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Elsevier电子期刊(17)
ACS电子期刊(12)
在“
ACS电子期刊
”中,
命中:
12
条,耗时:0.0829909 秒
在所有数据库中总计命中:
29
条
1.
Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates
作者:
Mihirbaran M
and
al
;
Yusheng Wu
;
Jeffrey Misiaszek
;
Guoqing Li
;
Alexei Buevich
;
John P. Caldwell
;
Xiaoxiang Liu
;
Robert D. Mazzola
;
Peter Orth
;
Corey Strickl
and
;
Johannes Voigt
;
Hongwu Wang
;
Zhaoning
Zhu
;
Xia Chen
;
Michael Grzelak
;
Lynn A. Hyde
;
Reshma Kuvelkar
;
Prescott T. Leach
;
Giuseppe Terracina
;
Lili Zhang
;
Qi Zhang
;
Maria S. Michener
;
Brad Smith
;
Kathleen Cox
;
Diane Grotz
;
Leonard Favreau
;
Kaushik Mitra
;
Irina Kazakevich
;
Brian A. McKittrick
;
William Greenlee
;
Matthew E. Kennedy
;
Eric M. Parker
;
Jared N. Cumming
;
And
rew W. Stamford
刊名:Journal of Medicinal Chemistry
出版年:2016
2.
Synthesis
and
SAR Studies of Fused Oxadiazines as 纬-Secretase Modulators for Treatment of Alzheimer's Disease
作者:
Xianhai Huang
;
Wei Zhou
;
Xiaoxiang Liu
;
Hongmei Li
;
George Sun
;
Mihirbaran M
and
al
;
Monica Vicarel
;
Xiaohong
Zhu
;
Chad Bennett
;
Troy McCraken
;
Dmitri Pissarnitski
;
Zhiqiang Zhao
;
David Cole
;
Gioconda Gallo
;
Zhaoning
Zhu
;
An
and
an Palani
;
Robert Aslanian
;
John Clader
;
Michael Czarniecki
;
William Greenlee
;
Duane Burnett
;
Mary Cohen-Williams
;
Lynn Hyde
;
Lixin Song
;
Lili Zhang
;
Inhou Chu
;
Alexei Buevich
刊名:ACS Medicinal Chemistry Letters
出版年:2012
3.
Design
and
Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation
作者:
Mihirbaran M
and
al
;
Zhaoning
Zhu
;
Jared N. Cumming
;
Xiaoxiang Liu
;
Corey Strickl
and
;
Robert D. Mazzola
;
John P. Caldwell
;
Prescott Leach
;
Michael Grzelak
;
Lynn Hyde
;
Qi Zhang
;
Giuseppe Terracina
;
Lili Zhang
;
Xia Chen
;
Reshma Kuvelkar
;
Matthew E. Kennedy
;
Leonard Favreau
;
Kathleen Cox
;
Peter Orth
;
Alexei Buevich
;
Johannes Voigt
;
Hongwu Wang
;
Irina Kazakevich
;
Brian A. McKittrick
;
William Greenlee
;
Eric M. Parker
;
And
rew W. Stamford
刊名:Journal of Medicinal Chemistry
出版年:2012
4.
Cyclic Hydroxyamidines as Amide Isosteres: Discovery of Oxadiazolines
and
Oxadiazines as Potent
and
Highly Efficacious 纬-Secretase Modulators in Vivo
作者:
Zhong-Yue Sun
;
Theodros Asberom
;
Thomas Bara
;
Chad Bennett
;
Duane Burnett
;
Inhou Chu
;
John Clader
;
Mary Cohen-Williams
;
David Cole
;
Michael Czarniecki
;
James Durkin
;
Gioconda Gallo
;
William Greenlee
;
Hubert Josien
;
Xianhai Huang
;
Lynn Hyde
;
Nicholas Jones
;
Irina Kazakevich
;
Hongmei Li
;
Xiaoxiang Liu
;
Julie Lee
;
Malcolm MacCoss
;
Mihir B. M
and
al
;
Troy McCracken
;
Amin Nomeir
;
Robert Mazzola
;
An
and
an Palani
;
Eric M. Parker
;
Dmitri A. Pissarnitski
;
Jun Qin
;
Lixin Song
;
Giuseppe Terracina
;
Monica Vicarel
;
Johannes Voigt
;
Ruo Xu
;
Lili Zhang
;
Qi Zhang
;
Zhiqiang Zhao
;
Xiaohong
Zhu
;
Zhaoning
Zhu
刊名:Journal of Medicinal Chemistry
出版年:2012
5.
