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在“Elsevier电子期刊”中，命中：173条，耗时：0.0239886 秒

在所有数据库中总计命中：1,045条

1.Synthetic peptide antigens derived from long-chain alpha-neurotoxins: Immunogenicity effect against elapid venoms

作者：Guillermo de la Rosa^a ; Nina Pastor^b ; Alejandro Alagó ; n^a ; Gerardo Corzo^a ; ^{corzo@ibt.unam.mx}

关键词：Elapid antivenom ; Long-chain α-neurotoxins ; Snakebites ; Three-finger toxins

刊名：Peptides

出版年：2017

2.Design, synthesis and biological activity of novel molecules designed to target PARP and DNA

作者：Elliot Goodfellow^a ; Zhor Senhaji Mouhri^a ; Christopher Williams^b ; Bertrand J. Jean-Claude^a ; ^{bertrandj.jean-claude@mcgill.ca}

关键词：PARP inhibitors ; BRCA mutation ; Synthetic lethality ; DNA damage ; Bis-targeting

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

3.Arginine Deprivation Inhibits the Warburg Effect and Upregulates Glutamine Anaplerosis and Serine Biosynthesis in ASS1-Deficient Cancers

作者：Jeff Charles Kremer¹ ; Bethany Cheree Prudner¹ ; Sara Elaine Stubbs Lange¹ ; Gregory Richard Bean¹ ; Matthew Bailey Schultze¹ ; Caitlyn Brook Brashears¹ ; Megan DeAnna Radyk¹ ; Nathan Redlich¹ ; Shin-Cheng Tzeng² ; Kenjiro Kami³ ; Laura Shelton⁴ ; Aixiao Li⁵ ; Zack Morgan⁵ ; John Stephen Bomalaski⁶ ; Takashi Tsukamoto⁷ ; Jon McConathy⁵ ; ⁸ ; ⁹ ; Loren Scott Michel¹ ; ⁸ ; Jason Matthew Held² ; ⁸ ; ¹⁰ ; Brian Andrew Van Tine¹ ; ⁸ ; ¹¹ ; ^{bvantine@wustl.edu}

关键词：sarcoma ; cancer metabolism ; Warburg effect ; glutamine anaplerosis ; serine biosynthesis ; argininosuccinate synthetase 1 ; arginine deprivation ; serine ; arginine ; glutamine

刊名：Cell Reports

出版年：2017

4.Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities

作者：Kumar Sanjiv¹ ; Anna Hagenkort¹ ; José ; Manuel Calderó ; n-Montañ ; o¹ ; Tobias Koolmeister¹ ; Philip M. Reaper² ; Oliver Mortusewicz¹ ; Sylvain A. Jacques¹ ; Raoul V. Kuiper³ ; Niklas Schultz¹ ; Martin Scobie¹ ; Peter A. Charlton² ; John R. Pollard² ; Ulrika Warpman Berglund¹ ; Mikael Altun¹ ; Thomas Helleday¹ ; ^{thomas.helleday@scilifelab.se" class="auth_mail" title="E-mail the corresponding author}

关键词：ATR ; CHK1 ; synthetic lethality ; cancer ; DNA damage ; replication stress

刊名：Cell Reports

出版年：2016

5.Synthetic lethal approaches for assessing combinatorial efficacy of chemotherapeutic drugs

作者：Rebecca A. Jackson^a ; Ee Sin Chen^a ; ^b ; ^c ; ^d ; ^{bchces@nus.edu.sg" class="auth_mail" title="E-mail the corresponding author}

关键词：Synthetic lethality ; Epigenetics ; High-throughput screening ; Genomics ; Signaling networks

刊名：Pharmacology and Therapeutics

出版年：2016

6.Novel synthetic lethality screening method identifies TIP60-dependent radiation sensitivity in the absence of BAF180

作者：Suzanna R. Hopkins^a ; Grant A. McGregor^a ; Johanne M. Murray^a ; Jessica A. Downs^a ; Velibor Savic^a ; ^b ; ^{V.Savic@bsms.ac.uk" class="auth_mail" title="E-mail the corresponding author}

刊名：DNA Repair

出版年：2016

7.PARP-inhibitor-induced synthetic lethality for acute myeloid leukemia treatment

作者：Lu Zhao ; Chi Wai Eric So ; ^{eric.so@kcl.ac.uk" class="auth_mail" title="E-mail the corresponding author}

刊名：Experimental Hematology

出版年：2016

8.Network pharmacology of cancer: From understanding of complex interactomes to the design of multi-target specific therapeutics from nature

作者：Paramasivan Poornima^a ; ¹ ; Jothi Dinesh Kumar^b ; ¹ ; Qiaoli Zhao^c ; Martina Blunder^d ; Thomas Efferth^c ; ^{efferth@uni-mainz.de" class="auth_mail" title="E-mail the corresponding author}

关键词：Eleutherococcus senticosus ; Genomics ; Green tea polyphenolics ; Lithospermum erythrorhizon ; Metabolomics ; Polypharmacology ; Proteomics ; Rhodiola rosea ; Schisandra chinensis ; Synthetic lethality ; Systems biology ; Transcriptomics

刊名：Pharmacological Research

出版年：2016

9.Hypoxia Potentiates the Radiation-Sensitizing Effect of Olaparib in Human Non-Small Cell Lung Cancer Xenografts by Contextual Synthetic Lethality

作者：Yanyan Jiang ; PhD ; Tom Verbiest ; MSc ; Aoife M. Devery ; PhD ; Sivan M. Bokobza ; PhD ; Anika M. Weber ; PhD ; Katarzyna B. Leszczynska ; PhD ; Ester M. Hammond ; PhD ; Anderson J. Ryan ; PhD ; ^{anderson.ryan@oncology.ox.ac.uk" class="auth_mail" title="E-mail the corresponding author}

刊名：International Journal of Radiation Oncology*Biology*Physics

出版年：2016

10.Targeting Mismatch Repair defects: A novel strategy for personalized cancer treatment

作者：Rumena Begum ; Sarah A. Martin ; ^{sarah.martin@qmul.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：Mismatch Repair ; Therapies ; Synthetic lethality

刊名：DNA Repair

出版年：2016

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