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SpringerLink电子期刊(3)
NATURE电子期刊(3)
Elsevier电子期刊(8)
ACS电子期刊(7)
在“
ACS电子期刊
”中,
命中:
7
条,耗时:小于0.01 秒
在所有数据库中总计命中:
21
条
1.
The Rational Design of Selective Benzoxazepin Inhibitors of the α-Isoform of Phosphoinositide 3-Kinase Culminating in the Identification of (S)-2-((2-(1-Isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydroben
作者:
Timothy P. Heffron
;
Robert A. Heald
;
Chudi Ndubaku
;
BinQing
Wei
;
Martin Augistin
;
Steven Do
;
Kyle Edgar
;
Charles Eigenbrot
;
Lori Friedman
;
Emanuela Gancia
;
Philip S. Jackson
;
Graham Jones
;
Aleksander Kolesnikov
;
Leslie B. Lee
;
John D. Lesnick
;
Cristina Lewis
;
Neville McLean
;
Mario M?rtl
;
Jim Nonomiya
;
Jodie Pang
;
Steve Price
;
Wei
Wei Prior
;
Laurent Salphati
;
Steve Sideris
;
Steven T. Staben
;
Stefan Steinbacher
;
Vickie Tsui
;
Jeffrey Wallin
;
Deepak Sampath
;
Alan G. Olivero
刊名:Journal of Medicinal Chemistry
出版年:2016
2.
Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice
作者:
Hans E. Purkey
;
Kirk Robarge
;
Jinhua Chen
;
Zhongguo Chen
;
Laura B. Corson
;
Charles Z. Ding
;
Antonio G. DiPasquale
;
Peter S. Dragovich
;
Charles Eigenbrot
;
Marie Evangelista
;
Benjamin P. Fauber
;
Zhenting Gao
;
Hongxiu Ge
;
Anna Hitz
;
Qunh Ho
;
Sharada S. Labadie
;
Kwong Wah Lai
;
Wenfeng Liu
;
Yajing Liu
;
Chiho Li
;
Shuguang Ma
;
Shiva Malek
;
Thomas O’Brien
;
Jodie Pang
;
David Peterson
;
Laurent Salphati
;
Steve Sideris
;
Mark Ultsch
;
BinQing
Wei
;
Ivana Yen
;
Qin Yue
;
Huihui Zhang
;
Aihe Zhou
刊名:ACS Medicinal Chemistry Letters
出版年:2016
3.
Discovery of 2-{3-[2-(1-Isopropyl-3-methyl-1H-1,2鈥?-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl]-1H-pyrazol-1-yl}-2-methylpropanamide (GDC-0032): A 尾-Sparing
作者:
Chudi O. Ndubaku
;
Timothy P. Heffron
;
Steven T. Staben
;
Matthew Baumgardner
;
Nicole Blaquiere
;
Erin Bradley
;
Richard Bull
;
Steven Do
;
Jennafer Dotson
;
Danette Dudley
;
Kyle A. Edgar
;
Lori S. Friedman
;
Richard Goldsmith
;
Robert A. Heald
;
Aleksandr Kolesnikov
;
Leslie Lee
;
Cristina Lewis
;
Michelle Nannini
;
Jim Nonomiya
;
Jodie Pang
;
Steve Price
;
Wei
Wei Prior
;
Laurent Salphati
;
Steve Sideris
;
Jeffery J. Wallin
;
Lan Wang
;
BinQing
Wei
;
Deepak Sampath
;
Alan G. Olivero
刊名:Journal of Medicinal Chemistry
出版年:2013
4.
