994, 78:1307-1311.
    Gonzalez-Robayna IJ, Falender AE, Ochsner S, et al. Follicle-Stimulating hormone (FSH) stimulates phosphorylation and activation of protein kinase B (PKB/Akt) and serum and glucocorticoid-induced kinase (Sgk): evidence for A kinase-independent signaling by FSH in granulosa cells. Mol End, 2000, 14:1283-1300.
    Grasselli F, Ponderato N, Basini G, et al. Nitric oxide synthase expression and nitric oxide/cyclic GMP pathway in swine granulose cells. Domes Anim End, 2000, 20:241-252.
    Gudi T, Casteel DE, Vinson C, et al. NO activation of fos promoter elements requires nuclear translocation of G-kinase I and CREB phosphorylation but is independent of MAP kinase activation. Oncogene, 2000, 19:6324-6333.
    Gutkowska J, Cantin M, Genest J, et al. Release of immunoreactive atrial natriuretic factor from the isolated perfused rat lung. FEBS Lett, 1987, 214:17-20.
    Gutkowska J, Jankowski M, Sairam MR, et al. Hormonal regulation of natriuretic peptide system during induced ovarian follicular development in the rat. Biol Reprod, 1999, 61:162-170.
    Gutkowska J, Nemer M. Structure, expression, and function of atrial natriuretic factor in extraatrial tissues. Endocr Rev, 1989, 10:519-536.
    Gutkowska J, Tremblay J, Antakly T, et al. The atrial natriuretic peptide system in rat ovaries. Endocrinology, 1993, 132:693-700.
    Ha KC, Chae HJ, Piao CS, et al. Dendroaspis natriuretic peptide induces the apoptosis of cardiac muscle cells. Immunopharmacol Immunotoxicol, 2005, 27:33-51.
    Hagiwara H, Inoue A, Yamaguchi A, et al. cGMP produced in response to ANP and CNP regulates proliferation and differentiation of osteoblastic cells. Am J Physiol, 1996, 270:C1311-C1318.
    Hamet P, Tremblay J. Evaluating atrial natriuretic peptide-induced cGMP production by particulate guanylyl cyclase stimulation in vitro and in vivo. Methods Enzymol, 1991, 195:447-461.
    Hanafy KA, Krumenacker JS, Murad F. NO, nitrotyrosine, and cyclic GMP in signal transduction. Med Sci Mon, 2001, 7:801-819.
    Handrow RR, Lenz RW, Ax RL. Structural comparisons among glycosaminoglycans to promote an acrosome reaction in bovine spermatozoa. Biochem Biophys Res Commun, 1982, 107:1326-1332.
    Hanke CJ, Drewett JG, Myers CR, et al. Nitric oxide inhibits aldosterone synthesis by a guanylyl cyclase-independent effect. Endocrinology, 1998, 139:4053-4060.
    Hans K, Mery B, Hans K, et al. B-type natriuretic peptide (BNP) and N-terminal proBNP in patients with end-stage heart failture supported by a left ventricular assist device. J Clin Chem, 2004, 50:1670-1672.
    Harlow BL, Signorello LB. Factors associated with early menopause. Maturitas, 2000, 35:3-9.
    Hempelmann RG, Seebeck J, Ziegler A, et al. Effects of potassium channel inhibitors on the relaxation induced by the nitric oxide donor diethylamine nitric oxide in isolated human cerebral arteries. J Neurosurg, 2000, 93:1048-1054.
    Hernandez F, Alexander SPH, Kendall DA. Natriuretic peptide-induced cyclic GMP accumulation in adult guinea-pig cerebellar slices. Br J Pharmacol, 1994, 113:216-220.
    Hickey GJ, Chen S, Besman MJ, et al. Hormonal regulation, tissue distribution and content of aromatase cytochrome P450 messenger ribonucleic acid and enzyme in rat ovarian follicles and corpora lutea: relationship to estradiol synthesis. Endocrinology, 1988, 122:1426-1436.
    Homa ST. Effects of cyclic AMP on the spontaneous meiotic maturtion of cumulus-free bovine oocytes cultured in chemically defined medium. J Exp Zool, 1988, 248:222-231.
    Howard JG, Bush M, Wildt DE. Teratospermia in domestic cats compromises penetration of zona-free hamster ova and cat zonae pellucidae. J Androl, 1991, 12:36-45.
    Howard JG. Assisted reproductive techniques in nondomestic carnivores. In: M Fowler and R Miller (Ed.), Zoo and Wild Animal Medicine: Current Therapy Ⅳ, Philadelphia: WB Saunders Co, 1999, p.449-457.
    Hsueh AJ, Adashi EY, Jones PB, et al. Hormonal regulation of the differentiation of cultured ovarian granulose cells. End Rev, 1984, 5:76-127.
    Hu J. Studies on reproductive biology of the giant panda. In: S Asakura and S Nakagawa (Ed.), Proceedings of the Second International Symposium on Giant Panda. Tokyo Zoological Park Society, 1990, p.73-76.
    Hubbard CJ, Greenwald GS. Cyclic nucleotides, DNA, and steroid levels in ovarian follicles and corpora lutea of the cyclic hamster. Biol Reprod, 1982, 26:230-240.
    Hubbard CJ, Price J. The effects of follicle-stimulating hormone and cyclic guanosine 3',5'-monophosphate on cyclic adenosine 3',5'-monophosphate-phosphodiesterase and resumption of meiosis in hamster cumulus-oocyte complexes. Biol Reprod, 1988, 39:829-838.
    Hubbard CJ. Ovarian cAMP and cGMP fluctuations in the hamster during the oestrous cycle. J Reprod Fertil, 1980, 59:351-355.
    Hunt PJ, Richards AM, Espiner EA, et al. Bioactivity and metabolism of C-type natriuretic peptide in normal man. J Clin End Meta, 1994, 78:1428-1435.
    Hunter RHF, Polge C. Maturation of follicular oocytes in the pig after injection of human chorionic gonadotropin. J Reprod Fertil, 1966, 12:525-531.
    Hunter RHF. Sperm:egg ratios and putative molecular signals to modulate gamete interactions in polytocous mammals. Mol Reprod Dev, 1993, 35:324-327.
    Hwang TL, Wu CC, Teng CM. Comparison of two soluble guanylyl cyclase inhibitors, methylene blue and ODQ, on sodium nitroprusside-induced relaxation in guinea-pig trachea. Br J Pharmacol, 1998, 125:1158-1163.
    Ijioma SC, Challiss RAJ, Boyle JP. Comparative effects of activation of soluble and particulate guanylyl cyclase on cyclic GMP elevation and relaxation of bovine tracheal smooth muscle. Br J Pharmacol, 1995, 115:723-732.
    Imura R, Sano T, Goto J, et al. Inhibition by HS-142-1, a novel nonpeptide atrial natriuretic peptide antagonist of microbial origin, of atrial natriuretic peptideinduced relaxation of isolated rabbit aorta through the blockade of guanylyl cyclase-linked receptors. Mol Pharmacol, 1992, 42: 982-990.
    Inoue M, Naito K, Nakayama T, et al. Mitogen-activated protein kinase translocates into the germinal vesicle and induces germinal vesicle breakdown in porcine oocytes. Biol Reprod, 1998, 58:130-136.
    Ishii Y, Watanabe T, Watanabe M, et al. Effects of atrial natriuretic peptide on type Ⅱ alveolar epithelial cells of the rat lung. Autoradiographic and morphometric studies. J Anat, 1989, 166:85-95.
    Ishimaru RS, leung K, Hong L, et al. Inhibitory effects of nitric oxide on estrogen production and cAMP levels in rat granulosa cell cultures. J End, 2001, 168:249-255.
    Itoh H, Nakao K, Sugawara A, et al. Gamma-atrial natriuretic polypeptide (gamma-ANP)-derived peptide in human plasma: cosecretion of N-terminal gamma-ANP fragment and alpha-ANP. J Clin Endocrinol Metab, 1988, 67:429-437.
    Itoh H, Nakao K. Antagonism between the vascular renin-angiotensin and natriuretic peptide systems in vascular remodeling. Blood Pressure (suppl.), 1994, 49-53.
    Ivanova MD, Gregoraszczuk EL, Augustowska K, et al. Localization of atrial natriuretic peptide in pig granulosa cells isolated from ovarian follicles of various size. Reprod Biol, 2003, 3:173-181.
    Jablonka-Shariff A, Olson LM. Hormonal regulation of nitric oxide synthases and their cell-specific expression during follicular development in the rat ovary. Endocrinology, 1997, 138:460-468.
    Jaiswal RK, Jaiswal N, Sharma RK. Negative regulation of atrial natriuretic factor receptor coupled membrane guanylate cyclase by phorbol ester. Potential protein kinase C regulation of cyclic GMP signal in isolated adrenocortical carcinoma cells of rat. FEBS Lett, 1988, 227:47-50.
