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在“Elsevier电子期刊”中，命中：809条，耗时：小于0.01 秒

1.Worsening of memory deficit induced by energy-dense diet in a rat model of early-Alzheimer's disease is associated to neurotoxic Aβ species and independent of neuroinflammation

作者：Pamela V. Martino Adami^a ; Pablo Galeano^a ; ^b ; Marina L. Wallinger^c ; Celia Quijano^d ; Alejandro Rabossi^e ; Eleonora S. Pagano^c ; Natividad Olivar^f ; Carlos Reyes Toso^c ; Daniel Cardinali^c ; Luis I. Brusco^f ; Sonia Do Carmo^g ; Rafael Radi^d ; Goar Gevorkian^h ; Eduardo M. Castañ ; o^a ; A. Claudio Cuello^g ; Laura Morelli^a ; ^{lmorelli@leloir.org.ar}

关键词：3-TyrNO2 ; 3-nitrotyrosine ; AβN3(pE) ; pyroglutamate-Aβ ; iAβ ; intraneuronal Aβ ; BBB ; blood-brain barrier ; BHI ; Bioenergetic Health Index ; CRTC ; CREB-regulated transcription coactivator ; IDE ; insulin degrading enzyme ; IR ; insulin resistance ; MetS ; metabolic syndrome ; OCR ; oxygen consumption rate ; PGC-1α ; PPARɣ coactivator 1α ; SD ; standard diet ; Sirt1 ; Sirtuin 1 ; SO ; stratum oriens ; SOD ; superoxide dismutase ; SP ; stratum pyramidale ; SRC ; spare respiratory capacity ; T2DM ; type 2 diabetes mellitus ; WA

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

2.IGF-1 protects against Aβ_25-35-induced neuronal cell death via inhibition of PUMA expression and Bax activation

作者：Xunyao Hou^a ; ^b ; ^c ; Yan Jin^d ; Jian Chen^a ; ^b ; ^c ; Yan Hong^a ; ^b ; ^c ; Dingzhen Luo^a ; ^b ; ^c ; Qingqing Yin^a ; ^b ; ^c ; Xueping Liu^a ; ^b ; ^c ; ^{xuepingliu2002@sina.com}

关键词：Aβ ; IGF-1 ; Akt ; PUMA ; Bax ; AD

刊名：Neuroscience Letters

出版年：2017

3.ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion

作者：Yu-Wen Alvin Huang¹ ; Bo Zhou¹ ; ² ; Marius Wernig² ; Thomas C. Sü ; dhof¹ ; ³ ; ^{tcs1@stanford.edu}

关键词：apolipoprotein E ; ApoE ; Alzheimer&rsquo ; s disease ; MAP kinase signaling ; amyloid precursor protein ; APP ; beta amyloid ; Aβ ; cFos ; CRISPR ; CRISPRi ; dual leucine-zipper kinase ; DLK ; transcription

刊名：Cell

出版年：2017

4.Insights into the aggregation mechanism of Aβ(25-40)

作者：Jian Xiong ; Renee D. JiJi ; ^{jijir@missouri.edu}

关键词：AD ; Alzheimer's disease ; Aβ ; β-amyloid ; ThT ; thioflavin T

刊名：Biophysical Chemistry

出版年：2017

5.Risperidone ameliorated Aβ_1-42-induced cognitive and hippocampal synaptic impairments in mice

作者：Lingzhi Wu ; Xiaowen Feng ; Tingting Li ; Baojuan Sun ; Muhammad Zahid Khan ; Ling He ; ^{heling92@hotmail.com} ; ^{hexyz@163.com}

关键词：Alzheimer&rsquo ; s disease ; Risperidone ; Cognitive impairment ; Aβ1-42

刊名：Behavioural Brain Research

出版年：2017

6.Differences in Aβ brain networks in Alzheimer's disease and healthy controls

作者：Huoqiang Duan^a ; Jiehui Jiang^a ; ^{jiangjiehui@shu.edu.cn} ; Jun Xu^a ; Hucheng Zhou^a ; Zhemin Huang^b ; ^{skywalkerhang@hotmail.com} ; Zhihua Yu^c ; ^{yzh1109@hotmail.com} ; Zhuangzhi Yan^a ; The Alzheimer's Disease Neuroimaging Initiative

关键词：Alzheimer's disease ; β-amyloid (Aβ)-cascade ; 11C-PiB PET ; Brain networks ; Graph theoretical

刊名：Brain Research

出版年：2017

7.Cross-sectional and longitudinal associations of motor fluctuations and non-motor predominance with cerebrospinal τ and Aβ as well as dementia-risk in Parkinson's disease

作者：Raluca Modreanu^a ; ^b ; Sonia Catalina Cerquera^a ; ^c ; Marí ; a José ; Martí ; ^a ; José ; Rí ; os^d ; Almudena Sá ; nchez-Gó ; mez^a ; Ana Cá ; mara^a ; Manel Ferná ; ndez^a ; Yaroslau Compta^a ; ^{ycompta@clinic.cat}

关键词：Parkinson's disease-dementia ; CSF Aβ ; CSF τ ; Endophenotypes ; Non-motor symptoms ; Motor fluctuations

刊名：Journal of the Neurological Sciences

出版年：2017

8.Dual inhibition of BACE1 and Aβ aggregation by β-ecdysone: Application of a phytoecdysteroid scaffold in Alzheimer’s disease therapeutics

作者：Sandipan Chakraborty¹ ; ^{sandipanchakraborty.13@gmail.com} ; Soumalee Basu ; ^{soumalee@gmail.com}

关键词：AD therapeutics ; BACE1 ; Aβ aggregation ; Steady-state and time-resolved fluorescence ; Molecular modeling ; AFM

刊名：International Journal of Biological Macromolecules

出版年：2017

9.Formononetin attenuates Aβ_25-35-induced cytotoxicity in HT22 cells via PI3K/Akt signaling and non-amyloidogenic cleavage of APP

作者：Lizhi Chen ; Shanshan Ou ; Lingqi Zhou ; Hai Tang ; Jie Xu ; ^{xujie@mail.sysu.edu.cn} ; Kaihua Guo ; ^{guokh@mail.sysu.edu.cn}

关键词：amyloid β ; Aβ ; Alzheimer&rsquo ; s disease ; AD ; estrogen receptor α ; ERα ; formononetin ; Form ; soluble amyloid precursor protein α ; sAPPα

刊名：Neuroscience Letters

出版年：2017

10.Aβ vaccination in combination with behavioral enrichment in aged beagles: effects on cognition, Aβ, and microhemorrhages

关键词：Aging ; Alzheimer's disease ; Brain ; Brain-derived neurotrophic factor ; Dog ; Canine ; Cerebrovascular ; Immunotherapy

刊名：Neurobiology of Aging

出版年：2017

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