设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
地图图件(2)
院士团队服务(1)
廉政文化(6)
廉政文化副本(1)
在“
Elsevier电子期刊
”中,
命中:
42,769
条,耗时:小于0.01 秒
在所有数据库中总计命中:
10
条
1.
Overexpression and enhanced specific activity of aldoketo reductases (
AK
R1B1 & AKR1B10) in human breast cancers
作者:
K. Ashok Reddy
a
;
geereddy@yahoo.com
;
P. Uday Kumar
a
;
M. Srinivasulu
b
;
B. Triveni
b
;
K. Sharada
a
;
Ayesha Ismail
a
;
G. Bhanupr
ak
ash Reddy
a
;
bhanu@icmr.org.in
关键词:
Aldose reductase
;
AK
R1B1
;
AK
R1B10
;
Breast cancer
;
Chemoresistance
;
Tumor grade
刊名:The Breast
出版年:2017
2.
Studies of T
AK
1-centered polypharmacology with novel covalent TAK1 inhibitors
作者:
Li Tan
a
;
b
;
j
;
Deep
ak
Gurbani
c
;
j
;
Ellen L. Weisberg
e
;
f
;
j
;
Douglas S. Jones
g
;
h
;
j
;
Suman Rao
a
;
b
;
g
;
William D. Singer
c
;
d
;
Faviola M. Bernard
c
;
d
;
Samar Mowafy
a
;
b
;
i
;
Annie Jenney
g
;
Guangyan Du
a
;
b
;
Atsushi Nonami
e
;
f
;
James D. Griffin
e
;
f
;
Douglas A. Lauffenburger
h
;
Kenneth D. Westover
c
;
d
;
Kenneth.Westover@UTSouthwestern.edu
;
Peter K. Sorger
g
;
Peter_Sorger@hms.harvard.edu
;
Nathanael S. Gray
a
;
b
;
Nathanael_Gray@dfci.harvard.edu
关键词:
T
AK
1
;
Polypharmacology
;
Multitarget
;
Cancer
;
Cytokine secretion
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
3.
Target regulation of PI3K/
Ak
t/mTOR pathway by cannabidiol in treatment of experimental multiple sclerosis
作者:
Sabrina Giacoppo
a
;
Federica Pollastro
b
;
Gianpaolo Grassi
c
;
Placido Bramanti
a
;
Emanuela Mazzon
a
;
emazzon.irccs@gmail.com
关键词:
Cannabidiol
;
Multiple sclerosis
;
PI3K/
Ak
t/mTOR pathway
;
BDNF
;
Inflammation
;
Neuronal survival
刊名:Fitoterapia
出版年:2017
4.
Structure-guided development of covalent T
AK
1 inhibitors
作者:
Li Tan
a
;
b
;
j
;
Deep
ak
Gurbani
c
;
d
;
j
;
Ellen L. Weisberg
e
;
f
;
John C. Hunter
c
;
d
;
Lianbo Li
c
;
d
;
Douglas S. Jones
g
;
h
;
Scott B. Ficarro
a
;
b
;
Samar Mowafy
a
;
b
;
i
;
Chun-Pong Tam
a
;
b
;
Suman Rao
a
;
b
;
g
;
Guangyan Du
a
;
b
;
James D. Griffin
e
;
f
;
Peter K. Sorger
g
;
Jarrod A. Marto
a
;
b
;
Kenneth D. Westover
c
;
d
;
Kenneth.Westover@UTSouthwestern.edu
;
Nathanael S. Gray
a
;
b
;
Nathanael_Gray@dfci.harvard.edu
关键词:
Structure-based design
;
T
AK
1 kinase inhibitors
;
Covalent inhibitors
;
2
;
4-Disubstituted pyrimidine
;
Structure-activity relationship
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
5.