    Jankowski M, Reis AM, Mukaddam-Daher S, et al. C-type natriuretic peptide and the guanylyl cyclase receptors in the rat ovary are modulated by the estrous cycle. Biol Reprod, 1997, 56:59-66.
    Jin H, Chen YF, Yang RH, et al. Impaired release of atrial natriuretic factor in NaCl-loaded spontaneously hypertensive rats. Hypertension, 1994, 11:739-744.
    John SW, Krege JH, Oliver PM, et al. Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension. Science, 1995, 267:679-681.
    Johnson KM, Hughes FM Jr, Fong YY, et al. Effects of atrial natriuretic peptide on rat ovarian granulose cell steroidogenesis in vitro. Am J Reprod Imm, 1994, 31:163-168.
    Johnson MC, Diaz HA, Stocco C, et al. Antisteroidogenic action of nitric oxide on human corpus luteum in vitro: mechanism of action. Endocrine, 1999, 11:31-36.
    Jones TR, Charrette L, Garcia ML, et al. Interaction of iberiotoxin with b-adrenoceptor agonists and sodium nitroprusside on guinea pig trachea. J Appl Physiol, 1993, 74:1879-1885.
    Jones TR, Charrette L, Garcia ML, et al. Selective inhibition of relaxation of guinea-pig trachea by charybdotoxin, a potent Ca2q-activated Kq channel inhibitor. J Pharmacol Exp Ther, 1990, 255:697-706.
    Joyce C, Nuzzo N, Wilson L, Zaneveld LJD. Evidence for a role of cyclooxygenase (prostaglandin synthetase) and prostaglandins in the sperm acrosome reaction and fertilization. J Androl, 1987, 8:74-82.
    Kadowaki K, Hirota K, Koike K, et al. Atrial and brain natriuretic peptides enhance dopamine accumulation in cultured rat hypothalamic cells including dopaminergic neurons. Neuroendocrinology, 1992, 56:11-17.
    Kagabu S, Kodama H, Fukuda J, et al. Inhibitory effects of nitric oxide on the expression and activity of aromatase in human granulosa cells. Mol Hum Reprod, 1999, 5:396-401.
    Kaiya H, Takei Y. Changes in plasma atrial and ventricular natriuretic peptide concentrations after transfer of eels from fresh water to seawater or vice versa. Gen Comp Endocrinol, 1996, 104:337-345.
    Kanda F, Sarnacki P, Arieff AI. Atrial natriuretic peptide inhibits amiloride-sensitive sodium uptake in rat brain. Am J Physiol, 1992, 263:R279-R283.
    Kangawa K, Fukuda A, Kubota I, et al. Human atrial natriuretic polypeptides (hANP): purification, structure synthesis and biological activity. J Hypertens Suppl, 1984, 2:S321-S323.
    Kangawa K, Matsuo H. Purification and complete amino acid sequence of alpha-human atrial natriuretic peptide alpha-hANP. Biochem Biophys Res Commun, 1983, 118:131-139.
    Kapoun AM, Faquan L, O'Young G, et al. Functional opposition to transforming growth factor-βin primary human cardiac fibroblasts: fibrosis, myofibroblast conversion, proliferation, and inflammation. J Circ Res, 2004, 94:453-461.
    Karczewski P, Kuschel M, Baltas LG, et al. Site-specific phosphorylation of a phospholamban peptide by cyclic nucleotide- and Ca2+/calmodulin-dependent protein kinases of cardiac sarcoplasmic reticulum. Basic Res card, 1997, 92:37-43.
    Karnaky Jr K, Valentich JD, Currie MG, et al. Atriopeptin stimulates chloride secretion in cultured shark rectal gland cells. Am J Physiol, 1991, 260:C1125-C1130.
    Kashiwagi M, Katafuchi T, Kato A, et al. Cloning and properties of a novel natriuretic peptide receptor, NPR-D. Eur J Biochem, 1995, 233:102-109.
    Katafuchi T, Takashima A, Kashiwagi M, et al. Cloning and expression of eel natriuretic peptide receptor B (NPR-B) and its comparison with the mammalian counterparts. Eur J Biochem 1994, 222:835-842.
    Kawaguchi H, Sawa H, Yasuda H. Effect of atrial natriuretic factor on angiotensin converting enzyme. J Hypertension, 1990, 8:749-753.
    Kenny AJ, Bourne A, Ingram J. Hydrolysis of human and pig brain natriuretic peptides, urodilatin, C-type natriuretic peptide and some C-receptor ligands by endopeptidase-24.11. Bioche J, 1993, 291:83-88.
    Kenny AJ, Stephenson SL. Role of endopeptidase-24.11 in the inactivation of atrial natriuretic peptide. FEBS Lett, 1988, 232:1-8.
    Khurana ML, Pandey KN. Atrial natriuretic peptide inhibits the phosphoinositide hydrolysis in murine Leydig tumor cells. Mol Cell Biochem, 1996, 158:97-105.
    Khurana VG, Wijdicks EF, Heublein DM, et al. A pilot study of dendroaspis natriuretic peptide in aneurysmal subarachnoid hemorrhage. Neurosurgery, 2004, 55:69-75.
    Kiemer AK, Vollmar AM, Bilzer M, et al. Atrial natriuretic peptide reduces expression of TNF-a mRNA during reperfwion of the rat liver upon decreased activation of NF-_kB and AP-1. J Hepat, 2000, 33:236-246.
    Kiemer AK, Vollmar AM. Autocrine regulation of the inducible nitric oxide synthase by Atrial Natriuretic Peptide in macrophages. J Biol Chem, 1998, 273:13444-13451.
    Kiemer AK, Vollmar AM. Elevation of intracellular calcium levels contributes to the inhibition of nitric oxide production by atrial natriuretic peptide. Immunol Cell Biol, 2001, 79:11-17.
    Kikuchi K, Onishi A, Kashiwazaki N, et al. Successful piglet production after transfer of blastocysts produced by a modified in vitro system. Biol Reprod, 2002, 66:1033-1041.
    Kim JH, Yang SH, Yu MY, et al. Dendroaspis natriuretic peptide system and its paracrine function in rat colon. Regul Pept, 2004, 120:93-98.
    Kim SH, Cho KW, Hwang YH, et al. Ovarian atrial natriuretic peptide during the rat estrous cycle. Life Sci, 1992a, 51:1291-1299.
    Kim SH, Cho KW, Kim SZ, et al. Characterization of the atrial natriuretic peptide system in the oviduct. Endocrinology, 1997, 138:2410-2416.
    Kim SH, Cho KW, Lim SH, et al. Presence and release of immunoreactive atrial natriuretic peptide in granulosa cells of the pig ovarian follicle. Regul Pept, 1992b, 42:153-162.
    Kim SH, Cho KW, Oh SH, et al. Immunoreactive atrial natriuretic peptides in the oocyte. Comp Biochem Physiol Com Physiol, 1993,104:219-223.
    Kim SH, Cho KW, Seul KH, et al. Presence of immunoreactive atrial natriuretic peptide in follicular fluid, ovary and ovarian perfusates. Life Sci, 1989, 45:1581-1589.
    Kim SH, Han JH, Lim SH, et al. Attenuation of inhibitory effect of CNP on the secretion of ANP from hypertrophied atria. Am J Physiol, 2001, 28l:R1456 - R1463.
    Kim SJ, Shinjo M, Usuki S, et al. Binding sites for atrial natriuretic peptide in high concentration in human ovaries. Biomed Res, 1987, 8:415-420.
    Kim SW, Lee JU, Kim SZ, et al. Enhanced Dendroaspis natriuretic peptide immunoreactivity in experimental ureteral obstruction.Nephron, 2002, 92:369-372.
    Kim SZ, Kang SY, Lee SJ, et al. Localization of receptors for natriuretic peptide and endothelin in the duct of the epididymis of the freshwater turtle. Gen Comp Endocrinol, 2000,118:26-38.
    King GJ, Macpherson JW. A comparison of two methods for boar semen collection. J Anim Sci, 1973, 36:563-565.
    Kitano K, Fukuda Y, Nagahira K, et al. Production and characterization of monoclonal antibodies against human natriuretic peptide receptor-A or -B. Immunol Lett, 1995, 47:215-222.
    Knecht M, Catt KJ. Induction of LH receptors by adenosine-3',5'-monophosphate in cultured granulose cells. Endocrinology, 1982,111:1192-1200.
    Knorr A, Kazda S, Neuser D, et al. Long-term protective effects of nitrendipine in experimental hypertension. J Cardiovasc Pharmacol, 1991,18:S1-S4.
    Kobayashi O, Miwa H, Watanabe S, et al. Cyclooxygenase-2 downregulates inducible nitric oxide synthase in rat intestinal epithelial cells. Am J Physiol, 2001, 281:G688-G696.