Discovery of Novel PI3-Kinase 未 Specific Inhibitors for the Treatment of Rheumatoid Arthritis: Taming CYP3A4 Time-Dependent Inhibition
作者:
Brian S. Safina
;
Stewart Baker
;
Matt Baumgardner
;
Paul M. Blaney
;
Bryan K. Chan
;
Yung-Hsiang Chen
;
Matthew W. Cartwright
;
Georgette Castanedo
;
Christine Chabot
;
Arnaud J. Cheguillaume
;
Paul Goldsmith
;
David M. Goldstein
;
Bindu Goyal
;
Timothy Hancox
;
Raj K. Handa
;
Pravin S Iyer
;
Jasmit Kaur
;
Rama Kondru
;
Jane R. Kenny
;
Sussie L. Krintel
;
Jun Li
;
John Lesnick
;
Matthew C. Lucas
;
Cristina Lewis
;
Sophie Mukadam
;
Jeremy Murray
;
Alan J. Nadin
;
Jim Nonomiya
;
Fernando Padilla
;
Wylie S. Palmer
;
Jodie Pang
;
Neil Pegg
;
Steve Price
;
Karin Reif
;
Laurent Salphati
;
Pascal A. Savy
;
Eileen M. Seward
;
Stephen Shuttleworth
;
Sukhjit Sohal
;
Zachary K. Sweeney
;
Suzanne Tay
;
Parcharee Tivitmahaisoon
;
Bohdan Waszkowycz
;
Binqing
Wei
;
Qin Yue
;
Chenghong Zhang
;
Daniel P. Sutherlin
刊名:Journal of Medicinal Chemistry
出版年:2012
5.
Discovery and Optimization of a Novel Spiropyrrolidine Inhibitor of 尾-Secretase (BACE1) through Fragment-Based Drug Design
作者:
Ivan V. Efremov
;
Felix F. Vajdos
;
Kris A. Borzilleri
;
Steven Capetta
;
Hou Chen
;
Peter H. Dorff
;
Jason K. Dutra
;
Steven W. Goldstein
;
Mahmoud Mansour
;
Alexander McColl
;
Stephen Noell
;
Christine E. Oborski
;
Thomas N. O鈥機onnell
;
Theresa J. O鈥橲ullivan
;
Jayvardhan Pandit
;
Hong Wang
;
BinQing
Wei
;
Jane M. Withka
刊名:Journal of Medicinal Chemistry
出版年:2012
6.
Discovery of a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor (GDC-0980) for the Treatment of Cancer
作者:
Daniel P. Sutherlin
;
Linda Bao
;
Megan Berry
;
Georgette Castanedo
;
Irina Chuckowree
;
Jenna Dotson
;
Adrian Folks
;
Lori Friedman
;
Richard Goldsmith
;
Janet Gunzner
;
Timothy Heffron
;
John Lesnick
;
Cristina Lewis
;
Simon Mathieu
;
Jeremy Murray
;
Jim Nonomiya
;
Jodie Pang
;
Niel Pegg
;
Wei
Wei Prior
;
Lionel Rouge
;
Laurent Salphati
;
Deepak Sampath
;
Qingping Tian
;
Vickie Tsui
;
Nan Chi Wan
;
Shumei Wang
;
BinQing
Wei
;
Christian Wiesmann
;
Ping Wu
;
Bing-Yan Zhu
;
Alan Olivero
刊名:Journal of Medicinal Chemistry
出版年:2011
7.
Rational Design of Phosphoinositide 3-Kinase 伪 Inhibitors That Exhibit Selectivity over the Phosphoinositide 3-Kinase 尾 Isoform
作者:
Timothy P. Heffron
;
BinQing
Wei
;
Alan Olivero
;
Steven T. Staben
;
Vickie Tsui
;
Steven Do
;
Jennafer Dotson
;
Adrian J. Folkes
;
Paul Goldsmith
;
Richard Goldsmith
;
Janet Gunzner
;
John Lesnick
;
Cristina Lewis
;
Simon Mathieu
;
Jim Nonomiya
;
Stephen Shuttleworth
;
Daniel P. Sutherlin
;
Nan Chi Wan
;
Shumei Wang
;
Christian Wiesmann
;
Bing-Yan Zhu
刊名:Journal of Medicinal Chemistry
出版年:2011
1
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