Discovery of an Orally Available, Brain Penetrant BACE1 Inhibitor That Affords Robust CNS A尾 Reduction
作者:
And
rew W. Stamford
;
Jack D. Scott
;
Sarah W. Li
;
Suresh Babu
;
Dawit Tadesse
;
Rachael Hunter
;
Yusheng Wu
;
Jeffrey Misiaszek
;
Jared N. Cumming
;
Eric J. Gilbert
;
Chunli Huang
;
Brian A. McKittrick
;
Liwu Hong
;
Tao Guo
;
Zhaoning
Zhu
;
Corey Strickl
and
;
Peter Orth
;
Johannes H. Voigt
;
Matthew E. Kennedy
;
Xia Chen
;
Reshma Kuvelkar
;
Robert Hodgson
;
Lynn A. Hyde
;
Kathleen Cox
;
Leonard Favreau
;
Eric M. Parker
;
William J. Greenlee
刊名:ACS Medicinal Chemistry Letters
出版年:2012
6.
Discovery of Cyclic Acylguanidines as Highly Potent
and
Selective β-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I—Inhibitor Design
and
Validation
作者:
Zhaoning
Zhu
;
Zhong-Yue Sun
;
Yuanzan Ye
;
Johannes Voigt
;
Corey Strickl
and
;
Elizabeth M. Smith
;
Jared Cumming
;
Lingyan Wang
;
Jesse Wong
;
Yu-Sen Wang
;
Daniel F. Wyss
;
Xia Chen
;
Reshma Kuvelkar
;
Matthew
刊名:Journal of Medicinal Chemistry
出版年:2010
7.
Discovery of Novel Hydroxamates as Highly Potent Tumor Necrosis Factor-α Converting Enzyme Inhibitors: Part IDiscovery of Two Binding Modes
作者:
Zhaoning
Zhu
;
Robert Mazzola
;
Lisa Sinning
;
Brian McKittrick
;
Xiaoda Niu
;
Daniel Lundell
;
Jing Sun
;
Peter Orth
;
Zhu
yan Guo
;
Vincent Madison
;
Richard Ingram
;
Brian M. Beyer
刊名:Journal of Medicinal Chemistry
出版年:2008
8.
Dramatic Effects of Crystal Morphology on Solid State Reaction Course;1 Control by Crystal Disorder; Mechanistic
and
Exploratory Organic Photochemistry
作者:
Howard E. Zimmerman
;
Igor V. Alabugin
;
Wensheng Chen
;
and
Zhaoning
Zhu
刊名:Journal of the American Chemical Society
出版年:1999
9.
Ab Initio Computations of Reacting Species in Crystal Lattices; Mechanistic
and
Exploratory Organic Photochemistry
作者:
Howard E. Zimmerman
;
Pavel Sebek
;
and
Zhaoning
Zhu
刊名:Journal of the American Chemical Society
出版年:1998
10.
General Predictor for Photoreactivity in Crystal Lattices: Molecular Mechanics in Crystalline Media
and
Lock
and
Key Control. Reaction Examples
作者:
Howard E. Zimmerman
and
Zhaoning
Zhu
刊名:Journal of the American Chemical Society
出版年:1994
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