    Koh GY, Nussenzweig DR, Okolicany J, et al. Dynamics of atrial natriuretic factor-guanylate cyclase receptors and receptor-ligand complexes in cultured glomerular mesangial and renomedullary interstitial cells. J Biol Chem, 1992, 267:11987-11994.
    Kojima M, Minamino N, Kangawa K, et al. Cloning and sequence analysis of a cDNA encoding a precursor for rat C-type natriuretic peptide (CNP). FEBS lett, 1990, 276:209-213.
    Kokkonen K, Vierimma H, Bergstrom S, et al. Novel salmon cardiac peptide hormone is released from the ventricle by regulated secretory pathway. Am J Physiol, 2000, 278:E285-E292.
    Koller KJ, de Sauvage FJ, Lowe DG, et al. Conservation of the kinaselike regulatory domain is essential for activation of the natriuretic peptide receptor guanylyl cyclases. Mol Cell Biol, 1992, 12:2581-2590.
    Komalavilas P, Lincoln TM. Phosphorylation of the inositol 1,4,5-trisphosphate receptor, Cyclic GMP-dependent protein kinase mediates cAMP and cGMP dependent phosphorylation in the intact rat aorta. J Biol Chemist, 1996, 271:21933-21938.
    Komatsu Y, Nakao K, Suga S, et al. C-type natriuretic peptide (CNP) in rats and humans. Endocrinology, 1991, 129:1145-1149.
    Konrad EM, Thibault G, Schiffrin EL, et al. Atrial natriuretic factor receptor subtypes in the rat central nervous system. Hypertension, 1991,17:1144-1151.
    Kubo M, Nakaya Y, Matsuoka S, et al. Atrial natriuretic factor and isosorbide dinitrate modulate the gating of ATP-sensitive Kq-channels in cultured vascular smooth muscle cells. Circ Res, 1994, 74:471-476.
    Kumar R, von Geldern TW, Calle RA, et al. Stimulation of atrial natriuretic peptide receptorrguanylyl cyclase-A signaling pathway antagonizes the activation of protein kinase C-a in murine Leydig cells. Biochimica et Biophysica Acta, 1997, 1356:221-228
    Kurtz A, Gotz KH, Hamann M, et al. Stimulation of rennin secretion by nitric oxide is mediated by phosphodiesterase 3. Proceedings of the National Academy of Sciences of the USA, 1998, 95:4743-4747.
    LaPolt PS, Hong L-Sh. Inhibitory effects of superoxide dismutase and cyclic guanosine 3',5'-monophosphate on estrogen production in cultured rat granulosa cells. Endocrinology, 1995, 136:5536-5539.
    LaPolt PS, Leung K, Ishimaru R, et al. Roles of cyclic GMP in modulating ovarian functions. Reprod Biomed, 2003, 6:15-23.
    Ledda S, Bogliolo L, Leoni G, et al. Influence of vasoactive intestinal peptide (VIP), atrial natriuretic peptide (ANP) and insulin-like growth factor-I (IGF-I) on in vitro maturation of prepubertal and adult sheep oocytes. Zygote, 1996, 4:343-348.
    Ledsome JR, Wilson N, Coumeya CA, et al. Release of atrial natriuretic peptide by atrial distension. Can J Physiol Pharmacol, 1985, 63:739-742.
    Lee J, Kim SW. Dendroaspis natriuretic peptide administered intracerebroventricularly increases renal water excretion. Clin Exp Pharmacol Physiol, 2002, 29:195-197.
    Lee J, Lee SH, Kang DG, et al. Effects of nitric oxide synthesis inhibition on the atrial natriuretic peptide system. Pharmacological Research, 2000, 42:275-279.
    Lee J, Malvin RL. Natriuretic response to homologous heart extract in aglomerular toadfish. Am J Physiol, 1987, 252:R1055-R1058.
    Lee MA, West RE, Moss J. Atrial natriuretic factor reduces cyclic adenosine monophosphate content of human fibroblasts by enhancing phosphodiesterase activity. J Clin Invest, 1988, 82:388-393.
    Lee S, Park SK, Kang KP, et al. Relationship of plasma Dendroaspis natriuretic peptide-like immunoreactivity and echocardiographic parameters in chronic haemodialysis patients. Nephrology (Carlton), 2004, 9:171-175.
    Lenz RW, Ball GD, Lohse JK, et al. Chondroitin sulfate facilitates an acrosome reaction in bovine spermatozoa as evidenced by light microscopy, electron microscopy and in vitro fertilization. Biol Reprod, 1983, 28:683-690.
    Leskinen H, Vuolteenaho O, Leppaluoto J, et al. Role of nitric oxide on cardiac hormone secretion: effect of NG-nitro-L-arginine methyl ester on atrial natriuretic peptide and brain natriuretic peptide release. Endocrinology, 1995, 136:1241-1249.
    Levin ER, Natriuretic peptide C-receptor: more than a clearance receptor. Am J Physiol, 1992, 264:E483-E489.
    Levin ER. Natriuretic peptide C-receptor: more than a clearance receptor. Am J Physiol, 1993, 264:E483-E489.
    Lew RA, Baertschi AJ. Endothelial cells stimulate ANF secretion from atrial myocytes in coculture. Biochem Biophys Res Commun, 1989, 163:701-709.
    Lewinski A, Szkudlinski M, Szymczykiewicz P, et al. Factors regulating growth processes in the ovary. Postepy Hig Med Dosw, 1992, 46:173-189.
    Lisy O, Jougasaki M, Heublein DM, et al. Renal actions of synthetic dendroaspis natriuretic peptide. Kidney Int, 1999, 56:502-508.
    Lisy O, Lainchbury JG, Leskinen H, et al. Therapeutic actions of a new synthetic vasoactive and natriuretic peptide, dendroaspis natriuretic peptide, in experimental severe congestive heart failure. Hypertension, 2001, 37:1089-1094.
    Liu D, Fang J, Sun R, et al. Behavioural comparison in individuals of different sexual ability in giant panda (Ailuropoda melanoleuca). Acta Zoologica Sinica, 1998, 44:27-34.
    Liu W. Litter size and survival rate in captive giant pandas (Ailuropoda melanoleuca). Int Zoo Yb, 1988, 27:304-307.
    Loretz CA, Pollina C. Natriuretic peptides in fish physiology. Comp Biochem Physiol, 2000, 125:169-187.
    Loretz CA, Takei Y. Natriuretic peptide inhibition of intestinal salt absorption in the Japanese eel: physiological significance. Fish Physiol Biochem, 1997, 17:319-324.
    Lu YF, Kandel ER, Hawkins RD. Nitric oxide signaling contributes to late-phase LTP and CREB phosphorylation in the hippocampus. J Neurosci, 1999, 19:10250-10261.
    Lu ZX, Xia GL, Zhang JC. Protein kinase C, rather than protein kinase A is involved in follicle-stimulating hormone-mediated meiotic resumption of mouse cumulus cell-enclosed oocytes in hypoxanthine-supplemented medium. Mol Cell Endocrinol, 2001, 182:225-232.
    Lynham JA, Harrison RA. Use of stored pig eggs to assess boar sperm fertilizing functions in vitro. Biol Reprod, 1998, 58:539-550.
    Maack T, Suzuki M, Almeida FA, et al. Physiological role of silent receptors of atrial natriuretic factor. Science, 1987, 238:675-678.
    Maack T. Role of atrial natriuretic factor in volume control. Kidney Int, 1996, 49:1732-1737.
    Maack T. Receptors of atrial natriuretic factor. Ann Rev Physiol, 1992, 54:11-27.
    MacFarland RT, Zelus BD, Beavo JA. High concentrations of a cGMP-stimulated phosphodiesterase mediate ANP-induced decreases in cAMP and steroidogenesis in adrenal glomerulosa cells. J Biol Chem, 1991, 266:136-142.
    Makris A, Ryan KJ. Cyclic AMP and cyclic GMP accumulation by isolated hamster granulosa cells stimulated by LH and FSH. Acta Endocrinologica (Copenhagen), 1978, 89:173-181.
    Mandich A, Isola G, Massari A. Atrial natriuretic peptide in trout ovarian follicles. Gen Comp Endocrinol, 1991, 84:419-425.
    Masuda M, Kubota T, karnada S, et al. Nitric oxide inhibits steroidogensis in cultured porcine granulosa cells. Mol Hum Reprod, 1997, 3:285-292.
    Matsumi H, Yano T, Koji T, et al. Expression and localization of inducible nitric oxide in the follicular development. Biochem Biophy Res Comm, 1998, 243:67-72.
    McCauley TC, Buhi WC, Wu GM, et al. Oviduct-specific glycopreotein modulates sperm-zona binding and improves efficiency of porcine fertilization in vitro. Biol Reprod, 2003, 69:828-834.