Loss of TRADD attenuates pressure overload-induced cardiac hypertrophy through regulating T
AK
1/P38 MAPK signalling in mice
作者:
Lianpin Wu
a
;
b
;
1
;
Zhiyong Cao
c
;
1
;
Ling Ji
d
;
Liqin Mei
e
;
Qike Jin
b
;
Jingjing Zeng
b
;
Jiafeng Lin
b
;
Maoping Chu
b
;
Lei Li
b
;
lileiii@yahoo.com
;
Xiangjun Yang
a
;
th.reestonee@gmail.com
关键词:
T
AK
1
;
Pressure overload
;
TRADD
;
Cardiac hypertrophy
刊名:Biochemical and Biophysical Research Communications
出版年:2017
6.
J
ak
1/Stat3 signaling acts as a positive regulator of pluripotency in chicken pre-gastrula embryos
作者:
Shota N
ak
anoh
a
;
1
;
n
ak
anoh@nibb.ac.jp
;
Naoyuki Fuse
a
;
b
;
2
;
Ryosuke Tadokoro
c
;
Yoshiko T
ak
ahashi
c
;
d
;
Kiyokazu Agata
a
;
3
;
kiyokazu.agata@g
ak
ushuin.ac.jp
关键词:
Pluripotent state
;
IL6/J
ak
1/Stat3
;
Nanog
;
Blastoderm
刊名:Developmental Biology
出版年:2017
7.
The intellectual disability protein P
AK
3 regulates oligodendrocyte precursor cell differentiation
作者:
Majistor Raj Luxman Maglorius Renkilaraj
a
;
1
;
Lucas Baudouin
b
;
1
;
Claire M. Wells
c
;
Mohamed Doulazmi
d
;
Rosine Wehrlé
;
a
;
Vidjeacoumary Cannaya
a
;
Corinne Bachelin
b
;
Jean-Vianney Barnier
e
;
Zhengping Jia
f
;
Brahim Nait Oumesmar
b
;
Isabelle Dusart
a
;
Lamia Bouslama-Oueghlani
a
;
b
;
lamia.bouslama@upmc.fr
关键词:
P
AK
3
;
Differentiation
;
Oligodendrocyte
;
OPC
;
Intellectual disability
;
Myelin
;
Development
刊名:Neurobiology of Disease
出版年:2017
8.
Structural pliability adjacent to the kinase domain highlights contribution of F
AK
1 IDRs to cytoskeletal remodeling
作者:
Jaymin J. Kathiriya
a
;
Ravi Ramesh Path
ak
a
;
Alexandr Bezginov
c
;
Bin Xue
d
;
Vladimir N. Uversky
e
;
f
;
g
;
Elisabeth R.M. Tillier
c
;
Vrushank Davé
;
a
;
b
;
vdave@health.usf.edu
关键词:
Intrinsic disorder in kinases
;
Evolution of kinases
;
F
AK
1 signaling
;
Hub proteins
;
Protein-protein interaction networks
;
Network medicine
刊名:Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
出版年:2017
9.
Heightened aggressive behavior in mice deficient in aldo-keto reductase 1a (
Ak
r1a)
作者:
T
ak
ujiro Homma
a
;
Ryusuke
Ak
ihara
a
;
Satoshi Okano
b
;
Mototada Shichiri
c
;
Yasukazu Yoshida
d
;
Ken-ichi Yamada
e
;
f
;
Satoshi Miyata
g
;
Osamu N
ak
ajima
b
;
Junichi Fujii
a
;
jfujii@med.id.yamagata-u.ac.jp
;
sodprdx@gmail.com
关键词:
Ak
r1a
;
Ascorbic acid
;
Intermale aggression
;
Stress
刊名:Behavioural Brain Research
出版年:2017
10.
Quercetin attenuates high fructose feeding-induced atherosclerosis by suppressing inflammation and apoptosis via ROS-regulated PI3K/
AK
T signaling pathway
作者:
Xue-Li Lu
;
1
;
luxli123@126.com
;
Cui-Hua Zhao
1
;
Xin-Liang Yao
;
Han Zhang
关键词:
Quercetin
;
High fructose
;
Atherosclerosis
;
ROS
;
PI3K/
AK
T
刊名:Biomedicine & Pharmacotherapy
出版年:2017
1
2
3
4
5
6
7
8
9
查看站内搜索结果(19)
按检索点细分(42769)
题名(3608)
作者(26655)
关键词(2864)
文摘(13585)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.