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CNKI期刊论文0611(2)
知网期刊论文(261)
在“
Elsevier电子期刊
”中,
命中:
154
条,耗时:小于0.01 秒
在所有数据库中总计命中:
931
条
1.
Rapid preparation of (3R,4S,5R) polyhydroxylated pyrrolidine-based libraries to discover a
pharmacological
chaperone
for treatment of Fabry disease
作者:
Wei-Chieh Cheng
a
;
b
;
wcheng@gate.sinica.edu.tw
;
Jen-Hon Wang
a
;
b
;
Wen-Yi Yun
a
;
Huang-Yi Li
a
;
Jia-Ming Hu
a
关键词:
Azasugar
;
Polyhydroxylated pyrrolidine
;
Fabry disease
;
Pharmacological
chaperone
;
Combinatorial chemistry
;
Lysosomal α-galactosidase
刊名:European Journal of Medicinal Chemistry
出版年:2017
2.
(5aR)-5a-C-Pentyl-4-epi-isofagomine: A powerful inhibitor of lysosomal β-galactosidase and a remarkable
chaperone
for mutations associated with GM1-gangliosidosis and Morquio disease type B
作者:
Sophie Front
a
;
Anna Biela-Banaś
a
;
Patricie Burda
b
;
Diana Ballhausen
c
;
Katsumi Higaki
d
;
Anna Caciotti
e
;
Amelia Morrone
e
;
f
;
Julie Charollais-Thoenig
g
;
Estelle Gallienne
a
;
Sté
;
phane Demotz
g
;
Olivier R. Martin
a
;
olivier.martin@univ-orleans.fr
关键词:
Galactosidase inhibitors
;
GM1-gangliosidosis
;
Morquio disease type B
;
Iminosugars
;
Pharmacological
chaperone
s
刊名:European Journal of Medicinal Chemistry
出版年:2017
3.
Bioevaluation of sixteen ADMDP stereoisomers toward alpha-galactosidase A: Development of a new
pharmacological
chaperone
for the treatment of Fabry disease and potential enhancement of enzyme replacement therapy efficiency
作者:
Wei-Chieh Cheng
a
;
b
;
wcheng@gate.sinica.edu.tw" class="auth_mail" title="E-mail the corresponding author
;
Jen-Hon Wang
a
;
b
;
Huang-Yi Li
a
;
Sheng-Jhih Lu
a
;
Jia-Ming Hu
a
;
Wen-Yi Yun
a
;
Cheng-Hsin Chiu
a
;
Wen-Bin Yang
a
;
Yin-Hsiu Chien
c
;
Wuh-Liang Hwu
c
关键词:
Fabry disease
;
Lysosomal α-galactosidase A
;
Lysosomal storage diseases
;
Enzyme replacement therapy
;
Pharmacological
chaperone
;
Pyrrolidine-based iminosugar
刊名:European Journal of Medicinal Chemistry
出版年:2016
4.
Kinetic stability of cystathionine beta-synthase can be modulated by structural analogs of S-adenosylmethionine: Potential approach to
pharmacological
chaperone
therapy for homocystinuria
作者:
Tomas Majtan
a
;
1
;
Angel L. Pey
b
;
1
;
angelpey@ugr.es" class="auth_mail" title="E-mail the corresponding author
;
Jan P. Kraus
a
;
jan.kraus@ucdenver.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Cystathionine beta-synthase
;
S-adenosylmethionine
;
Kinetic stability
;
Calorimetry
;
Pharmacological
chaperone
;
Homocystinuria
刊名:Biochimie
出版年:2016
5.
5-Fluoro derivatives of 4-epi-isofagomine as d-galactosidase inhibitors and potential
pharmacological
chaperone
s for G
M1
-gangliosidosis as well as Fabry's disease
作者:
Martin Thonhofer
a
;
Andres Gonzalez Santana
b
;
Roland Fischer
c
;
Ana Torvisco Gomez
c
;
Robert Saf
d
;
Michael Schalli
a
;
Arnold E. Stü
;
tz
a
;
stuetz@tugraz.at" class="auth_mail" title="E-mail the corresponding author
;
Stephen G. Withers
b
关键词:
Iminoalditol
;
Fluorosugar
;
Galactosidase inhibitor
;
Pharmacological
chaperone
;
Fabry's disease
;
GM1-gangliosidosis
刊名:Carbohydrate Research
出版年:2016
6.