    McCormick SD. Hormonal control of gill Na~+, K~+-ATPase and chloride cell function. In: CM Wood and TJ Shuttleworth (Ed.), Cellular and Molecular Approaches to Fish Ionic Regulation, Academic Press, San Diego, 1995, p.285-316.
    McCoy DE, Guggino SE, Stanton BA. The renal cGMP-gated cation channel: its molecular structure and physiological role. Kidney Inter, 1995, 48:1125-1133.
    McCullough PA, Omland T, Maisel AS. B-type natriuretic peptides: a diagnostic breakthrough for clinicians. J Rev Cardiovasc Med, 2003, 4:72-80.
    McGee E, Spears N, Minami S, et al. Preantral ovarian follicles in serum-free culture: suppression of apoptosis after activation of the cyclic guanosine 3',5'-monophosphate pathway and stimulation of growth and differentiation by follicle-stimulating hormone. Endocrinology, 1997, 138:2417-2424.
    McVey M, Hill J, Howlett A, et al. Adenylyl cyclase, a coincidence detector for nitric oxide. J Biol Chem, 1999, 274:18887-18892.
    Mehats C, Andersen CB, Filopanti M, et al. Cyclic nucleotide phosphodiesterases and their role in endocrine cell signalling. Trends in End Metab, 2002, 13:29-35.
    Middendorff R, Davidoff MS, Behrends S, et al. Multiple roles of the messenger molecule cGMP in testicular function. Andrologia, 2000, 32:55-59.
    Middendorff R, Muller D, Mewe M, et al. The tunica albuginea of the human testis is characterized by complex contraction and relaxation activities regulated by cyclic GMP. J Clin Endocrinol Metab, 2002, 87:3486-3499.
    Miledi R, Woodward RM. Membrane currents elicited by prostaglandins, atrial natriutetic factor and oxytocin in follicle-enclosed Xenopus oocytes. J Physiol, 1989, 416:623-643.
    Milligan G. Techniques used in the identification and analysis of function of pertussis toxin-sensitive guanine nucleotide binding proteins. Biochem J, 1988, 255:1-13.
    Minamino N, Aburaya M, Kojima M, et al. Distribution of C-type natriuretic peptide and its mRNA in rat central nervous system and peripheral tissue. Biochem Biophys Res Commun, 1993, 197:326-335.
    Minna AK, Jarkko M, Keijo P, et al. Molecular heterogeneity has a major impact on the measurement of circulating N-terminal fragments of A- and B-type natriuretic peptides. J Clin Chem, 2004, 50:1576-1588.
    Moncada S, Palmer RM, Gryglewski RJ. Mechanism of action of some inhibitors of endothelium-derived relaxing factor. Proc Natl Acad Sci USA, 1986, 83:9146-9168.
    Morishita Y, Sano T, Ando K, et al. Microbial polysaccharide, HS-142-1 competitively and selectively inhibits ANP binding to its guanylyl cyclasecontaining receptor. Biochem Biophys Res Commun, 1991,176:949-957.
    Moya FJ, de Juan JA, Ripodas A, et al. Higher proportions of type C than of types A and B natriuretic peptide receptors exist in the rat ciliary body. Vis Res, 1998, 38:3833-3841.
    Mulay S, D'Sylva S, Varma DR. Inhibition of the aldosterone-suppressant activity of atrial natriuretic factor by progesterone and pregnancy in rats. Life Sci, 1993, 52:1121-1128.
    MUlsch A, Busse R, Liebau S, et al. LY 85583 interferes with the release of endothelium-derived relaxing factor and inhibits soluble guanylyl cyclase. J Pharmacol Exp Ther, 1988,247:283-288.
    Murayama M, Hayashi MAF, Ohi H, et al. Cloning and sequence analysis of a Bothrops jararaca cDNA encoding a precursor of seven bradykininpotentiating peptides and a C-type natriuretic peptide. Proc Natl Acad Sci USA, 1997, 94:1189-1193.
    Murthy KS , Teng BQ , Zhou H , et al. GMG(i-l) / G(i-2)-dependent signaling by single-transmembrane natriuretic peptide clearance receptor. Am J Physiol Gastrointest Liver Physiol, 2000, 278:G974-G980.
    Musah Al, Bloch JF, Baker SL, et al. Human atrial natriuretic peptide infusion and ovarian venous progesterone secretion in Yucatan micropigs. J Reprod Fertil, 1994,101:109-113.
    Nakagawa O, Ogawa Y, Itoh H, et al. Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy. Evidence for brain natriuretic peptide as an "emergency"cardiac hormone against ventricular overload. J Clin Invest, 1995, 96:1280-1287.
    Nakaoka H, Kitahara Y, Amano M, et al. Effects of 6-adrenergic receptor blockade on atrial natriuretic peptide in essential hypertension. Hypertension, 1987,10:221-225.
    Nally JE, Docherty CC, Clayton RA, et al. Bronchodilator and pre-protective effects of urodilatin in bovine bronchi in vitro: comparison with atrial natriuretic peptide. Br J Pharmacol 1995, 114:1391-1396.
    Nambi P, Whitman M, Aiyar N, et al. An activator of protein kinase C (phorbol dibutyrate) attenuates atrial-natriuretic-factor-stimulated cyclic GMP accumulation in smooth-muscle cells. Biochem J, 1987, 244:481-484.
    Nara M, Dhulipala PD, Ji GJ, et al. Guanylyl cyclase stimulatory coupling to K(Ca) channels. Am J Physiol Cell Physiol, 2000, 279:C1938-C1945.
    Neer EJ. Heterotrimeric G proteins: organizers of transmembrane signals. Cell, 1995, 80:249-257.
    Niwa K, Ohgoda O. Synergistic effect of caffeine and heparin on in-vitro fertilization of cattle oocytes matured in culture. Theriogenology, 1988, 30:733-741.
    Noubani A, Faroohi R, Gutkowska J. B-type natriuretic peptide receptor expression and activity are hormonally regulated in rat ovarian cells. Endocrinology, 2000,141:551-559.
    O'Grady SM, Field M, Nash NN, et al. Atrial natriuretic factor inhibits Na-K-Cl cotransporter in teleost intestine. Am J Physiol, 1985, 249:C531-C534.
    Ogawa Y, Nakao K, Mukoyama M, et al. Rat brain natriuretic peptide-tissue distribution and molecular form. Endocrinology, 1990,126:2225-2227.
    Ogawa Y, Tamura N, Chusho H, et al. Brain natriuretic peptide appears to act locally as an antifibrotic factor in the heart. Can J Physiol Pharmacol, 2001, 79:723-729.
    Okamoto T, Katada T, Murayama M, et al. A simple structure encodes G protein-activating function of the IGF-IIrmannose 6-phosphate receptor, Cell, 1990, 62:709-717.
    Olsiewski PJ, Beer WH. cAMP synthesis in rat oocyte. Dev Biol, 1983, 100:287-293.
    Olson KR. Hormone metabolism by the fish gill. Comp Biochem Physiol, 1998, 119A:55-65.
    Orstavik S, Solberg R, Tasken K. Molecular cloning, cDNA structure, and chromosomal localization of the human type Ⅱ cGMP-dependent protein kinase. Biochem Biophy Res Comm, 1996, 220:759-765.
    Orstavik S, Natarajan V, Tasken K, et al. Characterization of the human gene encoding the type Ⅰ alpha type Ⅰ betra cGMP-dependent protein kinase (PRKGI). Genomics, 1997, 42:311-318.
    Ostermeier GC, Dix DJ, Miller D, et al. Spermatozoal RNA profiles of normal fertile men. Lancet, 2002, 360:772-777.
    Ostermeier GC, Miller D, Huntriss JD, et al. Delivering spermatozoan RNA to the oocyte. Nature, 2004, 429:154.
    Palaparti A, Li Y, Anand-Srivastava M. B. Inhibition of atrial natriuretic peptide ANP C receptor expression by antisense oligodeoxynucleotides in A10 vascular smooth muscle cells is associated with attenuation of ANP-C-receptor-mediated inhibition of adenylyl cyclase. Biochem J, 2000, 346:313-320.
    Palmon SC, Williams MJ, Littleton-Kearney MT, et al. Estrogen increase cGMP in selected brain rgions and in cerebral microvessels. J Cereb Blood Flow Metab, 1998, 18:1248-1252.
    Panchenko MP, Joyce-Brady M, Starikova MG, et al. Atrial natriuretic peptide modulates alveolar type 2 cell adenylyl and guaylyl cyclases and inhibits surfactant secretion. Biochim Biophys Acta, 1998, 1403:115-125.
    Pandey KN, Nguyen HT, Li M, et al. Natriuretic peptide receptors-A negatively regulates mitogen-activated protein kinase and proliferation of mesangial cells: role of cGMP-dependent protein kinase. Biochem Biophys Res Commun, 2000, 271:374-379.
