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在“Elsevier电子期刊”中，命中：1,969条，耗时：0.0929478 秒

在所有数据库中总计命中：26,417条

1.Synthesis and in vitro antitumor activity of novel naphthyridinone derivatives

作者：Xue-Dong Jia^a ; ^b ; Shuo Wang^a ; Ming-Hua Wang^a ; Ming-Liang Liu^a ; ^{lmllyx@126.com} ; Gui-Min Xia^a ; Xiu-Jun Liu^a ; Yun Chai^a ; Hong-Wei He^a ; ^{hehwei@imb.pumc.edu.cn}

关键词：Naphthyridinones ; Synthesis ; Antitumor activity ; Voreloxin

刊名：Chinese Chemical Letters

出版年：2017

2.Enhanced in vitro cytotoxicity and anti-tumor activity of vorinostat-loaded pluronic micelles with prolonged release and reduced hepatic and renal toxicities

作者：Elham Abdelmonem Mohamed^a ; ^{elhamelsaid@yahoo.com} ; Irhan Ibrahim Abu Hashim^a ; Rehab Mohammad Yusif^a ; ^d ; Ghada Mohamed Suddek^b ; Ahmed Abdel Aziz Shaaban^b ; Farid Abd Elreheem Badria^c

关键词：Vorinostat ; Polymeric micelles ; Pluronic ; In vitro cytotoxicity ; Antitumor activity

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

3.Synthesis and antitumor activity of some new pyrazolo[1,5-a]pyrimidines

作者：Ashraf S. Hassan^a ; ^{ashraf_salmoon@yahoo.com} ; Mohamed F. Mady^b ; ^c ; Hanem M. Awad^d ; Taghrid S. Hafez^a

关键词：5-Amino-1H-pyrazole ; Pyrazolo[1 ; 5-a]pyrimidine ; Schiff bases ; MTT assay ; Anticancer activity ; Structure activity relationship

刊名：Chinese Chemical Letters

出版年：2017

4.3-Aroylindoles display antitumor activity in vitro and in vivo: Effects of N1-substituents on biological activity

作者：Hsueh-Yun Lee^a ; Jiann-Fong Lee^a ; Sunil Kumar^a ; Yi-Wen Wu^b ; Wei-Chun HuangFu^c ; Mei-Jung Lai^d ; Yu-Hsuan Li^a ; Hsiang-Ling Huang^a ; Fei-Chiao Kuo^a ; Che-Jen Hsiao^e ; Chun-Chun Cheng^c ; Chia-Ron Yang^b ; ^{cryang@ntu.edu.tw} ; Jing-Ping Liou^a ; ^{jpl@tmu.edu.tw}

关键词：Anticancer agents ; Histone deacetylase inhibitors ; 3-Aroylindoles ; Tubulin polymerization inhibition

刊名：European Journal of Medicinal Chemistry

出版年：2017

5.Structure-based design and synthesis of imidazo[1,2-a]pyridine derivatives as novel and potent Nek2 inhibitors with in vitro and in vivo antitumor activities

作者：Jian-Bei Xi^a ; ¹ ; Yan-Fen Fang^a ; ¹ ; Brendan Frett^b ; ¹ ; Meng-Li Zhu^a ; Tong Zhu^a ; Yan-Nan Kong^a ; Feng-Jie Guan^a ; Yun Zhao^a ; Xiong-Wen Zhang^a ; ^{xwzhang@sat.ecnu.edu.cn} ; Hong-yu Li^b ; ^HLi2@uams.ed ; Ming-Liang Ma^a ; ^{mlma@brain.ecnu.edu.cn} ; Wenhao Hu^a ; ^{whu@chem.ecnu.edu.cn}

关键词：Nek2 inhibitors ; Imidazo[1 ; 2-a]pyridine ; Antitumor activity ; Selectivity

刊名：European Journal of Medicinal Chemistry

出版年：2017

6.Synthesis and characterization of a new alkyne functionalized bis(pyrazolyl)methane ligand and of its Pd(II) complexes: Evaluation of their in vitro cytotoxic activity

作者：Corrado Di Nicola^a ; Fabio Marchetti^b ; ^{fabio.marchetti@unicam.it} ; Claudio Pettinari^a ; Riccardo Pettinari^a ; Fabrizia Brisdelli^c ; Marcello Crucianelli^d ; ^{marcello.crucianelli@univaq.it} ; Camilla Lelii^d ; Alessandra Crispini^e

关键词：Bis(pyrazolyl)alkanes ; Palladium(II) complexes ; X-ray structure ; Antitumor activity

刊名：Inorganica Chimica Acta

出版年：2017

7.Copper (II) complexes possessing alkyl-substituted polypyridyl ligands: Structural characterization and in vitro antitumor activity

作者：Noah R. Angel^a ; ¹ ; Raneen M. Khatib^a ; ¹ ; Julia Jenkins^a ; Michelle Smith^a ; Justin M. Rubalcava^a ; Brian Khoa Le^a ; Daniel Lussier^a ; Zhuo (Georgia) Chen^b ; Fook S. Tham^a ; Emma H. Wilson^c ; Jack F. Eichler^a ; ^{jack.eichler@ucr.edu}

关键词：Copper(II) ; Polypyridyl ; Phenanthroline ; Bipyrydine ; Synthesis ; Anticancer

刊名：Journal of Inorganic Biochemistry

出版年：2017

8.Glycosylation and antiproliferative activity of hyperglycosylated IFN-α2 potentiate HEK293 cells as biofactories

作者：Agustina Gugliotta^a ; Natalia Ceaglio^a ; Brenda Raud^b ; Guillermina Forno^b ; ^c ; Laura Mauro^c ; Ricardo Kratje^a ; Marcos Oggero^a ; ^{moggero@fbcb.unl.edu.ar}

关键词：Hyperglycosylated IFN-α2b ; N-glycosylation ; Glycoproteins ; Antitumoral activity ; Pharmacokinetics ; HEK293 cells ; CHO cells

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2017

9.In Vitro and In Vivo Activity of Lucitanib in FGFR1/2 Amplified or Mutated Cancer Models

作者：Federica Guffanti^* ; ³ ; Rosaria Chilà ; ^* ; ³ ; Ezia Bello^* ; Massimo Zucchetti^&dagger ; ; Monique Zangarini^&dagger ; ; Laura Ceriani^&dagger ; ; Mariella Ferrari^&dagger ; ; Monica Lupi^&dagger ; ; Anne Jacquet-Bescond^&Dagger ; ; Mike F. Burbridge^&Dagger ; ; Marie-Jeanne Pierrat^&Dagger ; ; Giovanna Damia^* ; ^{giovanna.damia@marionegri.it}

刊名：Neoplasia

出版年：2017

10.Lx2-32c, a novel semi-synthetic taxane, exerts antitumor activity against prostate cancer cells in vitro and in vivo

作者：Guangyao Lv^a ; ^&dagger ; ; Dengjun Sun^b ; ^&dagger ; ; Jingwen Zhang^a ; Xiaoxia Xie^a ; Xiaoqiong Wu^d ; Weishuo Fang^c ; Jingwei Tian^a ; Chunhong Yan^e ; Hongbo Wang^a ; ^{hongbowangyt@gmail.com} ; Fenghua Fu^a ; ^{fufenghua@sohu.com}

关键词：Lx2-32c ; Cephalomannine ; Prostate cancer ; Microtubule ; Cell cycle arrest ; Apoptosis

刊名：Acta Pharmaceutica Sinica B

出版年：2017

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