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在“Elsevier电子期刊”中，命中：3,497条，耗时：0.0469811 秒

在所有数据库中总计命中：15,421条

1.Transcriptome profiling of NIH3T3 cell lines expressing opsin and the P23H opsin mutant identifies candidate drugs for the treatment of retinitis pigmentosa

作者：Yuanyuan Chen^a ; Matthew J. Brooks^b ; Linn Gieser^b ; Anand Swaroop^b ; Krzysztof Palczewski^a ; ^{kxp65@case.edu}

关键词：ad ; autosomal dominant ; BP ; biological process ; CHOP ; C/EBP homologous protein ; CRE ; the cAMP-responsive element ; CREB ; the cAMP-responsive element-binding protein ; CREM ; the cAMP-responsive element modulator ; ATF-1 ; activating transcription factor-1 ; DAVID ; the database for annotation visualization and integrated discovery ; DE ; differential expression ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; ER ; endoplasmic reticulum ; ERAD ; ER-associated protein degradation ; FDA ; Food and Drug Adm

刊名：Pharmacological Research

出版年：2017

2.Development of potential candidate reference materials for drugs in bottom sediment, cod and herring tissues

作者：Irena Baranowska^a ; ^{irena.baranowska@polsl.pl} ; Bogusław Buszewski^b ; Jacek Namieśnik^c ; Piotr Konieczka^c ; Sylwia Magiera^a ; Halina Polkowska-Motrenko^d ; Paweł Kościelniak^e ; Renata Gadzała-Kopciuch^b ; Aneta Woźniakiewicz^e ; Zbigniew Samczyński^d ; Kinga Kochańska^c ; Małgorzata Rutkowska^c

关键词：Potential reference material ; Drug ; Bottom sediment ; Fish tissues

刊名：Chemosphere

出版年：2017

3.Microbial biosensors to monitor the encapsulation effectiveness of Doxorubicin in chimeric advanced Drug Delivery Nano Systems: A calorimetric approach

作者：Konstantinos Gardikis^b ; Marco Signorelli^a ; Chiara Ferrario^a ; Alberto Schiraldi^a ; Maria Grazia Fortina^a ; Sophia Hatziantoniou^b ; Costas Demetzos^b ; Dimitrios Fessas^a ; ^{dimitrios.fessas@unimi.it}

关键词：chi-aDDnS ; chimeric advanced Drug Delivery nano-Systems ; ITC ; Isothermal Titration Calorimetry ; DOX ; doxorubicin ; Lactobacillus helveticus ; L. helveticus

刊名：International Journal of Pharmaceutics

出版年：2017

4.In vitro monitoring of amyloid β-peptide oligomerization by Electrospray differential mobility analysis: An alternative tool to evaluate Alzheimer's disease drug candidates

作者：Dimitri Brinet^a ; ^b ; Franç ; ois Gaie-Levrel^c ; Vincent Delatour^c ; Julia Kaffy^a ; Sandrine Ongeri^a ; Myriam Taverna^b ; ^{myriam.taverna@u-psud.fr}

关键词：Aβ ; Amyloid-beta peptide ; AD ; Alzheimer's disease ; CE ; Capillary Electrophoresis ; ThT ; Thioflavin-T ; TEM ; Transmission Electron Microscopy ; DC ; drug candidate ; SEC ; Size Exclusion Chromatography ; FCS ; fluorescence correlation spectroscopy ; FFF ; field flow fractionation ; ES-DMA ; Electrospray differential mobility analysis ; DMAS or SMPS ; Differential Mobility Analyzing System ; WCPC ; Water Condensation Particle Counter

刊名：Talanta

出版年：2017

5.Construction and characterization of a pure protein hydrogel for drug delivery application

作者：Xu Xu^a ; ^b ; ZhaoKang Xu^b ; XiaoFeng Yang^a ; YanHao He^a ; Rong Lin^a ; ^{linrong@mail.xjtu.edu.cn}

关键词：Hydrogel ; Recombinant proteins ; Drug delivery ; In vitro release

刊名：International Journal of Biological Macromolecules

出版年：2017

6.Developing an in silico pipeline for faster drug candidate discovery: Virtual high throughput screening with the Signature molecular descriptor using support vector machine models

作者：Jonathan Jun Feng Chen^a ; Donald Patrick Visco Jr.^b

关键词：Virtual high throughput screening ; QSAR ; Drug discovery ; CAMD ; Signature

刊名：Chemical Engineering Science

出版年：2017

7.The drug candidate, ADX71441, is a novel, potent and selective positive allosteric modulator of the GABA_B receptor with a potential for treatment of anxiety, pain and spasticity

作者：Mikhail Kalinichev ; ^{mikhail.kalinichev@ipsen.com} ; Franç ; oise Girard ; Hasnaà ; Haddouk ; Mé ; lanie Rouillier ; Eric Riguet ; Isabelle Royer-Urios ; Vincent Mutel ; Robert Lü ; tjens ; Sonia Poli

关键词：Allosteric modulator ; GABA ; Anxiety ; Pain ; Body temperature ; Baclofen ; Spasticity ; Clinical candidate

刊名：Neuropharmacology

出版年：2017

8.Biomimetic synthesis of sericin and silica hybrid colloidosomes for stimuli-responsive anti-cancer drug delivery systems

作者：Ying Yang^a ; Yurong Cai^a ; ^{caiyr@zstu.edu.cn} ; Ning Sun^a ; Ruijing Li^a ; Wenhua Li^a ; Subhas C. Kundu^b ; ^c ; Xiangdong Kong^d ; Juming Yao^a ; ^{yaoj@zstu.edu.cn}

关键词：Sericin ; Synthesis ; Colloidosomes ; Stimuli-responsive ; Drug delivery

刊名：Colloids and Surfaces B: Biointerfaces

出版年：2017

9.Using X-Ray Crystallography to Simplify and Accelerate Biologics Drug Development

作者：Mark L. Brader¹ ; ^{mbra988@aucklanduni.ac.nz} ; Edward N. Baker¹ ; Michael F. Dunn² ; Thomas M. Laue³ ; John F. Carpenter⁴

关键词：biopharmaceuticals characterization ; biotechnology ; crystal structure ; crystallization ; crystallography ; crystals ; protein formulation ; protein structure

刊名：Journal of Pharmaceutical Sciences

出版年：2017

10.Single chain Fc-dimer-human growth hormone fusion protein for improved drug delivery

作者：Li Zhou^a ; Hsuan-Yao Wang^a ; Shanshan Tong^a ; ^b ; Curtis T. Okamoto^a ; Wei-Chiang Shen^a ; ^{weishen@usc.edu} ; Jennica L. Zaro^a ; ^c ; ^{jZaro@westcoastuniversity.edu}

关键词：Fc fusion ; Single chain Fc ; Protein delivery ; Human growth hormone ; Pharmacokinetics ; Pharmacodynamics

刊名：Biomaterials

出版年：2017

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