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在“
Elsevier电子期刊
”中,
命中:
75,499
条,耗时:小于0.01 秒
在所有数据库中总计命中:
129,443
条
1.
Synthesis of novel glycosyl-1,2,3-1H-triazolyl methyl quinazolin-4(3H)-
ones
and their effect on GLUT4 translocation
作者:
K. Kumar G. Ramakrishna
a
;
Ravi Kumar Thakur
a
;
Venkata Reddy Pasam
a
;
Jyotsana Pandey
b
;
Rohit Mahar
c
;
Sanjeev K. Shukla
c
;
d
;
Akhilesh K. Tamrakar
b
;
d
;
Rama Pati Tripathi
a
;
d
;
rp_tripathi@cdri.res.in
;
rpt.cdri@gmail.com
关键词:
Copper(II) triflate
;
2
;
3-Dihydroquinazolin-4(1H)-
ones
;
Glycosyl quinazolin-4(3H)-
ones
;
GLUT4 translocation activity
刊名:Tetrahedron
出版年:2017
2.
Novel synthesis of tetrahydro-1H-pyrrolo[1,2-a]imidazol-2-
ones
via decarboxylative cyclization reaction of α-amino acids and α-ketoamides
作者:
Jia-shou Wu
;
jsw79@tzc.edu.cn
;
Hua-jiang Jiang
;
Jian-guo Yang
;
Zheng-neng Jin
;
Ding-ben Chen
关键词:
α-Ketoamide
;
α-Amino acid
;
Azomethine ylide
;
Decarboxylative cyclization
;
Tetrahydro-1H-pyrrolo[1
;
2-a]imidazol-2-
ones
刊名:Tetrahedron Letters
出版年:2017
3.
A structure-guided optimization of pyrido[2,3-d]pyrimidin-7-
ones
as selective inhibitors of EGFR
L858R/T790M
mutant with improved pharmacokinetic properties
作者:
Lei Yu
a
;
b
;
Minhao Huang
a
;
b
;
Tianfeng Xu
a
;
b
;
Linjiang Tong
d
;
Xiao-e Yan
e
;
Zhang Zhang
a
;
Yong Xu
a
;
Caihong Yun
e
;
Hua Xie
d
;
hxie@simm.ac.cn
;
Ke Ding
a
;
c
;
ding_ke@gibh.ac.cn
;
Xiaoyun Lu
c
;
luxy2016@jnu.edu.cn
关键词:
EGFRT790M mutant
;
Pyrido[2
;
3-d]pyrimidin-7-
ones
;
Pharmacokinetic property
;
NSCLC
;
Irreversible inhibitor
刊名:European Journal of Medicinal Chemistry
出版年:2017
4.
Synthesis of 2,3-dihydroquinazolin-4(1H)-
ones
catalyzed by α-chymotrypsin
作者:
Shi-Guo Zhang
b
;
Zong-Bo Xie
a
;
b
;
zbxie@ecit.cn
;
Lian-Sheng Liu
b
;
Meng Liang
b
;
Zhang-Gao Le
a
;
b
;
zhgle@ecit.cn
关键词:2 ;
3-Dihydroquinazolin-4(1H)-
ones
;
α-Chymotrypsin
;
Cyclocondensation
;
Biocatalysis
;
2-Aminobenzamides
刊名:Chinese Chemical Letters
出版年:2017
5.
Novel trifluoromethylated 9-amino-3,4-dihydroacridin-1(2H)-
ones
act as covalent poisons of human topoisomerase IIα
作者:
Lorena Infante Lara
a
;
Alexis Sledge
d
;
Amine Laradji
d
;
Cosmas O. Okoro
d
;
cokoro@tnstate.edu
;
Neil Osheroff
a
;
b
;
c
;
neil.osheroff@vanderbilt.edu
关键词:
Acridin-1(2H)-
ones
;
DNA topoisomerase IIα
;
Anticancer drugs
;
Covalent poison
;
DNA cleavage
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
6.
Microwave assisted synthesis of 2,3-dihydro-4H-benzo[4,5]thiazolo[3,2-a]furo[2,3-d]pyrimidin-4-
ones
and 6,7-dihydro-5H-furo[2,3-d]thiazolo[3,2-a]pyrimidin-5-
ones
using Mn(OAc)
3
作者:
Aslı Ustalar
;
Mehmet Yilmaz
;
mehmet.yilmaz@kocaeli.edu.tr
关键词:
Manganese(III) acetate
;
Radical addition
;
Cyclization
;
Microwave
;
Single crystal X-ray analysis
;
AchE inhibition
刊名:Tetrahedron Letters
出版年:2017
7.
Design, synthesis and structure-activity relationship of 4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-
ones
as potent p53-MDM2 inhibitors
作者:
Wei-Huang Zhou
a
;
b
;
Xi-Guo Xu
a
;
b
;
Jin Li
b
;
Xiao Min
b
;
Jian-Zhong Yao
b
;
Guo-Qiang Dong
b
;
Chun-Lin Zhuang
b
;
zclnathan@163.com
;
Zhen-Yuan Miao
b
;
miaozhenyuan@hotmail.com
;
Wan-Nian Zhang
a
;
b
;
zhangwnk@hotmail.com
关键词:
p53-MDM2
;
Protein&ndash
;
protein interaction
;
Inhibitors
;
Drug design
;
Structure&ndash
;
activity relationships
;
Antiproliferative
刊名:Chinese Chemical Letters
出版年:2017
8.
Immature mulberry fruits richness of promising constituents in contrast with mature
ones
: A comparative study among three Tunisian species
作者:
Aicha Jelled
a
;
b
;
jelledaicha@gmail.com
;
hassen.bencheikh@fmm.rnu.tn
;
Rihab Ben Hassine
b
;
Amira Thouri
b
;
Guido Flamini
c
;
d
;
Hassiba Chahdoura
b
;
Amira El Arem
b
;
Jihen Ben Lamine
b
;
Adnen kacem
b
;
Zohra Haouas
a
;
Hassen Ben Cheikh
a
;
Lotfi Achour
b
关键词:
Mulberry
;
Fatty acids
;
Volatiles
;
Minerals
;
Antioxidant potential
;
Maturity stages
刊名:Industrial Crops and Products
出版年:2017
9.
Discovery of 6,7-dihydro-3H-pyrano[4,3-c]isoxazol-3-
ones
as a new class of pathogen specific anti-leptospiral agents
作者:
Andivelu Ilangovan
a
;
ilangovanbdu@yahoo.com
;
Palaniappan Sakthivel
a
;
Karikalacholan Sivasankari
b
;
Charles Solomon Akino Mercy
b
;
Kalimuthusamy Natarajaseenivasan
b
关键词:
5-Carboalkoxy-2
;
3-dihydropyranone
;
6
;
7-Dihydro-3H-pyrano[4
;
3-c]isoxazol-3-one
;
Anti-leptospiral
;
Pathogen-specific
;
LipL32
刊名:European Journal of Medicinal Chemistry
出版年:2017
10.
1-Heteroarylpropan-2-
ones
as inhibitors of fatty acid amide hydrolase: Studies on structure-activity relationships and metabolic stability
作者:
Stefan Zahov
;
David Garzinsky
;
Walburga Hanekamp
;
Matthias Lehr
;
lehrm@uni-muenster.de
关键词:
Propan-2-one
;
Fatty acid amide hydrolase
;
Enzyme inhibition
;
Metabolic stability
;
Aqueous solubility
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
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