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CNKI学位论文(187)
知网期刊论文(46)
在“
Elsevier电子期刊
”中,
命中:
57
条,耗时:0.0230224 秒
在所有数据库中总计命中:
233
条
1.
Triazolopyridin
e
e
th
e
rs as pot
e
nt, orally activ
e
mGlu
2
positiv
e
allost
e
ric modulators for tr
e
ating schizophr
e
nia
作者:
M
e
ndi A. Higgins
;
m
e
ndi.higgins@bms.com
;
Lawr
e
nc
e
R. Marcin
;
F. Christoph
e
r Zusi
;
Rob
e
rt G
e
ntl
e
s
;
Min Ding
;
Bradl
e
y C. P
e
arc
e
;
Amy
E
aston
;
Walt
e
r A. Kostich
;
Matth
e
w A. S
e
ag
e
r
;
Clotild
e
Bourin
;
Linda J. Bristow
;
Kim A.
John
son
;
R
e
gina Mill
e
r
;
John
Hogan
;
Val
e
ri
e
Whit
e
rock
;
Micha
e
l Gulian
e
llo
;
M
e
r
e
dith F
e
rrant
e
;
Yanling Huang
;
Adam H
e
ndricson
;
Andr
e
w Alt
;
John
E
.
Macor
;
Joann
e
J. Bronson
关键词:
Schizophr
e
nia
;
mGlu2
;
M
e
tabotropic glutamat
e
r
e
c
e
ptors
;
Triazolopyridin
e
刊名:Bioorganic & M
e
dicinal Ch
e
mistry
出版年:2017
2.
D
e
v
e
lopm
e
nt of spiroguanidin
e
-d
e
riv
e
d α7 n
e
uronal nicotinic r
e
c
e
ptor partial agonists
作者:
Matth
e
w D. Hill
;
matth
e
w.hill@bms.com
;
Haiquan Fang
;
Sivarao V. Digavalli
;
Francin
e
L. H
e
aly
;
Lizb
e
th Gallagh
e
r
;
D
e
bra Post-Munson
;
Ping Ch
e
n
;
Joann
e
Natal
e
;
Yulia B
e
nit
e
x
;
Dani
e
l Morgan
;
Nicholas Lodg
e
;
Linda Bristow
;
John
E
.
Macor
;
Richard
E
. Olson
关键词:
α7 nicotinic ac
e
tylcholin
e
r
e
c
e
ptor
;
Schizophr
e
nia
;
5-HT3A r
e
c
e
ptor
;
Spiroguanidin
e
;
Imm
e
diat
e
e
arly g
e
n
e
s
刊名:Bioorganic & M
e
dicinal Ch
e
mistry L
e
tt
e
rs
出版年:2017
3.
Synth
e
sis and SAR of calcitonin g
e
n
e
-r
e
lat
e
d p
e
ptid
e
(CGRP) antagonists containing substitut
e
d aryl-pip
e
razin
e
s and pip
e
ridin
e
s
作者:
Rita L. Civi
e
llo
;
Xiaojun Han
;
Br
e
tt R. B
e
no
;
Prasad V. Chaturv
e
dula
;
John
J. H
e
rbst
;
C
e
n Xu
;
Charl
e
s M. Conway
;
John
E
.
Macor
;
G
e
n
e
M. Dubowchik
关键词:
CGRP r
e
c
e
ptor antagonist
;
Calcitonin g
e
n
e
-r
e
lat
e
d p
e
ptid
e
(CGRP)
;
Migrain
e
h
e
adach
e
刊名:Bioorganic & M
e
dicinal Ch
e
mistry L
e
tt
e
rs
出版年:2016
4.
Difluorocyclobutylac
e
tyl
e
n
e
s as positiv
e
allost
e
ric modulators of mGluR5 with r
e
duc
e
d bioactivation pot
e
ntial
作者:
Andr
e
w P. D
e
gnan
;
andr
e
w.d
e
gnan@bms.com
;
Darr
e
ll Maxw
e
ll
;
Anand Balakrishnan
;
J
e
ffr
e
y M. Brown
;
Amy
E
aston
;
Micha
e
l Gulian
e
llo
;
Um
e
sh Hanum
e
gowda
;
M
e
lissa Hill-Drz
e
wi
;
R
e
gina Mill
e
r
;
K
e
nn
e
th S. Santon
e
;
Arun S
e
napati
;
E
ric E. Shi
e
lds
;
Digavalli V. Sivarao
;
Ryan W
e
stphal
;
Val
e
ri
e
J. Whit
e
rock
;
Xiaoliang Zhuo
;
Joann
e
J. Bronson
;
John
E
.
Macor
关键词:
mGluR5
;
PAMs
;
Cognition
;
Schizophr
e
nia
;
Bioactivation
刊名:Bioorganic & M
e
dicinal Ch
e
mistry L
e
tt
e
rs
出版年:2016
5.
Synth
e
sis of pyrimido[4,5-c]az
e
pin
e
- and pyrimido[4,5-c]ox
e
pin
e
-bas
e
d γ-s
e
cr
e
tas
e
modulators
作者:
Yong-Jin Wu
;
Yong-Jin.wu@bms.com" class="auth_mail" titl
e
="E-mail th
e
corr
e
sponding author
;
Yunhui Zhang
;
J
e
r
e
my H. Toyn
;
John
E
.