    Pandey KN, Orgebin-Crist MC. Atrial natriuretic factor in mammalian testis: immunological detection in spermatozoa. Biochem Biophys Res Commun, 1991, 180:437-444.
    Pandey KN, Osteen KG, Inagami T. Specific receptor-mediated stimulation of progesterone secretion and cGMP accumulation by rat atrial natriuretic factor in cultured human granulose-lugtein (GL)cells. Endocrinology, 1987, 121:1195-1197.
    Pang IH, Shade DL, Matsumoto S, et al. Presence of functional type B natriuretic peptide receptor in human ocular cells. Invest Ophthalmol Vis Sci, 1996, 37:1724-1731.
    Parrish JJ, Susko-Parrish JL, First NL. Effect of heparin and chondroitin sulfate on the acrosome reaction and fertility of bovine sperm in vitro. Theriogenology, 1986, 24:537-549.
    Patil RV, Han Z, Wax MB. Regulation of water channel activity of aquaporin 1 by arginine vasopressin and atrial natriuretic peptide. Biochem Biophys Res Commun, 1997, 238:392-396.
    Paz DA, Ruiz G, Casco VH, et al. Presence and release of immunoreaction atrial natriuretic peptide (ANP) in Bufo arenarum spermatozoa after HCG treatment. Biocell, 1996, 20:47-54.
    Paz DA, Ruiz G, Casco VH, et al. The presence of atrial natriurtic peptide (ANP) in spermatozoa of Bufo atrnarum and effects of GnRH. Gen Comp Endocrinol, 1993, 91:31-37.
    Pelletier G. Radiographic localization of atrial natriuretic factor receptors in the rat testis. J Androl, 1988, 9:352-355.
    Perreault T, Gutkowska J. Role of atrial natriuretic factor in lung physiology and pathology. Am J Respir Crit Care Med, 1995, 151:226-242.
    Petters RM, Wells KD. Culture of pig embryos. J Reprod Fertil (Suppl.), 1993, 48:61-73.
    Piao FL, Park SH, Hart JH, et al. Dendroaspis natriuretic peptide and its functions in pig ovarian granulosa cells. Regul Pept, 2004, 118:193-198.
    Piquette GN, LaPolt PS, Oikawa M, et al. Regulation of LH receptor messenger ribonucleic acid levels by gonadotropins, growth factors, and gonadotropin releasing hormone in cultured rat granulosa cells. Endocrinology, 1991, 128:2449-2456.
    Platz CC Jr, Wildt DE, Howard JG, et al. Electroejaculation and semen analysis and freezing in the giant panda (Ailuropoda melanoleuca). J Reprod Fertil, 1983, 67:9-12.
    Porter JG, Wang Y, Schwartz K, et al. Characterization of the atrial natriuretic peptide clearance receptor using a vaccinia virus expression vector. J Biol Chem, 1988, 263:18827-18833.
    Potter L R, Garbers DL. Protein kinase C-dependent desensitization of the atrial natriuretic peptide receptor is mediated by dephosphorylation. J Biol Chem, 1994, 269:14636-14642.
    Potvin W, Mulay S, Varma DR. Inhibition of the tocolytic activity of atrial natriuretic factor by progesterone and potentiation by progesterone receptor antagonist RU486 in rats. Br J Pharmacol, 1991, 104:379-384.
    Primakoff P, Myles DG. Penetration, adhesion, and fusion in mammalian sperm-egg interaction. Science, 2002, 296:2183-2185.
    Prochazka R, Nagyova E, Rimkevicova Z, et al. Lack of effect of oocytectomy on expansion of the porcine cumulus. J Reprod Fertil, 1991, 93:569-576.
    Racowsky C. Effect of forskolin on maintenance of meiotic arrest and stimulation of cumulus expansion, progesterone and cyclic AMP production by pig oocyte-cumulus complexes. J Reprod Fert, 1985, 74:9-21.
    Rademaker MT, Charles CJ, Espiner EA, et al. Combined inhibition of angiotensin Ⅱ and endothelin suppresses the brain natriutetic peptide response to developing heart failure. J Clin Sci (Lond), 2004, 106:569-576.
    Raidoo DM, Narotam PK, Dellen J, et al. Cellular orientation of atrial natriuretic peptide in the human brain. J Chem Neur, 1998, 14:207-213.
    Ratner A, Sanborn CR. Effect of endogenous LH secretion on ovarian cyclic AMP and cyclic GMP levels in the rat. Life Sci, 1980, 26:439-445.
    Ratner A. Effects of follicle stimulating hormone and LH upon cyclic AMP and cyclic GMP levels in rat ovaries in vitro. Endocrinology, 1976, 99:1496-1500.
    Richards AM, Lainchbury JG, Nicholls MG, et al. Dendroaspis natriuretic peptide: endogenous or dubious? Lancet, 2002, 359:5-6.
    Richards JS, Fitzpatrick SL, Clemens JW, et al. Ovarian cell differentiation: a cascade of multiple hormones signals and regulated genes. In: CW Bardin (ed.), Recent Progress in Hormone Research. San Diego: Academic Press, 1995, 50:223-254.
    Rogers J, Hughes RG, Matthews EK. Cyclic GMP inhibits protein kinase C-mediated secretion in rat pancreatic acini. J Biol Chem, 1988, 263:3713-3719.
    Roldan ER, Murase T, Shi QY. Exocytosis in spermatozoa in response to progesterone and zona pellucida. Science, 1994, 266:1578-1581.
    Rooney SA, Young SL. Mendelson CR. Molecular and cellular processing of lung surfactant, FASEB J, 1994, 8:957-967.
    Ropero AB, Fuentes E, Rovira JM, et al. Non-genomic actions of 17 beta-oestradiol in mouse pancreatic beta-cells are mediated by a cGMP-dependent protein kinase. J Physiol, 1999, 521:397-407.
    Rosenzweig A, Seidman CE. Atrial natriuretic factor and related peptide hormones. Annu Rev Biochem, 1991, 60:229-255.
    Rotem R, Paz GF, Homonnai ZT, et al. Ca~(2+)-independent induction of acrosome reaction by protein kinase C in human sperm. Endocrinology, 1992, 131:2235-2243.
    Rotem R, Zamir N, Keynan N, et al. Atrial natriuretic peptide induces acrosomal exocytosis of human spermatozoa. Am J Physiol, 1998, 274:E218-E223.
    Roth TL, Howard JG, Wildt DE. Zona pellucida piercing enhances zona penetration by spermatozoa from normospermic and teratospermic domestic cats. J Androl, 1994, 15:165-172.
    Ruskoaho H, Toth M, Ganten D, et al. The phorbol ester-induced atrial natriuretic peptide secretion is stimulated by forskolin and BAY K 8644 and inhibited by 8-bromo-cyclic GMP. Biochem Biophys Res Commun, 1986, 139:266-274.
    Ruskoaho H, Toth M, Unger T, et al. Atrial natriuretic peptide secretion: synergistic effect of phorbol ester and A23187. Biochem Biophys Res Commun, 1985, 133:581-588.
    Ruskoaho H. Atrial natriuretic peptide: Synthesis, release, and metabolism. Pharmacol Rev, 1992, 44:479-602.
    Russinova A, Mourdjeva M, Kyurkchiev S, et al. Immunohistochemical detection of atrial natriuretic factor (ANF) in different ovarian cell types. Endocr Regul, 2001, 35:81-89.
    Russinova A, Mourdjeva M, Valkova C, et al. Immunocytochemical localization of atrial natriuretic factor (ANF) in rat female reproductive tract: evidence for a potential hormonal regulation. Biol Cell, 2002, 94:91-98.
    Rybin VO, Uhal BD, Russo LA, et al. ADP ribosylation of type Ⅱ pulmonary epithelial cell G proteins. Am J Physiol, 1991, 260:L539-L547.
    Sagnella GA, Saggar-Malik AK, Buckley MG, et al. Association between atrial natriuretic peptide and cyclic GMP in hypertension and in chronic renal failure. Clinica Chimica Acta, 1998, 275:9-18.
    Saheki T, Shimonaka M, Uchida K, et al. Immunochemical and biochemical distinction of subtypes of atrial natriuretic peptide receptor. J Biochem, 1989, 106:627-632.
    Saijonmaa O, Fyhrquist F. Upregulation of angiotensin converting enzyme by atrial natriuretic peptide and cyclic GMP in human endothelial cells. Cardiovascular research, 1998, 40:206-210.
    Sakata J, Kangawa K, Matsuo H. Identification of new atrial natriuretic peptides in frog heart. Biochem Biophys Res Commun, 1988, 155:1338-1345.
    Sakuta H, Okamoto K. Atrial natriuretic factor potentiates glibenclamide-sensitive K+ currents via the activation of receptor guanylate cyclase in follicle-enclosed Xenopus oocytes. Tandai M Eur J Pharmacol, 1994, 267:281-287.
