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内部出版物
SpringerLink电子期刊(1)
Elsevier电子期刊(4)
ACS电子期刊(10)
在“
ACS电子期刊
”中,
命中:
10
条,耗时:小于0.01 秒
在所有数据库中总计命中:
15
条
1.
Discovery of Clinical Candidate CEP-37440, a Selective Inhibitor of Focal Adhesion Kinase (FAK) and Anaplastic Lymphoma Kinase (ALK)
作者:
Gregory R. Ott
;
Mangeng
Cheng
;
Keith S. Learn
;
Jason Wagner
;
Diane E. Gingrich
;
Joseph G. Lisko
;
Matthew Curry
;
Eugen F. Mesaros
;
Arup K. Ghose
;
Matthew R. Quail
;
Weihua Wan
;
Lihui Lu
;
Pawel Dobrzanski
;
Mark S. Albom
;
Thelma S. Angeles
;
Kevin Wells-Knecht
;
Zeqi Huang
;
Lisa D. Aimone
;
Elizabeth Bruckheimer
;
Nathan Anderson
;
Jay Friedman
;
Sandra V. Fernandez
;
Mark A. Ator
;
Bruce A. Ruggeri
;
Bruce D. Dorsey
刊名:Journal of Medicinal Chemistry
出版年:2016
2.
Discovery of Pyrophosphate Diesters as Tunable, Soluble, and Bioorthogonal Linkers for Site-Specific Antibody–Drug Conjugates
作者:
Jeffrey C. Kern
;
Mark Cancilla
;
Deborah Dooney
;
Kristen Kwasnjuk
;
Rena Zhang
;
Maribel Beaumont
;
Isabel Figueroa
;
SuChun Hsieh
;
Linda Liang
;
Daniela Tomazela
;
Jeffrey Zhang
;
Philip E. Brandish
;
Anthony Palmieri
;
Peter Stivers
;
Mangeng
Cheng
;
Guo Feng
;
Prasanthi Geda
;
Sanjiv Shah
;
Andrew Beck
;
Damien Bresson
;
Juhi Firdos
;
Dennis Gately
;
Nick Knudsen
;
Anthony Manibusan
;
Peter G. Schultz
;
Ying Sun
;
Robert M. Garbaccio
刊名:Journal of the American Chemical Society
出版年:2016
3.
Novel Phosphate Modified Cathepsin B Linkers: Improving Aqueous Solubility and Enhancing Payload Scope of ADCs
作者:
Jeffrey C. Kern
;
Deborah Dooney
;
Rena Zhang
;
Linda Liang
;
Philip E. Brandish
;
Mangeng
Cheng
;
Guo Feng
;
Andrew Beck
;
Damien Bresson
;
Juhi Firdos
;
Dennis Gately
;
Nick Knudsen
;
Anthony Manibusan
;
Ying Sun
;
Robert M. Garbaccio
刊名:Bioconjugate Chemistry
出版年:2016
4.
Design, Synthesis, and Anaplastic Lymphoma Kinase (ALK) Inhibitory Activity for a Novel Series of 2,4,8,22-Tetraazatetracyclo[14.3.1.13,7.19,13]docosa-1(20),3(22),4,6,9(21),10,12
作者:
Henry J. Breslin
;
Brandon M. Lane
;
Gregory R. Ott
;
Arup K. Ghose
;
Thelma S. Angeles
;
Mark S. Albom
;
Mangeng
Cheng
;
Weihua Wan
;
R. Curtis Haltiwanger
;
Kevin J. Wells-Knecht
;
Bruce D. Dorsey
刊名:Journal of Medicinal Chemistry
出版年:2012
5.
