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Elsevier电子期刊(2182)

在“Elsevier电子期刊”中，命中：2,182条，耗时：小于0.01 秒

在所有数据库中总计命中：2,182条

1.Lipophilicity estimation and characterization of selected steroid derivatives of biomedical importance applying RP HPLC

作者：Lidija R. Jevrić^a ; Milica Ž. Karadžić^a ; ^{mkaradza@uns.ac.rs} ; Anamarija I. Mandić^b ; Sanja O. Podunavac Kuzmanović^a ; Strahinja Z. Kovačević^a ; Andrea R. Nikolić^c ; Aleksandar M. Oklje&scaron ; a^c ; Marija N. Sakač^c ; Katarina M. Penov Ga&scaron ; i^c ; Srđan Z. Stojanović^d

关键词：Drug candidates ; Chemometrics ; Lipophilicity ; Liquid chromatography ; Quantitative structure retention relationships

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：2017

2.Development of a simple proton nuclear magnetic resonance-based procedure to estimate the approximate distribution coefficient at physiological pH (log D_7.4): Evaluation and comparison to existing practices

作者：E. Johanna L. Sté ; en^a ; ¹ ; Nils Nyberg^a ; ¹ ; Szabolcs Lehel^b ; Valdemar L. Andersen^b ; Pantaleo Di Pilato^c ; Gitte M. Knudsen^d ; Jesper L. Kristensen^a ; Matthias M. Herth^a ; ^b ; ^d ; ^{matthias.herth@sund.ku.dk}

关键词：Lipophilicity ; Distribution coefficient ; Log ; D7.4 ; NMR

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

3.Assessment of the pharmacokinetic profile of novel s-triazine derivatives and their potential use in treatment of Alzheimer's disease

作者：Jovana Trifunović ; ^{jovanatrifunovic@gmx.com} ; ^{jovanatrifunovic@uns.ac.rs} ; Vladan Borčić ; Sa&scaron ; a Vukmirović ; Momir Mikov

关键词：Alzheimer's disease ; s-Triazine ; Lipophilicity ; Molecular docking ; QSAR

刊名：Life Sciences

出版年：2017

4.A multi-endpoint matched molecular pair (MMP) analysis of 6-membered heterocycles

作者：George Chang^a ; ^{george.c.chang@pfizer.com} ; Kim Huard^b ; Gregory W. Kauffman^a ; Antonia F. Stepan^c ; Christopher E. Keefer^a

关键词：Matched molecular pair ; Multiparameter optimization ; Log ; D lipophilicity ; Human liver microsomal metabolism ; P-gp efflux ; Passive membrane permeability

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

5.Physico-chemical profiling of semisynthetic opioids

作者：Ká ; roly Mazá ; k ; ^{mazak.karoly@pharma.semmelweis-univ.hu} ; Sá ; ndor Hosztafi ; Má ; rta Kraszni ; Bé ; la Noszál

关键词：Nalorpine ; Nalbuphine ; Dihydromorphine ; Hydromorphone ; Lipophilicity ; Microscopic protonation constant

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：2017

6.Fluorophilicity and lipophilicity of fluorinated rhodamines determined by their partition coefficients in biphasic solvent systems

作者：Mark Jbeily ; Jö ; rg Kressler ; ^{joerg.kressler@chemie.uni-halle.de}

关键词：Fluorophilicity ; Fluorinated rhodamines ; Partition coefficients ; Giant unilamellar vesicles

刊名：Journal of Fluorine Chemistry

出版年：2017

7.Brain uptake and metabolism of the endocannabinoid anandamide labeled in either the arachidonoyl or ethanolamine moiety

作者：Kun Hu ; Shilpa Sonti ; Sherrye T. Glaser ; Richard I. Duclos Jr ; Samuel J. Gatley ; ^{s.gatley@neu.edu}

关键词：Endocannabinoid ; Radiotracer ; Lipophilicity

刊名：Nuclear Medicine and Biology

出版年：2017

8.Antiproliferative activity of amino substituted benzo[b]thieno[2,3-b]pyrido[1,2-a]benzimidazoles explored by 2D and 3D cell culture system

作者：Nata&scaron ; a Perin^a ; Kristina Bobanović^b ; Ivo Zlatar^c ; Dubravko Jelić^c ; Vanja Kelava^d ; Sanja Ko&scaron ; trun^d ; Vesna Gabelica Marković^d ; Karmen Braj&scaron ; a^c ; ^{karmen.brajsa@glpg.com} ; Marijana Hranjec^a ; ^{mhranjec@fkit.hr}

关键词：Antiproliferative activity ; benzo[b]thieno[2 ; 3-b]pyrido[1 ; 2-a]benzimidazoles ; 2D and 3D in vitro cytotoxicity assay ; Lipophilicity ; Physico-chemical properties

刊名：European Journal of Medicinal Chemistry

出版年：2017

9.Prediction and mechanism elucidation of analyte retention on phospholipid stationary phases (IAM-HPLC) by in silico calculated physico-chemical descriptors

作者：Giacomo Russo^a ; ^{giacomo.russo@unina.it} ; Lucia Grumetto^a ; Francesco Barbato^a ; Giulio Vistoli^b ; Alessandro Pedretti^b

关键词：Immobilized artificial membrane ; Prediction of phospholipid affinity ; IAM-HPLC ; Quantitative structure-property relationship models ; Biochromatography

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

10.Tactics for preclinical validation of receptor-binding radiotracers

作者：Susan Z. Lever^a ; ^b ; ^{levers@missouri.edu} ; Kuo-Hsien Fan^a ; John R. Lever^c ; ^d ; ^{leverj@health.missouri.edu}

关键词：Imaging ; Validation ; Radiopharmaceutical ; Radiotracer ; Radiopharmacology ; Sigma receptor

刊名：Nuclear Medicine and Biology

出版年：2017

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