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内部出版物
在“
Elsevier电子期刊
”中,
命中:
6,684
条,耗时:小于0.01 秒
1.
The
Antisense
Transcript SMN-AS1 Regulates SMN Expression and Is a Novel Therapeutic Target for Spinal Muscular Atrophy
作者:
Constantin d&rsquo
;
Ydewalle
1
;
Daniel M. Ramos
2
;
Noah J. Pyles
1
;
Shi-Yan Ng
3
;
4
;
7
;
Mariusz Gorz
1
;
Celeste M. Pilato
1
;
Karen Ling
5
;
Lingling Kong
1
;
Amanda J. Ward
6
;
Lee L. Rubin
3
;
4
;
Frank Rigo
5
;
C. Frank Bennett
5
;
Charlotte J. Sumner
1
;
2
;
8
;
csumner1@jhmi.edu
关键词:
spinal muscular atrophy
;
SMN
;
long non-coding RNA
;
antisense
oligonucleotides
;
SMA therapeutics
刊名:Neuron
出版年:2017
2.
Strategies to identify natural
antisense
transcripts
作者:
Yulong Sun
a
;
Dijie Li
a
;
Ru Zhang
a
;
Shang Peng
a
;
Ge Zhang
b
;
Tuanmin Yang
c
;
doctoryangtm@163.com
;
Airong Qian
a
;
qianair@nwpu.edu.cn
关键词:
Natural
antisense
transcripts
;
Long noncoding RNA
;
RNA-Seq
;
Microarray
;
RNA-ChIP
;
RACE
刊名:Biochimie
出版年:2017
3.
Targeting nanocarriers containing
antisense
oligonucleotides to cancer cell
作者:
Parth Patel
;
parthpatel_11@ymail.com
;
Y.K. Agrawal
关键词:
Oncogene
;
Small interfering ribonucleic acid
;
Antisensing concept
;
Phagocyte
;
Nanoplex
;
Niosome
;
Immunostimulation
;
Bioimaging
刊名:Journal of Drug Delivery Science and Technology
出版年:2017
4.
Co-delivery of VP-16 and Bcl-2-targeted
antisense
on PEG-grafted oMWCNTs for synergistic in vitro anti-cancer effects in non-small and small cell lung cancer
作者:
Zbynek Heger
a
;
b
;
Hana Polanska
b
;
c
;
Sona Krizkova
a
;
b
;
Jan Balvan
b
;
c
;
Martina Raudenska
b
;
c
;
Simona Dostalova
a
;
b
;
Amitava Moulick
a
;
b
;
Michal Masarik
b
;
c
;
Vojtech Adam
a
;
b
;
vojtech.adam@mendelu.cz
关键词:
Drug delivery
;
Etoposide
;
In vitro release
;
Multi-walled carbon nanotubes
;
Nanomedicine
刊名:Colloids and Surfaces B: Biointerfaces
出版年:2017
5.
Lipid-modified oligonucleotide conjugates: Insights into gene silencing, interaction with model membranes and cellular uptake mechanisms
作者:
Begoñ
;
a Ugarte-Uribe
a
;
Santiago Grijalvo
b
;
c
;
Samuel Nú
;
ñ
;
ez Pertí
;
ñ
;
ez
b
;
Jon V. Busto
a
;
Cé
;
sar Martí
;
n
a
;
Adele Alagia
b
;
Fé
;
lix M. Goñ
;
i
a
;
Ramó
;
n Eritja
b
;
c
;
Itziar Alkorta
a
;
itzi.alkorta@ehu.es
关键词:
Antisense
technology
;
Cellular uptake
;
Gene delivery
;
Lipid&ndash
;
oligonucleotide conjugates
;
Model membrane systems
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
6.
Novel Targeted Therapies for Inflammatory Bowel Disease
作者:
Mehmet Coskun
1
;
2
;
Severine Vermeire
3
;
Ole Haagen Nielsen
1
;
ohn@dadlnet.dk
关键词:
antisense
therapy
;
biologics
;
Crohn's disease
;
leukocyte trafficking
;
small molecules
;
ulcerative colitis
刊名:Trends in Pharmacological Sciences
出版年:2017
7.
Exploring Splicing-Switching Molecules For Seckel Syndrome Therapy
作者:
Daniela Scalet
a
;
Dario Balestra
a
;
Sara Rohban
b
;
Matteo Bovolenta
a
;
Daniela Perrone
c
;
Francesco Bernardi
a
;
Stefano Campaner
b
;
Mirko Pinotti
a
;
pnm@unife.it
关键词:
(up to 6) Seckel syndrome-1
;
Exonic splicing silencer
;
modified U1snRNA
;
Antisense
oligonucleotide
;
correction approaches
刊名:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
出版年:2017
8.
Clinical potential of oligonucleotide-based therapeutics in the respiratory system
作者:
Sterghios A. Moschos
a
;
c
;
sterghios.moschos@northumbria.ac.uk
;
Louise Usher
a
;
Mark A. Lindsay
b
关键词:
AGO
;
Argonaute
;
ASO
;
antisense
oligonucleotide
;
CCR3
;
C&ndash
;
C chemokine receptor 3
;
CPP
;
cell penetrating peptide
;
COPD
;
chronic obstructive pulmonary disease
;
CD
;
cluster designation
;
GMCSF
;
granulocyte monocyte-colony stimulating factor
;
IL
;
interleukin
;
IL-&lsquo
;
X&rsquo
R ;
Interleukin receptor number &lsquo
;
X&rsquo
;
LNA
;
locked nucleic acid
;
miRNA
;
microRNA
;
ncRNA
;
non-coding RNA
;
nt
;
nucleotide
;
PNA
;
peptide nucleic acid
;
PMO
;
phosphorodiamidate morpholinos
;
RISC
;
RNA induced silencing c
刊名:Pharmacology & Therapeutics
出版年:2017
9.
Unravelling the nanostructure of strawberry fruit pectins by endo-polygalacturonase digestion and atomic force microscopy
作者:
Candelas Paniagua
a
;
Andrew R. Kirby
b
;
A. Patrick Gunning
b
;
Victor J. Morris
b
;
Antonio J. Matas
a
;
Miguel A. Quesada
c
;
José
;
A. Mercado
a
;
mercado@uma.es
关键词:
AFM
;
atomic force microscopy
;
APEL
;
antisense
pectate lyase plants
;
APG
;
antisense
polygalacturonase plants
;
HG
;
homogalacturonan
;
LN
;
number-average contour length
;
LW
;
weight-average contour length
;
PDI
;
polydispersity index
;
PG
;
polygalacturonase
;
PL
;
pectate lyase
;
RG
;
rhamnogalacturonan
;
XGA
;
xylogalacturonan
刊名:Food Chemistry
出版年:2017
10.
miRNases: Novel peptide-oligonucleotide bioconjugates that silence miR-21 in lymphosarcoma cells
作者:
Olga A. Patutina
a
;
Elena V. Bichenkova
b
;
elena.v.bichenkova@manchester.ac.uk
;
Svetlana K. Miroshnichenko
a
;
Nadezhda L. Mironova
a
;
Linda T. Trivoluzzi
b
;
Kepa K. Burusco
b
;
Richard A. Bryce
b
;
Valentin V. Vlassov
a
;
Marina A. Zenkova
a
;
marzen@niboch.nsc.ru
关键词:
Peptide-oligonucleotide conjugates
;
RNA cleavage
;
Antisense
oligonucleotides
;
Anti-miRNA therapy
;
Oncogenic miRNA
;
miR-21
刊名:Biomaterials
出版年:2017
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