    Salustri A, Yanagishita M, Hascall VC. Mouse oocytes regulate hyaluronic acid synthesis and mucification by FSH-stimulated cumulus cells. Dev Biol, 1990,138:26-32.
    Salustri A, Yanagishita M, Underhill CB, et al. Localization and synthesis of hyaluronic acid in the cumulus cells and mural granulosa cells of the preovulatory follicle. Dev Biol, 1992,151:541-551.
    Samson WK. Atrial natriuretic factor inhibits dehydration and hemorrhage-induced vasopressin release. Neuroendocrinology, 1985, 40:277-279.
    Samuelsson-Almen M, Nilsson SFE, Maepea O, et al. Effects of atrial natriuretic factor (ANF) onintraocular pressure and aqueous humour flow in the cynomolgus monkey. Exp Eye Res, 1991, 53:253-260.
    Sanchez-Ferrer CF, Burnett JC Jr, Lorenz RR, et al. Possible modulation of release of atrial natriuretic factor byendothelium-derived relaxing factor. Am J Physiol, 1990, 259:H982-H986.
    Sandberg K, Bor M, Ji H, et al. Atrial natriuretic factor activates cyclic adenosine 3',5'-monophosphate phosphodiesterase in Xenopus laevis oocytes and potentiates progesterone-induced maturation via cyclic guanosine 5'-monophosphate accumulation. Biol Reprod, 1993, 49:1074-1082.
    Sanders MM, Midgley AR Jr. Cyclic nucleotides can induce LH receptors in cutured granulose cells. Edocrinology, 1983, 112:1382-1388.
    Savoie P, de Champlain J, Anand-Srivastava MB. C-type natriuretic peptide and brain natriuretic peptide inhibit adenylyl cyclase activity: interaction with ANF-R2rANP-C receptors. FEBS Lett, 1995, 370:6-10.
    Scheide JI, Zudunaisky JA. Effect of atriopeptin II on isolated opercular epithelium of Fundulus heteroclitus. Am J Physiol, 1988, 254:R27-R32.
    Schirger JA, Heublein DM, Chen HH, et al. Presence of Dendroaspis natriuretic peptide-like immunoreactivity in human plasma and its increase during human heart failure. Mayo Clin Proc, 1999, 74:126-130.
    Schoevers EJ, Kidson A, Verheijden JH, et al. Effect of follicle-stimulating hormone on nuclear and cytoplasmic maturation of sow oocytes in vitro. Theriogenology, 2003, 59:2017-2028.
    Schofield JP, Jones DS, Forrest Jr JN. Identification of C-type natriuretic peptide in the heart of spiny dogfish Squalus acanthias. Am J Physiol, 1991, 261:F734-F739.
    Schultz HD, Steele MK, Gardner DG. Central administration of atrial peptide decreases sympathetic outflow in rats. Am J Physiol, 1990, 258:R1250-R1256.
    Schultz R, Montgomery R, Belanoff J. Regulation of mouse oocyte meiotic maturation: implication of a decrease in oocyte cAMP and protein dephosphorylation in commitment to resume meiosis. Dev Biol, 1983, 97:264-273.
    Schulz S, Waldman SA. The guanylyl cyclase family of natriuretic peptide receptors. Vitamins and Hormones, 1999, 57:123-151.
    Schumacher H, Muller D, Mukhopadhyay AK. Stimulation of testosterone production by atrial natriuretic peptide in isolated mouse Leydig cells results from a promiscuous activation of cyclic AMP-dependent protein kinase by cyclic GMP. Mol Cell End, 1992, 90:47-52.
    Schweitz H, Vigne P, Moinier D, et al. A new member of the natriuretic peptide family is present in the venom of the green mamba (Dendroaspis angusticeps). J Biol Chem, 1992, 267:13928-13932.
    Seamon KB, Daly JW. Forskolin: a unique diterpene activator of cAM generating systems. J Cyc Nucleotide Res, 1981, 7:201-224.
    Shi H, Segaloff DL. A role for increased lutropin/choriogonadotropin receptor (LHR) gene in granulose cells. Mol Endocrin, 1995, 9:734-744.
    Shimizu T, Katsuura G, Nakamura M, et al. Effect of intracerebroventricular atrial natriuretic polypeptide on blood pressure and urine production in rats. Life Sci, 1986, 39:1263-1270.
    Silva P, Solomon RJ, Epstein FH. Mode of activation of salt secretion by C-type natriuretic peptide in the shark rectal gland. Am J Physiol 1999, 277: R1725-R1732.
    Silvestroni L, Palleschi S, Guglielmi R, et al. Identification and localization of atrial natriuretic factor receptors in human spermatozoa. Arch Androl, 1992, 28:75-82.
    Sirard MA. Temporary inhibition of meiosis resumption in vitro by adenylate cyclase stimulation in immature bovine oocytes. Theriogenology, 1990, 33:757-767.
    Sirotkin AV, Mlyncek J, Lavrineik J, et al. The ability of steroid hormones to control cAMP and cGMP production by human granulose cells in culture. Cell Signal, 1995, 7:61-65.
    Smyth EM, Keenan AK. The vascular ANF-C receptor: role in atrial peptide signaling. Cell Signal, 1994, 61:125-133.
    Snyder GD, Holmes RW, Bates JN, et al. Nitric oxide inhibits aromatase activity:mechanisms of action. J Steriod Biochem Mol Biol, 1996, 58:63-69.
    Solomon R, Protter A, McEnroe G, et al. C-type natriuretic peptides stimulates chloride secretion in the rectal gland of Squalus acanthias. Am J Physiol, 1992, 264:R707-R711.
    Soualmia H, Barthelemy C, Eurin J, et al. Role of nitric oxide on atrial natriuretic peptide release induced by angiotensin Ⅱ in superfused rat atrial tissue. Regul Pept, 2001, 98:105-110.
    Spindler RE, Howard JG, Huang Y, et al. Cryopreservation has no impact on subsequent sperm capacitation in vitro in the giant panda. Biol Reprod, 2001, 64 (Suppl):522.
    Spindler RE, Huang Y, Howard JG, et al. Acrosomal integrity and capacitation are not influenced by sperm cryopreservation in the giant panda. Reproduction, 2004, 127:547-556.
    Stamler JS. Redox signaling: nitrosylation and related target interactions of nitric oxide. Cell, 1994, 78:931-936.
    Steegers EA, Hollanders JM, Jongsma HW, et al. Atrial natriuretic peptide and progesterone in ovarian follicular fluid. Gynecol Obstet Invest, 1990, 29:185-187.
    Strauss JF, Golos TG, Silavin SL, et al. Involvement of cyclic AMP in the functions of granulose and luteal cells:regulation of steroidogenesis. Prog Clin Biol Res, 1988, 267:177-200.
    Stults JT, O'Connell KL, Garcia C, et al. The disulfide linkages and glycosylation sites of the human natriuretic peptide receptor-C homodimer. Biochemistry, 1994, 33:11372-11381.
    Su YQ, Denegre JM, Wigglesworth K, et al. Oocyte-dependent activation of mitogen-activated protein kinase (ERK1/2) in cumulus cells is required for the maturation of the mouse oocyte-cumulus cell complex. Dev Biol, 2003, 263:126-138.
    Su YQ, Rubinstein S, Luria A, et al. Involvement of mek-mitogen-activated protein kinase pathway in follicle-stimulating hormone-induced but not spontaneous meiotic resumption of mouse oocytes. Biol Reprod, 2001, 65:358-365.
    Su YQ, Wigglesworth K, Pendola FL, et al. Mitogen-activated protein kinase activity in cumulus cells is essential for gonadotropin-induced oocyte meiotic resumption and cumulus expansion in the mouse. Endocrinology, 2002, 143:2221-2232.
    Su YQ, Xia GL, Byskov AG, et al. Protein kinase C and intracellular calcium are involved in follicle-stimulating hormone-mediated meiotic resumption of cumulus cell-enclosed porcine oocytes in hypoxanthine-supplemented medium. Mol Reprod Dev, 1999, 53:51-58.
    Sudoh T, Kangawa K, Minamino N, et al. A new natriuretic peptide in porcine brain. Nature, 1988, 332:78-81.
    Sudoh T, Minamino N , Kangawa K, et al. C-type natriuretic peptide (CNP): a new member of natriuretic peptide family identified in porcine brain. Biochem Biophys Res Commun, 1990, 168:863-870.
    Suga SI, Nakao K, Hosoda K, et al. Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide. Endocrinology, 1992, 130:229-239.
    Sugamori T, Sakane T, Ishibashi Y, et al. Atrial natriuretic peptide has nitric oxide-mediated vasodilatory effect? Circulation, 1999, 100:438.
    Sugimoto T, Kikkawa R, Haneda M, et al. Atrial natriuretic peptide inhibits endothelin-1-induced activation of mitogen-activated protein kinase in cultured rat mesangial cells. Biochem Biophys Res Commun, 1993, 195:72-78.
