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SpringerLink电子期刊(1)
Elsevier电子期刊(3)
ACS电子期刊(14)
在“
ACS电子期刊
”中,
命中:
14
条,耗时:小于0.01 秒
在所有数据库中总计命中:
18
条
1.
Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants
作者:
Hengmiao Cheng
;
Sajiv K. Nair
;
Brion W. Murray
;
Chau Almaden
;
Simon Bailey
;
Sangita Baxi
;
Doug Behenna
;
Sujin Cho-Schultz
;
Deepak
Dalvie
;
Dac M. Dinh
;
Martin P. Edwards
;
Jun Li Feng
;
Rose Ann Ferre
;
Ketan S. Gajiwala
;
Michelle D. Hemkens
;
Amy Jackson-Fisher
;
Mehran Jalaie
;
Ted O. Johnson
;
Robert S. Kania
;
Susan Kephart
;
Jennifer Lafontaine
;
Beth Lunney
;
Kevin K.-C. Liu
;
Zhengyu Liu
;
Jean Matthews
;
Asako Nagata
;
Sherry Niessen
;
Martha A. Ornelas
;
Suvi T. M. Orr
;
Mason Pairish
;
Simon Planken
;
Shijian Ren
;
Daniel Richter
;
Kevin Ryan
;
Neal Sach
;
Hong Shen
;
Tod Smeal
;
Jim Solowiej
;
Scott Sutton
;
Khanh Tran
;
Elaine Tseng
;
William Vernier
;
Marlena Walls
;
Shuiwang Wang
;
Scott L. Weinrich
;
Shuibo Xin
;
Haiwei Xu
;
Min-Jean Yin
;
Michael Zientek
;
Ru Zhou
;
John C. Kath
刊名:Journal of Medicinal Chemistry
出版年:2016
2.
A Simple Litmus Test for Aldehyde Oxidase Metabolism of Heteroarenes
作者:
Fionn O鈥橦ara
;
Aaron C. Burns
;
Michael R. Collins
;
Deepak
Dalvie
;
Martha A. Ornelas
;
Alfin D. N. Vaz
;
Yuta Fujiwara
;
Phil S. Baran
刊名:Journal of Medicinal Chemistry
出版年:2014
3.
Design and Synthesis of Novel N-Hydroxy-Dihydronaphthyridinones as Potent and Orally Bioavailable HIV-1 Integrase Inhibitors
作者:
Ted W. Johnson
;
Steven P. Tanis
;
Scott L. Butler
;
Deepak
Dalvie
;
Dorothy M. DeLisle
;
Klaus R. Dress
;
Erik J. Flahive
;
Qiyue Hu
;
Jon E. Kuehler
;
Atsuo Kuki
;
Wen Liu
;
Guy A. McClellan
;
Qinghai Peng
;
Michael B. Plewe
;
Paul F. Richardson
;
Graham L. Smith
;
Jim Solowiej
;
Khanh T. Tran
;
Hai Wang
;
Xiaoming Yu
;
Junhu Zhang
;
Huichun Zhu
刊名:Journal of Medicinal Chemistry
出版年:2011
4.
Aldehyde Oxidase: An Enzyme of Emerging Importance in Drug Discovery
作者:
David C. Pryde
;
Deepak
Dalvie
;
Qiyue Hu
;
Peter Jones
;
R. Scott Obach
;
Thien-Duc Tran
刊名:Journal of Medicinal Chemistry
出版年:2010
5.
Bioactivation of Lumiracoxib by Peroxidases and Human Liver Microsomes: Identification of Multiple Quinone Imine Intermediates and GSH Adducts
作者:
Ping Kang
;
Deepak
Dalvie
;
Evan Smith
;
Matt Renner
刊名:Chemical Research in Toxicology
出版年:2009
6.
A Holistic Strategy for Characterizing the Safety of Metabolites through Drug Discovery and Development
作者:
Don Walker
;
Joe Brady
;
Deepak
Dalvie
;
John Davis
;
Martin Dowty
;
J. Neil Duncan
;
Angus Nedderman
;
R. Scott Obach
;
Pat Wright
刊名:Chemical Research in Toxicology
出版年:2009
7.
Assessment of Three Human in Vitro Systems in the Generation of Major Human Excretory and Circulating Metabolites
作者:
Deepak
Dalvie
*
†
;
;
R. Scott Obach
‡
;
;
Ping Kang
†
;
;
Chandra Prakash
‡
;
;
Cho-Ming Loi
†
;
;
Susan Hurst
‡
;
刊名:Chemical Research in Toxicology
出版年:2009
8.
Effect of Intestinal Glucuronidation in Limiting Hepatic Exposure and Bioactivation of Raloxifene in Humans and Rats
作者:
Deepak
Dalvie
;
Ping Kang
;
Michael Zientek
;
Cathie Xiang
;
Sue Zhou
;
R. Scott Obach
刊名:Chemical Research in Toxicology
出版年:2008
9.
NADPH-Dependent Covalent Binding of [3H]Paroxetine to Human Liver Microsomes and S-9 Fractions: Identification of an Electrophilic Quinone Metabolite of Paroxetine
作者:
Sabrina X. Zhao
;
Deepak
K.
Dalvie
;
Joan M. Kelly
;
John R. Soglia
;
Kosea S. Frederick
;
Evan B. Smith
;
R. Scott Obach
;
Amit S. Kalgutkar
刊名:Chemical Research in Toxicology
出版年:2007
10.
Biotransformation Reactions of Five-Membered Aromatic Heterocyclic Rings
作者:
Deepak
K.
Dalvie
;
Amit S. Kalgutkar
;
S. Cyrus Khojasteh-Bakht
;
R. Scott Obach
;
and John P. O'Donnell
刊名:Chemical Research in Toxicology
出版年:2002
1
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