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ACS电子期刊(13)

在“ACS电子期刊”中，命中：13条，耗时：0.0200189 秒

在所有数据库中总计命中：14条

1.Design of Pyridopyrazine-1,6-dione 纬-Secretase Modulators that Align Potency, MDR Efflux Ratio, and Metabolic Stability

作者：Martin Pettersson ; Douglas S. Johnson ; John M. Humphrey ; Todd W. Butler ; Christopher W. am Ende ; Benjamin A. Fish ; Michael E. Green ; Gregory W. Kauffman ; Patrick B. Mullins ; Christopher J. O鈥橠onnell ; Antonia F. Stepan ; Cory M. Stiff ; Chakrapani Subramanyam ; Tuan P. Tran ; Beth Cooper Vetelino ; Eddie Yang ; Longfei Xie ; Kelly R. Bales ; Leslie R. Pustilnik ; Stefanus J. Steyn ; Kathleen M. Wood ; Patrick R. Verhoest

刊名：ACS Medicinal Chemistry Letters

出版年：2015

2.Discovery and Preclinical Characterization of 1-Methyl-3-(4-methylpyridin-3-yl)-6-(pyridin-2-ylmethoxy)-1H-pyrazolo-[3,4-b]pyrazine (PF470): A Highly Potent, Selective, and Efficacious M

作者：Lei Zhang ; Gayatri Balan ; Gabriela Barreiro ; Brian P. Boscoe ; Lois K. Chenard ; Julie Cianfrogna ; Michelle M. Claffey ; Laigao Chen ; Karen J. Coffman ; Susan E. Drozda ; Joshua R. Dunetz ; Kari R. Fonseca ; Paul Galatsis ; Sarah Grimwood ; John T. Lazzaro ; Jessica Y. Mancuso ; Emily L. Miller ; Matthew R. Reese ; Bruce N. Rogers ; Isao Sakurada ; Marc Skaddan ; Deborah L. Smith ; Antonia F. Stepan ; Patrick Trapa ; Jamison B. Tuttle ; Patrick R. Verhoest ; Daniel P. Walker ; Ann S. Wright ; Margaret M. Zaleska ; Kenneth Zasadny ; Christopher L. Shaffer

刊名：Journal of Medicinal Chemistry

出版年：2014

3.Evaluating the Differences in Cycloalkyl Ether Metabolism Using the Design Parameter 鈥淟ipophilic Metabolism Efficiency鈥?(LipMetE) and a Matched Molecular Pairs Analysis

作者：Antonia F. Stepan ; Gregory W. Kauffman ; Christopher E. Keefer ; Patrick R. Verhoest ; Martin Edwards

刊名：Journal of Medicinal Chemistry

出版年：2013

4.Discovery of Dap-3 Polymyxin Analogues for the Treatment of Multidrug-Resistant Gram-Negative Nosocomial Infections

作者：Thomas V. Magee ; Matthew F. Brown ; Jeremy T. Starr ; David C. Ackley ; Joseph A. Abramite ; Jiri Aubrecht ; Andrew Butler ; Jared L. Crandon ; Fadia Dib-Hajj ; Mark E. Flanagan ; Karl Granskog ; Joel R. Hardink ; Michael D. Huband ; Rebecca Irvine ; Michael Kuhn ; Karen L. Leach ; Bryan Li ; Jian Lin ; David R. Luke ; Shawn H. MacVane ; Alita A. Miller ; Sandra McCurdy ; James M. McKim ; Jr. ; David P. Nicolau ; Thuy-Trinh Nguyen ; Mark C. Noe ; John P. O鈥橠onnell ; Scott B. Seibel ; Yue Shen ; Antonia F. Stepan ; Andrew P. Tomaras ; Paul C. Wilga ; Li Zhang ; Jinfeng Xu ; Jinshan Michael Chen

刊名：Journal of Medicinal Chemistry

出版年：2013

5.Pd(II)-Catalyzed ortho- or meta-C鈥揌 Olefination of Phenol Derivatives

作者：Hui-Xiong Dai ; Gang Li ; Xing-Guo Zhang ; Antonia F. Stepan ; Jin-Quan Yu

刊名：The Journal of the American Chemical Society

出版年：2013

6.Sequential Allylic C鈥揌 Amination/Vinylic C鈥揌 Arylation: A Strategy for Unnatural Amino Acid Synthesis from 伪-Olefins

作者：Chao Jiang ; Dustin J. Covell ; Antonia F. Stepan ; Mark S. Plummer ; M. Christina White

刊名：Organic Letters

出版年：2012

7.Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active 纬-Secretase Inhibitor

作者：Antonia F. Stepan ; Chakrapani Subramanyam ; Ivan V. Efremov ; Jason K. Dutra ; Theresa J. O鈥橲ullivan ; Kenneth J. DiRico ; W. Scott McDonald ; Annie Won ; Peter H. Dorff ; Charles E. Nolan ; Stacey L. Becker ; Leslie R. Pustilnik ; David R. Riddell ; Gregory W. Kauffman ; Bethany L. Kormos ; Liming Zhang ; Yasong Lu ; Steven H. Capetta ; Michael E. Green ; Kapil Karki ; Evelyn Sibley ; Kevin P. Atchison ; Andrew J. Hallgren ; Christine E. Oborski ; Ashley E. Robshaw ; Blossom Sneed ; Christopher J. O鈥橠onnell

刊名：Journal of Medicinal Chemistry

出版年：2012

8.Divergent C鈥揌 Functionalizations Directed by Sulfonamide Pharmacophores: Late-Stage Diversification as a Tool for Drug Discovery

作者：Hui-Xiong Dai ; Antonia F. Stepan ; Mark S. Plummer ; Yang-Hui Zhang ; Jin-Quan Yu

刊名：Journal of the American Chemical Society

出版年：2011

9.Oxidative Metabolism of a Quinoxaline Derivative by Xanthine Oxidase in Rodent Plasma

作者：Raman Sharma ; Heather Eng ; Gregory S. Walker ; Gabriela Barreiro ; Antonia F. Stepan ; Kim F. McClure ; Angela Wolford ; Paul D. Bonin ; Peter Cornelius ; Amit S. Kalgutkar

刊名：Chemical Research in Toxicology

出版年：2011

10.Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top

作者：Antonia F. Stepan ; Daniel P. Walker ; Jonathan Bauman ; David A. Price ; Thomas A. Baillie ; Amit S. Kalgutkar ; Michael D. Aleo

刊名：Chemical Research in Toxicology

出版年：2011

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