Breaking BAG: The Co-
Chaperone
BAG3 in Health and Disease
作者:
Christian Behl
1
;
cbehl@uni-mainz.de" class="auth_mail" title="E-mail the corresponding author
关键词:
Bcl-2
;
Hsc/Hsp70
;
protein quality control
;
BAG1&ndash
;
BAG3 switch
;
proteasome
;
macroautophagy
刊名:Trends in
Pharmacological
Sciences
出版年:2016
7.
The non-detergent sulfobetaine-201 acts as a
pharmacological
chaperone
to promote folding and crystallization of the type II TGF-尾 receptor extracellular domain
作者:
Kittikhun Wangkanont
a
;
1
;
wangkanont@wisc.edu" class="auth_mail" title="E-mail the corresponding author
;
Katrina T. Forest
b
;
forest@bact.wisc.edu" class="auth_mail" title="E-mail the corresponding author
;
Laura L. Kiessling
a
;
c
;
kiessling@chem.wisc.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Non-detergent sulfobetaine 201
;
Transforming growth factor 尾
;
Type II transforming growth factor 尾 receptor
;
Protein folding
;
Pharmacological
chaperone
刊名:Protein Expression and Purification
出版年:2015
8.
Synthesis of C-5a-chain extended derivatives of 4-epi-isofagomine: Powerful β-galactosidase inhibitors and low concentration activators of G
M1
-gangliosidosis-related human lysosomal β-galactosidase
作者:
Martin Thonhofer
a
;
Patrick Weber
a
;
Andres Gonzalez Santana
b
;
Roland Fischer
c
;
Bettina M. Pabst
d
;
Eduard Paschke
d
;
Michael Schalli
a
;
Arnold E. Stü
;
tz
a
;
stuetz@tugraz.at" class="auth_mail" title="E-mail the corresponding author
;
Marion Tschernutter
d
;
Werner Windischhofer
d
;
Stephen G. Withers
b
关键词:
Iminoalditol
;
4-epi-Isofagomine
;
Galactosidase inhibitor
;
Pharmacological
chaperone
;
GM1-gangliosidosis
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
9.
Synthesis of C-5a-substituted derivatives of 4-epi-isofagomine: notable β-galactosidase inhibitors and activity promotors of G
M1
-gangliosidosis related human lysosomal β-galactosidase mutant R201C
作者:
Martin Thonhofer
a
;
Patrick Weber
a
;
Andres Gonzalez Santana
b
;
Christina Tysoe
b
;
Roland Fischer
c
;
Bettina M. Pabst
d
;
Eduard Paschke
d
;
Michael Schalli
a
;
Arnold E. Stü
;
tz
a
;
stuetz@tugraz.at" class="auth_mail" title="E-mail the corresponding author
;
Marion Tschernutter
d
;
Werner Windischhofer
d
;
Stephen G. Withers
b
关键词:
Iminoalditol
;
4-Epi-isofagomine
;
Galactosidase inhibitor
;
Pharmacological
chaperone
;
GM1-gangliosidosis
刊名:Carbohydrate Research
出版年:2016
10.
Co-administration of the
pharmacological
chaperone
AT2221 with a proprietary recombinant human acid alfa-glucosidase leads to greater plasma exposure and substrate reduction compared to alglucosidase alfa
作者:
Richie Khanna
;
Su Xu
;
Deborah Hilliard
;
Yi Lun
;
Adriane Schilling
;
Rebecca Soska
;
Anju Nair
;
Kate Chang
;
Jessie Feng
;
Michelle Frascella
;
Anadina Garcia
;
Kimberly Pendino
;
Franklin Johnson
;
Elfrida R. Benjamin
;
Russell Gotschall
;
Hung Do
;
Kenneth J. Valenzano
刊名:Molecular Genetics and Metabolism
出版年:2016
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