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知网期刊论文(141)
在“
Elsevier电子期刊
”中,
命中:
127
条,耗时:小于0.01 秒
在所有数据库中总计命中:
466
条
1.
Identification of novel fluorescent probes preventing PrP
Sc
replication in prion diseases
作者:
Ludovica Zaccagnini
a
;
1
;
Simone Brogi
b
;
c
;
1
;
Margherita Brindisi
b
;
c
;
Sandra Gemma
b
;
c
;
gemma@unisi.it
;
Giulia Chemi
b
;
c
;
Giuseppe Legname
a
;
legname@sissa.it
;
Giuseppe Campiani
b
;
c
;
Stefania Butini
b
;
c
关键词:
Pharmacophore modeling
;
3D-QSAR
;
Prion
;
Anti-Prion agents
;
Theranostic tools
刊名:European Journal of Medicinal Chemistry
出版年:2017
2.
Soluble prion protein and its N-terminal fragment prevent impairment of synaptic plasticity by Aβ oligomers: Implications for novel therapeutic strategy in Alzheimer's disease
作者:
Jonah J. Scott-McKean
a
;
1
;
Krystyna Surewicz
b
;
1
;
Jin-Kyu Choi
b
;
Vernon A. Ruffin
b
;
2
;
Ahlam I. Salameh
b
;
Krzysztof Nieznanski
d
;
Alberto C.S. Costa
a
;
c
;
Witold K. Surewicz
b
;
witold.surewicz@case.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
PrPC
;
membrane-anchored cellular prion protein
;
rPrP
;
recombinant human prion protein
;
Aβ
;
amyloid β
;
GPI
;
glycosylphosphatidylinositol
;
LTP
;
long-term potentiation
;
LDH
;
lactate dehydrogenase
;
fEPSPs
;
field evoked postsynaptic potentials
;
aCSF
;
artificial cerebral spinal fluid
刊名:Neurobiology of Disease
出版年:2016
3.
Pathogenic Mutations within the Disordered Palindromic Region of the Prion Protein Induce Structure Therein and Accelerate the Formation of Misfolded Oligomers
作者:
A.T. Sabareesan
;
Jayant B. Udgaonkar
;
jayant@ncbs.res.in" class="auth_mail" title="E-mail the corresponding author
关键词:
PrPC
;
cellular prion protein
;
PrPSc
;
aggregated form of prion protein
;
NTR
;
N-terminal region
;
CTD
;
C-terminal domain
;
α2
;
helix 2
;
α3
;
helix 3
;
CD
;
circular dichroism
;
FTIR
;
Fourier transform infrared
;
DLS
;
dynamic light scattering
;
wt
;
wild-type
;
SEC
;
size-exclusion chromatography
;
HDX
;
hydrogen&ndash
;
deuterium exchange
;
MS
;
mass spectrometry
刊名:Journal of Molecular Biology
出版年:2016
4.
H ferritin silencing induces protein misfolding in K562 cells: A Raman analysis
作者:
Fabiana Zolea
a
;
1
;
Flavia Biamonte
a
;
1
;
Patrizio Candeloro
b
;
Maddalena Di Sanzo
a
;
Anna Cozzi
c
;
Anna Di Vito
a
;
Barbara Quaresima
a
;
Nadia Lobello
a
;
Francesca Trecroci
a
;
Enzo Di Fabrizio
b
;
d
;
Sonia Levi
c
;
e
;
Giovanni Cuda
a
;
2
;
Francesco Costanzo
a
;
2
;
fsc@unicz.it" class="auth_mail" title="E-mail the corresponding author
关键词:
2'-7'-DCF
;
2&rsquo
;
-7&rsquo
;
-dichlorodihydrofluorescein
;
AβP
;
β-amiloid protein
;
BCA
;
bicinchoninic acid
;
CM-H2CFDA
;
5-(and-6)-carboxy-2&rsquo
;
7&rsquo
;
dichlorofluorescein
;
DCDR
;
drop coating deposition Raman
;
EMSC
;
extended multiplicative signal correction
;
FHC
;
ferritin heavy chain
;
Fth
;
ferritin H gene
;
Ftl
;
ferritin L gene
;
FtMt
;
ferritin mitochondrial
;
H-bonds
;
hydrogen bonds
;
HBSS
;
Hanks balanced saline solution
;
H-π
;
π hydrogen
;
PD
;
Parkinson's disease
;
PFA
;
paraformaldehyde
;
PrPc
;
prion
刊名:Free Radical Biology and Medicine
出版年:2015
5.