Macor
;
Lorin A. Thompson
关键词:
γ-S
e
cr
e
tas
e
modulator (GSM)
;
2-Chloro-pyrimido[4
;
5-c]az
e
pin-4-amin
e
;
2-Chloro-pyrimido[4
;
5-c]ox
e
pin-4-amin
e
;
Ring-closing m
e
tath
e
sis (RCM)
刊名:Bioorganic & M
e
dicinal Ch
e
mistry L
e
tt
e
rs
出版年:2016
6.
Synth
e
sis and
e
valuation of carbamat
e
and aryl
e
th
e
r substitut
e
d pyrazinon
e
s as corticotropin r
e
l
e
asing factor-1 (CRF
1
) r
e
c
e
ptor antagonists
作者:
Vijay T. Ahuja
;
vijay.ahuja@bms.com" class="auth_mail" titl
e
="E-mail th
e
corr
e
sponding author
;
Richard A. Hartz
;
Thadd
e
us F. Molski
;
Gail K. Mattson
;
Kimb
e
rl
e
y A. L
e
ntz
;
Jam
e
s E. Grac
e
Jr.
;
Nicholas J. Lodg
e
;
Joann
e
J. Bronson
;
John
E
.
Macor
关键词:
CRF1 r
e
c
e
ptor antagonists
;
CRF
;
D
e
pr
e
ssion
;
N
e
urosci
e
nc
e
;
Pyrazinon
e
s
刊名:Bioorganic & M
e
dicinal Ch
e
mistry L
e
tt
e
rs
出版年:2016
7.
D
e
sign and optimization of tricyclic gamma-s
e
cr
e
tas
e
modulators
作者:
Jianliang Shi
;
jianling.shi@bms.com" class="auth_mail" titl
e
="E-mail th
e
corr
e
sponding author
;
Dmitry Zu
e
v
;
Li Xu
;
Kimb
e
rl
e
y A. L
e
ntz
;
Jam
e
s E. Grac
e
;
J
e
r
e
my H. Toyn
;
Richard
E
. Olson
;
John
E
.
Macor
;
Lorin A. Thompson
关键词:
Alzh
e
im
e
r&rsquo
;
s dis
e
as
e
;
Gamma-s
e
cr
e
tas
e
modulators
;
CYP3A4 inhibition
刊名:Bioorganic & M
e
dicinal Ch
e
mistry L
e
tt
e
rs
出版年:2016
8.
Oxazolidinon
e
-bas
e
d allost
e
ric modulators of mGluR5: D
e
fining mol
e
cular switch
e
s to cr
e
at
e
a pharmacological tool box
作者:
Hong Huang
;
Andr
e
w P. D
e
gnan
;
Anand Balakrishnan
;
Amy
E
aston
;
Micha
e
l Gulian
e
llo
;
Yanling Huang
;
Mich
e
l
e
Match
e
tt
;
Gail Mattson
;
R
e
gina Mill
e
r
;
K
e
nn
e
th S. Santon
e
;
Arun S
e
napati
;
E
ric E. Shi
e
lds
;
Digavalli V. Sivarao
;
Lawr
e
nc
e
B. Snyd
e
r
;
Ryan W
e
stphal
;
Val
e
ri
e
J. Whit
e
rock
;
Fukang Yang
;
Joann
e
J. Bronson
;
John
E
.
Macor
关键词:
mGluR5
;
mGlu5
;
Positiv
e
allost
e
ric modulator
;
Sil
e
nt allost
e
ric modulator
;
Schizophr
e
nia
;
Cognition
刊名:Bioorganic & M
e
dicinal Ch
e
mistry L
e
tt
e
rs
出版年:2016
9.
Macrocyclic prolinyl acyl guanidin
e
s as inhibitors of β-s
e
cr
e
tas
e
(BACE)
作者:
K
e
nn
e
th M. Boy
;
boyk@bms.com" class="auth_mail" titl
e
="E-mail th
e
corr
e
sponding author
;
Jason M. Gu
e
rnon
;
Yong-Jin Wu
;
Yunhui Zhang
;
Jo
e
Shi
;
W
e
ixu Zhai
;
Shirong Zhu
;
Samu
e
l W. G
e
rritz
;
J
e
r
e
my H. Toyn
;
J
e
r
e
E. M
e
r
e
dith
;
Donna M. Bart
e
n
;
Cath
e
rin
e
R. Burton
;
Charl
e
s F. Albright
;
Andr
e
w C. Good
;
Jam
e
s E. Grac
e
;
Kimb
e
rl
e
y A. L
e
ntz
;
Richard
E
. Olson
;
John
E
.
Macor
;
Lorin A. Thompson III
关键词:
BAC
E
;
Alzh
e
im
e
r&rsquo
;
s dis
e
as
e
刊名:Bioorganic & M
e
dicinal Ch
e
mistry L
e
tt
e
rs
出版年:2015
10.
Analysis of micro-drilling of glassy c
e
ramic
Macor
nozzl
e
s for scanning dropl
e
t syst
e
ms
作者:
S.M. Afazov
a
;
Shukri.Afazov@nottingham.ac.uk
;
R. Ronaldo
a
;
D. Londsdal
e
b
;
D. Zd
e
bski
a
;
S.M. Ratch
e
v
a
关键词:
Micro-drilling
;
SPF approach
;
Mat
e
rial mod
e
lling of
Macor
;
Drilling param
e
t
e
rs
;
Dynamics of micro-drills
;
Scanning dropl
e
t syst
e
ms (SDSs)
;
Scanning dropl
e
t c
e
ll (SDC)
刊名:Journal of Mat
e
rials Proc
e
ssing T
e
chnology
出版年:2013
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