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Elsevier电子期刊(28)

在“Elsevier电子期刊”中，命中：28条，耗时：小于0.01 秒

在所有数据库中总计命中：28条

1.Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication

作者：Nicky Helsen¹ ; ^&dagger ; ; ^{nicky.helsen@med.kuleuven.be" class="auth_mail" title="E-mail the corresponding author} ; