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在“Elsevier电子期刊”中，命中：198条，耗时：0.0479751 秒

在所有数据库中总计命中：256条

1.Discovery of small-molecule nonpeptide antagonists of nociceptin/orphanin FQ receptor: The studies of design, synthesis, and structure-activity relationships for (4-arylpiperidine substituted-methyl)-[bicyclic (hetero)cycloalkanobenzene] derivatives

作者：Shigeo Hayashi ; ^{Shigeo_Hayashi@nifty.com" class="auth_mail" title="E-mail the corresponding author} ; Katsuyo Ohashi ; Sachiko Mihara ; Eriko Nakata ; Chie Emoto ; Atsuko Ohta

关键词：Nociceptin/Orphanin FQ (N/OFQ) ; Human NOP (ORL1) receptor selective antagonist ; Multisite interactions with NOP receptor ; Metabolic stability ; HERG potassium ion channel binding ; Prolong QT interval issues

刊名：European Journal of Medicinal Chemistry

出版年：2016

2.Association between DNA methylation of SORL1 5′-flanking region and mild cognitive impairment in type 2 diabetes mellitus

作者：Yang Yu^a ; ^{someso@sina.com} ; Wang Mingjiao^a ; Xiaohui Yang^a ; Miao Sui^a ; Tao Zhang^a ; Jin Liang^b ; Xinyi Gu^b ; Xiaomei Wang^a

关键词：Mild cognitive impairment ; SORL1 ; Methylation ; Methylation-specific PCR

刊名：Annales d'Endocrinologie

出版年：2016

3.Modulatory influences of estradiol and other anorexigenic hormones on metabotropic, G_i/o-coupled receptor function in the hypothalamic control of energy homeostasis

作者：Virginia Mela^a ; Amanda Vargas^a ; Cecilia Meza^a ; Malika Kachani^b ; Edward J. Wagner^a ; ^{ewagner@westernu.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：2-AG ; 2-arachidonoylglycerol ; AgRP ; agouti-related peptide ; AMPK ; AMP-activated protein kinase ; ARC ; hypothalamic arcuate nucleus ; CRH ; corticotropin-releasing hormone ; DSI ; depolarization-induced suppression of inhibition ; ERK ; extracellular signal-regulated protein kinase ; GIRK ; G protein-gated ; inwardly-rectifying K+ ; JAK ; Janus kinase ; LHA ; lateral hypothalamic area ; MCH ; melanin-concentrating hormone ; mEPSC ; miniature excitatory postsynaptic current ; nNOS ; neuronal nitric oxide synthase ; NP

刊名：Journal of Steroid Biochemistry and Molecular Biology

出版年：2016

4.SORLA regulates calpain-dependent degradation of synapsin

作者：Daniela Hartl^a ; ^b ; ^{daniela.hartl@uniklinikum-saarland.de" class="auth_mail" title="E-mail the corresponding author} ; Grit Nebrich^a ; Oliver Klein^a ; Heike Stephanowitz^c ; Eberhard Krause^c ; Michael Rohe^d ; ^{michael.rohe@abbvie.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Alzheimer's disease ; Risk factor ; Sporadic AD ; SORLA ; Sorl1 ; Synapse

刊名：Alzheimer's & Dementia

出版年：2016

5.Activation of membrane estrogen receptors attenuates opioid receptor-like1 receptor-mediated antinociception via an ERK-dependent non-genomic mechanism

作者：K.M. Small ; S. Nag ; S.S. Mokha

关键词：ANOVA ; analysis of variance ; AUC ; area under the curve ; DPN ; diarylpropionitrile ; E2BSA ; 尾-estradiol-6-(O-carboxymethyl)oxime ; bovine serum albumin ; ERK ; extracellular signal-regulated kinase ; GIRK ; G protein-gated inwardly rectifying potassium channels ; Gq-mER ; Gq-coupled mER ; mERs ; membrane estrogen receptors ; OFQ ; orphanin FQ ; ORL1 ; opioid receptor-like 1 ; OVX ; ovariectomized ; PKA ; protein kinase A ; PKC ; protein kinase C ; PPT ; propylpyrazoletriol ; TFL ; tail flick latencies

刊名：Neuroscience

出版年：26 December, 2013

6.Quantitative structure activity relationship (QSAR) studies on a series of imidazole derivatives as novel ORL1 receptor antagonists

作者：A.K. Srivastava ; Neerja Shukla

关键词：QSAR ; ORL1 receptor antagonist ; Physicochemical property ; Regression analysis

刊名：Journal of Saudi Chemical Society

出版年：2013

7.Evaluation of [¹⁸F]MK-0911, a positron emission tomography (PET) tracer for opioid receptor-like 1 (ORL1), in rhesus monkey and human

作者：Eric D. Hostetler^a ; ^{eric_hostetler@merck.com} ; Sandra Sanabria-Bohó ; rquez^a ; Waisi Eng^a ; Aniket D. Joshi^a ; Shailendra Patel^a ; Raymond E. Gibson^a ; Stacey O'Malley^a ; Stephen M. Krause^a ; Christine Ryan^a ; Kerry Riffel^a ; Sheng Bi^a ; Osamu Okamoto^b ; Hiroshi Kawamoto^b ; Satoshi Ozaki^b ; Hisashi Ohta^b ; Tjibbe de Groot^c ; Guy Bormans^c ; Marleen Depré ; ^f ; Jan de Hoon^f ; Inge De Lepeleire^d ; Tom Reynders^d ; Jacquelynn J. Cook^a ; H. Donald Burns^a ; Michael Egan^e ; William Cho^e ; Koen van Laere^c ; Richard J. Hargreaves^a

关键词：Opioid receptor like-1 ; NOP ; PET ; Monkey ; Human ; Fluorine-18

刊名：NeuroImage

出版年：2013

8.The SORL1 polymorphism rs985421 may confer the risk for amnestic mild cognitive impairment and Alzheimer's disease in the Han Chinese population

作者：Chunhui Jin^a ; ^{jch1029@126.com" class="auth_mail} ; Lili Zhang^b ; Yiping Xian^c ; Xiaowei Liu^a ; Yue Wu^a ; Feng Zhang^a ; Jianzhong Zhu^a ; Guofu Zhang^a ; Caixia Chen^a ; Ronglan Gong^b ; Lingyun Zhang^b ; Jianmin Yuan^a ; Fuquan Zhang^a ; Lin Tian^a ; Guoqiang Wang^a ; Zaohuo Cheng^a ; ^{chengzaohuo@126.com" class="auth_mail}

关键词：Alzheimer's disease ; SORL1 ; Mild cognitive impairment ; Polymorphism ; Han Chinese

刊名：Neuroscience Letters

出版年：20 March, 2014

9.Association between the SORL1 rs2070045 polymorphism and late-onset Alzheimer's disease: Interaction with the ApoE genotype in the Chinese Han population

作者：Xiaofan Xue ; Milan Zhang ; Yicong Lin ; Erhe Xu ; Jianping Jia

关键词：Alzheimer's disease ; Sortilin-related receptor L1 ; Single nucleotide polymorphism ; Chinese ; ApoE

刊名：Neuroscience Letters

出版年：24 January, 2014

10.Acute and subchronic treatments with selective serotonin reuptake inhibitors increase Nociceptin/Orphanin FQ (NOP) receptor density in the rat dorsal raphe nucleus; interactions between nociceptin/NOP system and serotonin

作者：Erwan Le Maî ; tre¹ ; Nathalie Dourmap² ; Catherine Vilpoux³ ; Romain Leborgne ; Franç ; ois Janin² ; Jean-Jacques Bonnet ; Jean Costentin ; Isabelle Leroux-Nicollet ; ^{isabelle.leroux@univ-rouen.fr}

关键词：AUC ; area under the curve ; DOPAC ; dihydroxyphenylacetic acid ; DRN ; dorsal raphe nucleus ; HVA ; homovanillic acid ; NOP receptor ; nociceptin-orphanin FQ receptor ; ORL1 receptor ; opioid receptor-like 1 receptor ; pCPA ; para-chlorophenylalanine ; SSRI ; selective

刊名：Brain Research

出版年：2013

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