    Sumii K, Sperelakis N. cGMP-dependent protein kinase regulation of the L-type Ca~(2+) current in rat ventricular myocytes. Circul Res, 1995, 77:803-812.
    Sun Q, Liu H, Li X, et al. The role of Ca~(2+) and protein kinase in the acrosome reaction of giant panda (Ailuropoda melanoleuca.) spermatozoa. Theriogenology, 1996, 46:359-367.
    Sun QY, Breitbart H, Schatten H. Role of the MAPK cascade in mammalian germ cells. Reprod Fertil Dev, 1999, 11:443-450.
    Sundsfjord JA, Forsdahl F, Thibault G. Physiological levels of immunoreactive ANH-like peptides in human follicular fluid. Acta Endocrinol (Copenh), 1989, 121:578-580.
    Suzuki R, Takahashi A, Hazon N, et al. Isolation of high-molecular-weight C-type natriuretic peptide from the heart of a cartilaginous fish European dogfish. Scyliorhinus cannicula FEBS Lett, 1991, 282:321-325.
    Suzuki R, Takahashi A, Takei Y. Different molecular forms of C-type natriuretic peptide isolated from the brain and heart of an elasmobranch. Triakis scyllia J Endocrinol, 1992,135:317-323.
    Suzuki R, Togashi K, Ando K, et al. Distribution and molecular forms of C-type natriuretic peptide in plasma and tissues of a dogfish. Triakis scyllia Gen Comp Endocrinol, 1994, 96:378-384.
    Tafoya MA, Chen YJ, LaPolt PS. Activation of soluble guanylyl cyclase inhibits estradiol production and cyclic AMP accumulation from cultured rat granulose cells. Program 83rd Ann Meet End Societ, 2001, abstract:354.
    Takei Y, Flik G, Hirose S. Interaction of the natriuretic peptide system and the rennin-angiotensin system in eel osmoregulation. In: EW Roubos, S Wendelaar Bonga, H Vaudry and A de Loof (Ed.), Recent Developments in Comparative Endocrinology and Neurobiology, Shaker Publishing BV, Maastricht, 1999, p.144-148.
    Takei Y, Kaiya H. Antidiuretic effect of eel ANP infused at physiological doses in seawateradapted eels. Anguilla japonica Zool Sci, 1998, 15:399-404.
    Takei Y, Takahashi A, Watanabe TX, et al. A novel natriuretic peptide isolated from eel cardiac ventricle. FEBS Lett, 1991, 282: 317-320.
    Takei Y, Takano M, Itahara Y, et al. Rainbow trout ventricular natriuretic peptide: isolation, sequencing and determination of biological activity. Gen Comp Endocrinol, 1994a, 96:420-426.
    Takei Y, Ueki M, Nishizawa T. Eel ventricular natriuretic peptide: cDNA cloning and mRNA expression. J Mol Endocrinol, 1994b, 13:339-345.
    Takei Y. Comparative physiology of body fluid regulation in vertebrates with special reference to thirst regulation. Jpn J Physiol, 2000b, 50:171-186.
    Takei Y. Does the natriuretic peptide system exist throughout the animal and plant kingdom. Comp Biochem Physiol B Biochem Mol Biol, 2001, 129:559-573.
    Takei Y. Structural and functional evolution of the natriuretic peptide system in vertebrates. Int Rev Cytol, 2000a, 194:1-66.
    Talbot P, Chacon RS. A triple stain technique for evaluating normal acrosome reaction of human sperm. J Exp Zool, 1981, 215:201-208.
    Tamura N, Ogawa Y, Yasoda A, et al. Two cardiac peptide genes atrial natriuretic peptide and brain natriuretic peptide are organized in tandem in the mouse and human genomes. J Mol Cell Cardiol, 1996, 28:1811-1815.
    Tao H, Zhang LM, Castresana MR et al. C-natriuretic peptide but not atrial natriuretic peptide increases cyclic GMP in cerebral arterial smooth muscle cells. Life Sci, 1995, 56:2357-2365.
    Tao Y, Xia GL, Bo SM, et al. Nitric oxide exerts different functions on porcine oocytes cultured in different models, which is affected by beta-mercaptoethanol. Asian-Aust J Anim Sci, 2004, 17:317-324.
    Tatemoto H, Okuda T, Sogo N, et al. Male pronuclear formation and blastocyst formation are improved by supplementation of ascorbic acid 2-O-a-glucoside during in vitro maturation culture of denuded porcine oocytes. J Reprod Dev, 2001, 47:329-339.
    Taussig R, Gilman AG. Mammalian membrane-bound adenylyl cyclases. J Biol Chem, 1995, 270:1-4.
    Telegdy G, Adamik A, Glover V. The action of isatin (2,3-dioxoindole) an endogenous indole on brain natriuretic and C-type natriuretic peptide-induced facilitation of memory consolidation in passive-avoidance learning in rats. Brain Res Bull, 2000, 53:367-370.
    Tervonen V, Arjamaa O, Kokkonen K, et al. A novel cardiac hormone related to A-, B- and C-type natriuretic peptides. Endocrinology, 1998, 139:4012-4025.
    Thirstrup S, Nielsen-Kudsk JE, Mellemkjaer S. Involvement of Kq channels in the relaxant effect of vasoactive intestinal peptide and atrial natriuretic peptide in isolated guinea-pig trachea. Eur J Pharmacol, 1997, 319:253-259.
    Thomas RE, Armstrong DT, Gilchrist RB. Differential effects of specific phosphodiesterase isoenzyme inhibitors on bovine oovyte meiotic maturation. Dev Biol, 2002, 244:215-225.
    Tobai H, Nishiya I. Nitric oxide mediates inhibitory effect of interleukin-Ⅰ beta on estrogen production in huaman granulose-luteal cells. J Obst Gynaec Res, 2001, 27:53-59.
    Togashi K, Kameya T, Kurosawa T, et al. Concentrations and molecular forms of C-type natriuretic peptide in brain and cerebrospinal fluid. Clin Chem, 1992, 38:2136-2139.
    Toop T, Donald JA, Evans DH. Localisation and characteristics of natriuretic peptide receptors in the gills of the Atlantic hagfish Myxine glutinosa Agnatha. J Exp Biol, 1995a, 198:117-126.
    Toop T, Donald JA, Evans DH. Natriuretic peptide receptors in the kidney and the ventral and dorsal aortae of the Atlantic hagfish Myxine glutinosa Agnatha. J Exp Biol, 1995b, 198:1875-1882.
    TOrnell J, Carlsson B, Billig H. Atrial natriuretic peptide inhibits spontaneous rat oocyte maturation. Endocrinology, 1990, 126:1504-1508.
    Tsafriri A, Chun SY, Zhang R, et al. Oocyte maturation involves compartmentalization and opposing changes of cAMP levels in follicular somatic and germ cells: studies using selective phosphodiesterase inhibitors. Dev Biol, 1996, 178:393-402.
    Tsuchida T, Takei Y. Effects of homologous atrial natriuretic peptide on drinking and plasma angiotensin Ⅱ level in eels. Am J Physiol, 1998, 275:R1605-R1610.
    Tsukagoshi H, Shimizu Y, Kawata T, et al. Atrial natriuretic peptide inhibits tumor necrosis factor-alpha production by interferon-gamma-activated macrophages via suppression of p38 mitogen-activated protein kinase and nuclear factor-kappa B activation. Regul Pept, 2001, 99:21-29.
    Usuki S, Saitoh T, Saitoh M, et al. Endothelin-renin-angiotensin-atrial natriuretic peptide system in ovaries: an intraovarian ERAANP system. J Cardiovasc Pharmacol, 1993, 22:207-210.
    Usuki S, Tanaka J, Kawakura Y, et al. A proposal of ovarian ERAANPS (endothelin-reninangiotensin-atrial natriuretic peptide system) and effects of tokishakuyakusan, keishibukuryogan, shakuyakukanzoto and unkeito on the ERAANPS. Am J Chin Med, 1992, 20:65-74.
    Van Der Zander K, Houben AJ, Kroon AA, et al. Nitric oxide and potassium channels are involved in brain natriuretic peptide induced vasodilatation in man. J Hypertens, 2002, 20:493-511.
    Van Voorhis BJ, Dunn MS, Snyder GD, et al. Nitric oxide: an autocrine regulator of human granulose-luteal cell steroidogenesis. Endocrinology, 1994, 135:1799-1806.
    Van Voorhis BJ, Moore K, Strijbos P, et al. Expression and localization of inducible and endothelial nitric oxide synthase in the rat ovary. J Clin Invest, 1995, 96:2719-2726.
    Vanderhyden BC, Caron PJ, Buccione R, et al. Developmental pattern of the scretion of cumulus expansio-enabling factor by mouse oocyte and the role oocyte in promoting granulose cell differentiation. Develop Biol, 1990, 140:307-317.
