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ACS电子期刊(4)
在“
ACS电子期刊
”中,
命中:
4
条,耗时:小于0.01 秒
在所有数据库中总计命中:
4
条
1.
Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates
作者:
Mihirbaran Mandal
;
Yusheng Wu
;
Jeffrey Misiaszek
;
Guoqing Li
;
Alexei Buevich
;
John P. Caldwell
;
Xiaoxiang Liu
;
Robert D. Mazzola
;
Peter Orth
;
Corey Strickland
;
Johannes Voigt
;
Hongwu Wang
;
Zhaoning Zhu
;
Xia Chen
;
Michael Grzelak
;
Lynn A. Hyde
;
Reshma Kuvelkar
;
Prescott T. Leach
;
Giuseppe Terracina
;
Lili Zhang
;
Qi Zhang
;
Maria S. Michener
;
Brad Smith
;
Kathleen Cox
;
Diane Grotz
;
Leonard Favreau
;
Kaushik Mitra
;
Irina
Kazakevich
;
Brian A. McKittrick
;
William Greenlee
;
Matthew E. Kennedy
;
Eric M. Parker
;
Jared N. Cumming
;
Andrew W. Stamford
刊名:Journal of Medicinal Chemistry
出版年:2016
2.
Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931)–A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer’s Disease
作者:
Jack D. Scott
;
Sarah W. Li
;
Andrew P. J. Brunskill
;
Xia Chen
;
Kathleen Cox
;
Jared N. Cumming
;
Mark Forman
;
Eric J. Gilbert
;
Robert A. Hodgson
;
Lynn A. Hyde
;
Qin Jiang
;
Ulrich Iserloh
;
Irina
Kazakevich
;
Reshma Kuvelkar
;
Hong Mei
;
John Meredith
;
Jeffrey Misiaszek
;
Peter Orth
;
Lana M. Rossiter
;
Meagan Slater
;
Julie Stone
;
Corey O. Strickland
;
Johannes H. Voigt
;
Ganfeng Wang
;
Hongwu Wang
;
Yusheng Wu
;
William J. Greenlee
;
Eric M. Parker
;
Matthew E. Kennedy
;
Andrew W. Stamford
刊名:Journal of Medicinal Chemistry
出版年:2016
3.
Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation
作者:
Mihirbaran Mandal
;
Zhaoning Zhu
;
Jared N. Cumming
;
Xiaoxiang Liu
;
Corey Strickland
;
Robert D. Mazzola
;
John P. Caldwell
;
Prescott Leach
;
Michael Grzelak
;
Lynn Hyde
;
Qi Zhang
;
Giuseppe Terracina
;
Lili Zhang
;
Xia Chen
;
Reshma Kuvelkar
;
Matthew E. Kennedy
;
Leonard Favreau
;
Kathleen Cox
;
Peter Orth
;
Alexei Buevich
;
Johannes Voigt
;
Hongwu Wang
;
Irina
Kazakevich
;
Brian A. McKittrick
;
William Greenlee
;
Eric M. Parker
;
Andrew W. Stamford
刊名:Journal of Medicinal Chemistry
出版年:2012
4.
Cyclic Hydroxyamidines as Amide Isosteres: Discovery of Oxadiazolines and Oxadiazines as Potent and Highly Efficacious 纬-Secretase Modulators in Vivo
作者:
Zhong-Yue Sun
;
Theodros Asberom
;
Thomas Bara
;
Chad Bennett
;
Duane Burnett
;
Inhou Chu
;
John Clader
;
Mary Cohen-Williams
;
David Cole
;
Michael Czarniecki
;
James Durkin
;
Gioconda Gallo
;
William Greenlee
;
Hubert Josien
;
Xianhai Huang
;
Lynn Hyde
;
Nicholas Jones
;
Irina
Kazakevich
;
Hongmei Li
;
Xiaoxiang Liu
;
Julie Lee
;
Malcolm MacCoss
;
Mihir B. Mandal
;
Troy McCracken
;
Amin Nomeir
;
Robert Mazzola
;
Anandan Palani
;
Eric M. Parker
;
Dmitri A. Pissarnitski
;
Jun Qin
;
Lixin Song
;
Giuseppe Terracina
;
Monica Vicarel
;
Johannes Voigt
;
Ruo Xu
;
Lili Zhang
;
Qi Zhang
;
Zhiqiang Zhao
;
Xiaohong Zhu
;
Zhaoning Zhu
刊名:Journal of Medicinal Chemistry
出版年:2012
1
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