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在“ACS电子期刊”中，命中：6条，耗时：0.0209855 秒

在所有数据库中总计命中：725条

1.Optimization of a Series of Bivalent Triazolopyridazine Based Bromodomain and Extraterminal Inhibitors: The Discovery of (3R)-4-[2-[4-[1-(3-Methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-4-piperidyl]phenoxy]ethyl]-1,3-dimethyl-piperazin-2-one (AZD5153)

作者：Robert H. Bradbury ; Rowena Callis ; Gregory R. Carr ; Huawei Chen ; Edwin Clark ; Lyman Feron ; Steve Glossop ; Mark A. Graham ; Maureen Hattersley ; Chris Jones ; Scott G. Lamont ; Gilles Ouvry ; Anil Patel ; Joe Patel ; Alfred A. Rabow ; Craig A. Roberts ; Stephen Stokes ; Natalie Stratton ; Graeme E. Walker ; Lara Ward ; David Whalley ; David Whittaker ; Gail Wrigley ; Michael J. Waring

刊名：Journal of Medicinal Chemistry

出版年：2016

2.Discovery and Characterization of MAPK-activated Protein Kinase-2 Prevention of Activation Inhibitors

作者：John G. Cumming ; Judit 脡. Debreczeni ; Fredrik Edfeldt ; Emma Evertsson ; Martin Harrison ; Geoffrey A. Holdgate ; Michael J. James ; Scott G. Lamont ; Keith Oldham ; Jane E. Sullivan ; Stuart L. Wells

刊名：Journal of Medicinal Chemistry

出版年：2015

3.Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and O

作者：Chris De Savi ; Robert H. Bradbury ; Alfred A. Rabow ; Richard A. Norman ; Camila de Almeida ; David M. Andrews ; Peter Ballard ; David Buttar ; Rowena J. Callis ; Gordon S. Currie ; Jon O. Curwen ; Chris D. Davies ; Craig S. Donald ; Lyman J. L. Feron ; Helen Gingell ; Steven C. Glossop ; Barry R. Hayter ; Syeed Hussain ; Galith Karoutchi ; Scott G. Lamont ; Philip MacFaul ; Thomas A. Moss ; Stuart E. Pearson ; Michael Tonge ; Graeme E. Walker ; Hazel M. Weir ; Zena Wilson

刊名：Journal of Medicinal Chemistry

出版年：2015

4.Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3

作者：Scott Boyd ; Joanna L. Brookfield ; Susan E. Critchlow ; Iain A. Cumming ; Nicola J. Curtis ; Judit Debreczeni ; S茅bastien L. Degorce ; Craig Donald ; Nicola J. Evans ; Sam Groombridge ; Philip Hopcroft ; Neil P. Jones ; Jason G. Kettle ; Scott Lamont ; Hilary J. Lewis ; Philip MacFaull ; Sheila B. McLoughlin ; Laurent J. M. Rigoreau ; James M. Smith ; Steve St-Gallay ; Julie K. Stock ; Andrew P. Turnbull ; Edward R. Wheatley ; Jon Winter ; Jonathan Wingfield

刊名：Journal of Medicinal Chemistry

出版年：2015

5.Discovery of a Potent and Selective EGFR Inhibitor (AZD9291) of Both Sensitizing and T790M Resistance Mutations That Spares the Wild Type Form of the Receptor

作者：M. Raymond V. Finlay ; Mark Anderton ; Susan Ashton ; Peter Ballard ; Paul A. Bethel ; Matthew R. Box ; Robert H. Bradbury ; Simon J. Brown ; Sam Butterworth ; Andrew Campbell ; Christopher Chorley ; Nicola Colclough ; Darren A. E. Cross ; Gordon S. Currie ; Matthew Grist ; Lorraine Hassall ; George B. Hill ; Daniel James ; Michael James ; Paul Kemmitt ; Teresa Klinowska ; Gillian Lamont ; Scott G. Lamont ; Nathaniel Martin ; Heather L. McFarland ; Martine J. Mellor ; Jonathon P. Orme ; David Perkins ; Paula Perkins ; Graham Richmond ; Peter Smith ; Richard A. Ward ; Michael J. Waring ; David Whittaker ; Stuart Wells ; Gail L. Wrigley

刊名：Journal of Medicinal Chemistry

出版年：2014

6.Amine-Promoted, Organocatalytic Aziridination of Enones

作者：Alan Armstrong ; Carl A. Baxter ; Scott G. Lamont ; Andrew R. Pape ; Richard Wincewicz

刊名：Organic Letters

出版年：2007

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