Strategies to Mitigate the Bioactivation of 2-Anilino-7-Aryl-Pyrrolo[2,1-f][1,2,4]triazines: Identification of Orally Bioavailable, Efficacious ALK Inhibitors
作者:
Eugen F. Mesaros
;
Tho V. Thieu
;
Gregory J. Wells
;
Craig A. Zificsak
;
Jason C. Wagner
;
Henry J. Breslin
;
Rabindranath Tripathy
;
James L. Diebold
;
Robert J. McHugh
;
Ashley T. Wohler
;
Matthew R. Quail
;
Weihua Wan
;
Lihui Lu
;
Zeqi Huang
;
Mark S. Albom
;
Thelma S. Angeles
;
Kevin J. Wells-Knecht
;
Lisa D. Aimone
;
Mangeng
Cheng
;
Mark A. Ator
;
Gregory R. Ott
;
Bruce D. Dorsey
刊名:Journal of Medicinal Chemistry
出版年:2012
6.
Discovery of an Orally Efficacious Inhibitor of Anaplastic Lymphoma Kinase
作者:
Diane E. Gingrich
;
Joseph G. Lisko
;
Matthew A. Curry
;
Mangeng
Cheng
;
Matthew Quail
;
Lihui Lu
;
Weihua Wan
;
Mark S. Albom
;
Thelma S. Angeles
;
Lisa D. Aimone
;
R. Curtis Haltiwanger
;
Kevin Wells-Knecht
;
Gregory R. Ott
;
Arup K. Ghose
;
Mark A. Ator
;
Bruce Ruggeri
;
Bruce D. Dorsey
刊名:Journal of Medicinal Chemistry
出版年:2012
7.
2,7-Disubstituted-pyrrolo[2,1-f][1,2,4]triazines: New Variant of an Old Template and Application to the Discovery of Anaplastic Lymphoma Kinase (ALK) Inhibitors with in Vivo Antitumor Activity
作者:
Gregory R. Ott
;
Gregory J. Wells
;
Tho V. Thieu
;
Matthew R. Quail
;
Joseph G. Lisko
;
Eugen F. Mesaros
;
Diane E. Gingrich
;
Arup K. Ghose
;
Weihua Wan
;
Lihui Lu
;
Mangeng
Cheng
;
Mark S. Albom
;
Thelma S. Angeles
;
Zeqi Huang
;
Lisa D. Aimone
;
Mark A. Ator
;
Bruce A. Ruggeri
;
Bruce D. Dorsey
刊名:Journal of Medicinal Chemistry
出版年:2011
8.
2,7-Disubstituted-Pyrrolotriazine Kinase Inhibitors with an Unusually High Degree of Reactive Metabolite Formation
作者:
Kevin J. Wells-Knecht
;
Gregory R. Ott
;
Mangeng
Cheng
;
Gregory J. Wells
;
Henry J. Breslin
;
Diane E. Gingrich
;
Linda Weinberg
;
Eugen F. Mesaros
;
Zeqi Huang
;
Mehran Yazdanian
;
Mark A. Ator
;
Lisa D. Aimone
;
Kelli Zeigler
;
Bruce D. Dorsey
刊名:Chemical Research in Toxicology
出版年:2011
9.
ALK Mutants in the Kinase Domain Exhibit Altered Kinase Activity and Differential Sensitivity to Small Molecule ALK Inhibitors
作者:
Lihui Lu
;
Arup K. Ghose
;
Matthew R. Quail
;
Mark S. Albom
;
John T. Durkin
;
Beverly P. Holskin
;
Thelma S. Angeles
;
Sheryl L. Meyer
;
Bruce A. Ruggeri
;
Mangeng
Cheng
刊名:Biochemistry
出版年:2009
10.
Preparation of Steroid Antibodies and Parallel Detection of Multianabolic Steroid Abuse with Conjugated Hapten Microarray
作者:
Hongwu Du
;
Yuan Lu
;
Weiping Yang
;
Moutian Wu
;
Jun Wang
;
Shan Zhao
;
Mangeng
Pan
;
and Jing
Cheng
刊名:Analytical Chemistry
出版年:2004
1
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