摘要
从狗脊(Woodwardia japonica (L.f.) Sm.)中分离得到六个化合物，经解析，分别鉴定为：山柰素-3-O-α-L-(4-O-乙酰基)鼠李糖基-7-O-α-L-鼠李糖甙(Ⅰ)、山柰素-3-O-α-L-鼠李糖基-7-O-α-L-鼠李糖甙(Ⅱ)、狗脊蕨酸(Ⅲ)、β-谷甾醇(Ⅳ)、胡萝卜甙(Ⅴ)，β-谷甾醇-3-O-α-L-(6-O-正十六酰基)葡萄糖甙(Ⅵ)。MS-MS检测并鉴定化合物一个：β-谷甾醇-3-O-α-L-(6-O-正十五酰基)葡萄糖甙(Ⅶ)。以上化合物均系首次从该植物中获得，化合物Ⅶ为新化合物。另有六个化合物，未能分离得到化合物单体，经解析，可以确定其中五个化合物的结构物，分别为：山柰素-7-O-α-L-鼠李糖甙(Ⅷ-Ⅰ)、山柰素-3-O-α-L-(3,4-O-2乙酰基)鼠李糖甙(Ⅷ-Ⅱ)、山柰素-3-O-α-L-鼠李糖甙(Ⅷ-Ⅳ)、山柰素-3-O-α-L-(3-O-乙酰基)鼠李糖甙(Ⅷ-Ⅴ)、山柰素-3-O-α-L-(4-O-乙酰基)鼠李糖甙(Ⅷ-Ⅵ)。
Chemical study of Woodwardia japonica afforded the new p-sitosterol-3-O-α-L-(6-O-pentadecanoyl) glycoside (Ⅶ) together with six known compounds, kaempferol 3-O-α-L-(4-O-acetyl)rhamnopyranoside-7-O-α-L-rhamnopyranoside (Ⅰ), kaempferol 3-O-α-L-rhamnopyranoside-7-O-α-L-rhamnopyranoside (Ⅱ), woodwardinic acid (Ⅲ), β-sitosterol (Ⅳ), daucosterol (Ⅴ), β-sitosterol-3-O-α-L-(6-O- hexadecanoyl ) glycoside (Ⅵ). The structure of these compounds was determined by spectroscopic methods. All of these compounds were isolated from Woodwardia japonica for the first time. Five compounds were identified but not isolated as monomeric compounds. They are kaempferol 7-O-α-L-rhamnopyranoside (Ⅷ-Ⅰ),kaempferol 3-O-α-L-(3,4-O-diacetyl) rhamnopyranoside (Ⅷ-Ⅱ) , kaempferol 3-O-α-L-rhamnopyranoside (Ⅷ-Ⅳ). kaempferol 3-O-α-L-(3-O-acetyl)rhamnopyranoside (Ⅷ-Ⅴ), kaempferol 3-O-α-L-(4-O-acetyl) rhamnopyranoside (Ⅷ-Ⅵ).
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