Structure-activity analysis and antiprion mechanism of isoprenoid compounds
作者:
Taichi Hamanaka
;
Keiko Nishizawa
;
Yuji Sakasegawa
;
Kenta Teruya
;
Katsumi Doh-ura
;
doh-ura@med.tohoku.ac.jp" class="auth_mail" title="E-mail the corresponding author
关键词:
PrP
;
prion protein
;
PrPc
;
normal cellular PrP
;
PrPres
;
protease-resistant abnormal PrP
;
JH-III
;
juvenile hormone III
;
FOH
;
farnesol
;
GGOH
;
geranylgeraniol
刊名:Virology
出版年:2015
6.
Association of prion protein genotype and scrapie prion protein type with cellular prion protein charge isoform profiles in cerebrospinal fluid of humans with sporadic or familial prion diseases
作者:
Matthias Schmitz
;
Katharina L眉llmann
;
Saima Zafar
;
Elisabeth Ebert
;
Marie Wohlhage
;
Panteleimon Oikonomou
;
Markus Schlomm
;
Eva Mitrova
;
Michael Beekes
;
Inga Zerr
关键词:
Biomarker
;
Creutzfeldt-Jakob disease
;
PrPC
charge isoforms
;
Truncated
PrPC
forms
刊名:Neurobiology of Aging
出版年:May, 2014
7.
3D local structure around copper site of rabbit prion-related protein: Quantitative determination by XANES spectroscopy combined with multiple-scattering calculations
作者:
P.X. Cui
;
F.L. Lian
;
Y. Wang
;
Yi Wen
;
W.S. Chu
;
H.F. Zhao
;
S. Zhang
;
J. Li
;
D.H. Lin
;
Z.Y. Wu
关键词:
PrP
;
prion-related protein
;
TSE
;
transmissible spongiform encephalopathies
;
PrPC
;
cellular prion protein
;
PrPSc
;
scrapie prion protein
;
Ra
PrPC
;
rabbit prion protein
;
XANES
;
X-ray absorption near-edge structure
;
EXAFS
;
extended X-ray absorption fine structure
;
MS
;
multiple scattering
;
MXAN
;
Minuit XANES
;
a software package to reconstruct 3D structures from XANES spectra
;
XAS
;
X-ray absorption spectra
;
MT
;
muffin-tin
;
FT
;
Fourier transform
刊名:Radiation Physics and Chemistry
出版年:February, 2014
8.
A label-free electrical impedimetric biosensor for the specific detection of Alzheimer's amyloid-beta oligomers
作者:
Jo V. Rushworth
a
;
j.v.h.rushworth@leeds.ac.uk" class="auth_mail
;
Asif Ahmed
a
;
Heledd H. Griffiths
b
;
Niall M. Pollock
b
;
Nigel M. Hooper
b
;
Paul A. Millner
a
关键词:
A尾
;
amyloid-beta
;
A尾O
;
amyloid-beta oligomers
;
AD
;
Alzheimer's disease
;
APP
;
amyloid precursor protein
;
CSF
;
cerebro-spinal fluid
;
EIS
;
electrochemical impedance spectroscopy
;
LTP
;
long-term potentiation
;
POPA
;
co-polymer formed from tyramine and 3-(4-hydroxyphenyl) propionic acid
;
PrPC
;
cellular prion protein
刊名:Biosensors and Bioelectronics
出版年:15 June, 2014
9.
Novel compounds lowering the cellular isoform of the human prion protein in cultured human cells
作者:
B. Michael Silber
a
;
b
;
c
;
&dagger
;
;
Joel R. Gever
a
;
b
;
Satish Rao
a
;
b
;
&Dagger
;
;
Zhe Li
a
;
b
;
§
;
;
Adam R. Renslo
d
;
e
;
Kartika Widjaja
a
;
Casper Wong
a
;
Kurt Giles
a
;
b
;
Yevgeniy Freyman
a
;
Manuel Elepano
a
;
John J. Irwin
e
;
¶
;
;
Matthew P. Jacobson
a
;
e
;
Stanley B. Prusiner
a
;
b
;
stanley@ind.ucsf.edu" class="auth_mail
关键词:
IP
;
intraperitoneal
;
PO
;
per os (oral)
;
PrPC
;
cellular prion protein
;
PrPSc
;
disease-causing prion protein isoform
;
SPC
;
single point confirmation
刊名:Bioorganic and Medicinal Chemistry
出版年:15 March, 2014
10.
Molecular Dynamics Study of Conserved Water Molecules in
PrPc
and Pathological Point Mutation T188R
作者:
Katsufumi Tomobe
;
Eiji Yamamoto
;
Takuma Akimoto
;
Masato Yasui
;
Kenji Yasuoka
刊名:Biophysical Journal
出版年:28 January, 2014
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