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内部出版物
在“
Elsevier电子期刊
”中,
命中:
1,009
条,耗时:小于0.01 秒
1.
Sampling only ten microliters of whole blood for the quantification of poorly soluble drugs:
Itraconazole
as case study
作者:
Justine Thiry
a
;
Brigitte Evrard
a
;
Gwenaë
;
l Nys
b
;
Marianne Fillet
b
;
Miranda G.M. Kok
b
;
miranda.kok@ulg.ac.be
关键词:
ACN
;
acetonitrile
;
BCS
;
biopharmaceutics classification system
;
DBS
;
dried blood spot
;
FA
;
formic acid
;
FDA
;
food and drug administration
;
HPLC
;
high performance liquid chromatography
;
IPA
;
isopropanol
;
ITZ
;
itraconazole
;
MeOH
;
methanol
;
MRM
;
multiple reaction monitoring
;
MS
;
mass spectrometry
;
OH-ITZ
;
hydroxy-
itraconazole
;
TFA
;
trifluoroacetic acid
;
UHPLC
;
ultra-high performance liquid chromatography
;
UV
;
ultraviolet
;
VAMS
;
volumetric absorptive microsampling
刊名:Journal of Chromatography A
出版年:2017
2.
Anti-proliferation of breast cancer cells with
itraconazole
: Hedgehog pathway inhibition induces apoptosis and autophagic cell death
作者:
Xiaoya Wang
a
;
b
;
1
;
543596983@qq.com
;
Sanhua Wei
c
;
1
;
Sanhuawei3@163.com
;
Yong Zhao
a
;
1
;
zhaoyong8@aliyun.com
;
Changhong Shi
a
;
changhong@fmmu.edu.cn
;
Peijuan Liu
a
;
liupeij1989077@126.com
;
Caiqin Zhang
a
;
zhangcaiqin-beibei@163.com
;
Yingfeng Lei
d
;
yflei@fmmu.edu.cn
;
Bo Zhang
e
;
zhangbo@fmmu.edu.cn
;
Bing Bai
a
;
bone_1999@163.com
;
Yong Huang
b
;
Yonghuang@nwsuaf.edu.cn
;
Hai Zhang
a
;
hzhang@fmmu.edu.cn
关键词:
Breast cancer
;
Itraconazole
;
Apoptosis
;
Autophagic cell death
;
Hedgehog pathway
刊名:Cancer Letters
出版年:2017
3.
Improved oral absorption profile of
itraconazole
in hypochlorhydria by self-micellizing solid dispersion approach
作者:
Yoshiki Kojo
;
Saori Matsunaga
;
Hiroki Suzuki
;
Hideyuki Sato
;
Yoshiki Seto
;
Satomi Onoue
;
onoue@u-shizuoka-ken.ac.jp
关键词:
ADI
;
acceptable daily intake
;
AUC
;
area under the curve of blood concentration vs. time
;
DLS
;
dynamic light scattering
;
DMEM
;
Dulbecco's modified Eagle's medium
;
DMSO
;
dimethyl sulfoxide
;
DSC
;
differential scanning calorimetry
;
GI
;
gastrointestinal
;
IEC6 cell
;
intestinal epithelioid cell line No.6 derived from neonatal rat ileum
;
ITZ
;
itraconazole
;
LD50
;
lethal dose 50%
;
LDH
;
lactate dehydrogenase
;
NaPB
;
sodium phosphate buffer
;
PLM
;
polarized light microscopy
;
PXRD
;
powder X-ray diffraction
;
RH
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
4.
Bioavailability enhancement of
itraconazole
-based solid dispersions produced by hot melt extrusion in the framework of the Three Rs rule
作者:
Justine Thiry
a
;
jthiry@ulg.ac.be
;
Miranda G.M. Kok
b
;
Laurence Collard
a
;
Antoine Frè
;
re
a
;
Fabrice Krier
a
;
Marianne Fillet
b
;
Brigitte Evrard
a
关键词:
ACN
;
acetonitrile
;
API
;
active pharmaceutical ingredient
;
ASD
;
amorphous solid dispersions
;
AUC
;
area under the curve
;
BCS
;
biopharmaceutics classification system
;
CD
;
cyclodextrin
;
Cmax
;
maximum concentration
;
DSC
;
differential scanning calorimetry
;
FA
;
formic acid
;
FDA
;
Food and Drug Administration
;
HME
;
hot melt extrusion
;
HPLC
;
high performance liquid chromatography
;
IPA
;
isopropanol
;
ITZ
;
itraconazole
;
MeOH
;
methanol
;
MRM
;
multiple reaction monitoring
;
MS
;
mass spectrometry
;
ns
;
not signifi
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
5.