    Vanderhyden BC. Species differences in the regulation of cumulus expansion by an oocyte-secreted factor(s). J Reprod Fertil, 1993, 98:219-227.
    Vesely DL, Douglass MA, Dietz JR, et al. Three peptides from the atrial natriuretic factor prohormone amino terminus lower blood pressure and produce a diuresis, natriuresis and/or kaliuresis in humans. Circulation, 1994, 90:1129-1140.
    Vesely DL, Norsk P, Winters CJ, et al. Increased release of the N-terminal and C-terminal portions of the prohormone of atrial natriuretic factor during immersion-induced central hypervolemia in normal humans. Proc Soc Exp Biol Med, 1989, 192:230-235.
    Vieira MAR, Gao M, Nikonova LN, et al. Molecular and cellular physiology of the dissociation of atrial natriuretic peptide from guanylyl cyclase A receptors. J Biol Chem, 2001, 276:36438-36445.
    Vollmar AM, Mytzka C, Arendt RM, et al. Atrial natriuretic peptide in bovine corpus luteum. Endocrinology, 1988, 123:762-767.
    Vollmar AM, Schulz R. Atrial natriuretic peptide inhibits nitric oxide synthesis in mouse macrophages. Life Sci, 1995, 56:149-155.
    Wang WH, Niwa K, Okuda K. In-vitro penetration of pig oocytes matured in culture by frozen-thawed ejaculated spermatozoa. J Reprod Fertil, 1991, 93:491-496.
    Wang YJ, Ge W. Involvement of cyclic adenosine 3',5'-monophosphate in the differential regulation of activin βA and βB expression by gonadotropin in the zebrafish ovarian follicle cells. Endocrinology, 2003, 144:491-499.
    Wassarman PM, Jovine L, Litscher ES. A profile of fertilization in mammals. Nat Cell Biol, 2001, 3:E59-E64.
    Wassarman PM. Early events in mammalian fertilization. Annu Rev Cell Biol, 1987, 3:109-142.
    Watanabe H, Suzuki K, Takagi K, et al. Mechanism of atrial natriuretic polypeptide and sodium nitroprusside-induced relaxation in guinea-pig tracheal smooth muscle. Arzneim Forsch, 1990, 40:771-776.
    Weyand I, Godde M, Frings S, et al. Cloning and functional expression of a cyclic-nucleotide-gated channel from mammalian sperm. Nature, 1994, 368:859-863.
    Whalin ME, Scammell JG, Strada SJ, et al. Phosphodiesterase Ⅱ, the cGMP-avtivatable cyclic nucleotide phosphodiesterase, regulates cyclic AMP metabolism in PC12 cells. Mol Phoram, 1991, 39:711-717.
    Woodard GE, Rosado JA, Brown J. Dendroaspis natriuretic peptide-like immunoreactivity and its regulation in rat aortic vascular smooth muscle. Peptides, 2002, 23:23-29.
    Woods RL. Contribution of the kidney to metabolic clearance of atrial natriuretic peptide. Am J Physiol, 1988, 255:E934-E941.
    Wright JR, Dobbs LG. Regulation of pulmonary surfactant secretion and clearance, Annu Rev Physiol, 1991, 53:395-414.
    Wu GM, Sun OY, Mao J, et al. High developmental competence of pig oocytes after meiotic inhibition with a specific M-phase promoting factor kinase inhibitor, butyrolactone Ⅰ. Biol Reprod, 2002, 67:170-177.
    Xia GL, Byskov AG, Andersen YC. Cumulus cells secrete a meiosis-inducing substance by stimulation with forskolin and dibutyric cyclic adenosine monophosphate. Mol Reprod Dev, 1994, 39:17-24.
    Xia GL, Kikuchi K, Noguchi J, et al. Short time priming of pig cumulus-oocyte complexes with FSH and forskolin in the presence of hypoxanthine stimulates cumulus cells to secrete a meiosis-activating substance. Theriogenology, 2000, 53:1807-1815.
    Xie H, Xia G, Byskov AG, et al. Roles of gonadotropins and meiosis-activating sterols in meiotic resumption of cultured follicle-enclosed mouse oocytes. Mol Cell End, 2004, 218:155-163.
    Yamamoto K, Ikeda U, Shimada K. Natriuretic Peptides Modulate Nitric Oxide Synthesis in Cytokine-stimulated Cardiac Myocytes. J Mol Cell Cardiol, 1997, 29:2375-2382.
    Yanagimachi R, Lopata A, Odom CB, et al. Retention of biologic characteristics of zona pellucida in highly concentrated salt solution: the use of salt-stored eggs for assessing the fertilizing capacity of spermatozoa. Fertil Steril, 1979, 31:562-574.
    Yanagimachi R, Usui N. Calcium dependence of the acrosome reaction and activation of guinea pig spermatozoa. Exp Cell Res, 1974, 89:161-174.
    Yanagimachi R. Mammalian fertilization. In: E Knobil and JD Neil (Ed.), The physiology of reproduction, New York: Raven, 1994a, p.189-317.
    Yanagimachi R. Mammalian fertilization. In: E. Knobil and JD Neil (Ed.), The physiology of Reproduction, New York: Raven, 1994b. p.152-162.
    Yanagimachi R. Mechanisms of fertilization in mammals. In: L Mastroianni and J Biggers (Ed.), Fertilization and Embryonic Development In Vitro. New York: Plenum Publishers, 1981, p.81-182.
    Yoshida M, Ishizaki Y, Kawagishi H. Blastocyst formation by pig embryos resulting from in-vitro fertilization of oocytes matured in vitro. J Reprod Fertil, 1990, 88:1-8.
    Yoshimoto T, Naruse M, Irie K, et al. β-Adrenoceptor antagonist propranolol potentiates hypotensive action of natriuretic peptides. Eur J Pharm, 1998, 351:61-66.
    Zamir N, Barkan D, Keynan N, et al. Atrial natriuretic peptide induces an acrosomal exocytosis in bovine spermatozoa. Am J Physiol, 1995, 269:E216-E221.
    Zamir N, Riven-Kreitman R, Manor M, et al. Atrial natriuretic peptide attracts human spermatozoa in vitro. Biochem Biophys Res Commun, 1993, 197:116-212.
    Zhang X, Armstrong DT. Effects of follicle-stimulating hormone and ovarian steroids during in vitro meiotic maturation on fertilization of rat oocytes. Garnet Resear, 1989, 23:267-277.
    Zhao XM, Song XX, Kawai Y, et al. Penetration in vitro of zona-free pig oocytes by homologous and heterologous spermatozoa. Theriogenology, 2002, 58:995-1006.
    Zhao YL, Wang JH, Cheng CP. Effect of ANP on estradiol and progesterone production by rat ovarian cells. Sheng Li Xue Bao, 1991, 43:580-583.
    Zhou HL, Newsholme SJ, Torphy TJ. Agonist-related differences in the relationship between cAMP content and protein kinase activity in canine trachealis. J Pharmacol Exp Ther, 1992, 261:1260-1267.
    卜淑敏.一氧化氮调控小鼠卵母细胞成熟的信号转导机制的研究:[博士学位论文].北京:中国农业大学,2003.
    陈明辉,黄显奋.C型利钠肽及其受体的结构和功能.中国药理学通报,1998,14:5～8.
    陈习中.心脏分泌的激素—心钠素.生物学通报,1995,30(10):1～4.
    陈永生,孙宗钦.ANP RIA在糖尿病肾病中的临床应用.放射免疫学杂志,2004,17(2):127～128.
    戴山林,黄茂,王宏,等.哮喘豚鼠内皮素、心钠素含量的变化及心钠素对内皮素含量的影响.中国病理生理杂志,2000,16(10):906～908.
    苗新芳,戚好文,李志超.ANP对急性肺损伤大鼠AQP1表达的影响.第四军医大学学报,2003,24(24):2241～2243.
    泰宁,李育阳.心钠素的分子生物学.国外医学分子生物学分册,1988,10(2):51～56.
    王跃民,裴建明,朱妙章,等.C型钠尿肽的扩血管作用及机制.中国应用生理学杂志,2001,17(2):174～177.
    徐丽,陈兰英.利钠肽结构、受体的生理和病理作用.中国病理生理杂志,2004,20(8):1517～1521.
    张更荣,陈电容.充血性心力衰竭患者血浆内皮素与心钠素关系的探讨.宁波医学,1998,10(1):1～2.
    张汉原.心钠素研究.生命的化学,1993,13(1):262～268.
    张培荣,王宇航,黄彦生.N-心钠素在无症状性心力衰竭中的诊断价值.临床荟萃,2001,16(6):244～246.
    周琰,陶青,潘柏申.B型利尿肽在心脏疾病中的应用.诊断学理论与实践,2004,3(5):376～381.