Simultaneous determination of
itraconazole
, hydroxy
itraconazole
, keto
itraconazole
and N-desalkyl
itraconazole
concentration in human plasma using liquid chromatography with tandem mass spectrometry
作者:
Xiaorong Liang
a
;
Liang.Xiaorong@gene.com" class="auth_mail" title="E-mail the corresponding author
;
Michael Van Parys
b
;
Xiao Ding
a
;
Ning Zeng
c
;
Luke Bi
c
;
Drew Dorshort
b
;
Janine McKnight
b
;
Dennis Milanowski
b
;
Jialin Mao
a
;
Yuan Chen
a
;
Joseph A Ware
d
;
Brian Dean
a
;
Cornelis E.C.A. Hop
a
;
Yuzhong Deng
a
关键词:
LC&ndash
;
MS
;
Human plasma
;
Itraconazole
;
Hydroxy
itraconazole
;
Keto
itraconazole
;
N-desalkyl
itraconazole
;
Drug-drug interaction
刊名:Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences
出版年:2016
6.
Impact of detergents on the physiochemical behavior of
itraconazole
loaded nanostructured lipid carriers
作者:
A. Bhadra
a
;
G. Karmakar
b
;
P. Nahak
b
;
P. Chettri
c
;
B. Roy
b
;
P. Guha
b
;
A.K. Mandal
d
;
R.K. Nath
e
;
A.K. Panda
f
;
akpanda@mail.vidyasagar.ac.in
;
akpanda1@yahoo.com
关键词:
NLC
;
ITZ
;
DLS
;
DSC
;
Drug release
;
Antifungul activity
刊名:Colloids and Surfaces A: Physicochemical and Engineering Aspects
出版年:2017
7.
Single jugular vein cannulated rats may not be suitable for intravenous pharmacokinetic screening of high logP compounds
作者:
Nilesh Gaud
a
;
Anoop Kumar
a
;
Muralikrishna Matta
a
;
Prashant Kole
a
;
Srikanth Sridhar
c
;
Sandhya Mandlekar
b
;
Vinay K. Holenarsipur
a
;
vinay.gupta@syngeneintl.com
关键词:
Amiodarone
;
Atenolol
;
Blood sampling methods
;
Dual cannulation
;
Itraconazole
;
Jugular vein
;
Non-specific binding
;
Rat pharmacokinetic studies
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
8.
Optimization and scaling-up of ITZ-based dry powders for inhalation
作者:
Romain Merlos
a
;
rmerlos@ulb.ac.be
;
Nathalie Wauthoz
a
;
nawautho@ulb.ac.be
;
Vincent Levet
a
;
vlevet@ulb.ac.be
;
Laure Belhassan
b
;
lbelh@smb.be
;
Thami Sebti
b
;
tsebt@smb.be
;
Francis Vanderbist
b
;
fvdbi@smb.be
;
Karim Amighi
a
;
kamighi@ulb.ac.be
关键词:
Itraconazole
;
Solid dispersion
;
Pulmonary delivery
;
Spray-drying
;
Pilot-scale production
刊名:Journal of Drug Delivery Science and Technology
出版年:2017
9.
The in vitro evaluation of ketoconazole and its alternative clinical CYP3A4/5 inhibitors (ritonavir, clarithromycin and
itraconazole
) as inhibitors of non-CYP enzymes
作者:
David B. Buckley
;
Brian W. Ogilvie
;
Phyllis Yerino
刊名:Drug Metabolism and Pharmacokinetics
出版年:2017
10.
Prevalence of Candida spp. in cervical-vaginal samples and the in vitro susceptibility of isolates
作者:
Tchana Martinez Brandolt
a
;
b
;
Gabriel Baracy Klafke
a
;
Carla Vitola Gonç
;
alves
b
;
Laura Riffel Bitencourt
a
;
Ana Maria Barral de Martinez
b
;
Josiara Furtado Mendes
c
;
Má
;
rio Carlos Araú
;
jo Meireles
c
;
Melissa Orzechowski Xavier
a
;
b
;
melissaxavierfurg@gmail.com
关键词:
Vulvovaginal candidiasis
;
Antifungal
;
Susceptibility
;
Resistance
刊名:Brazilian Journal of Microbiology
出版年:2017
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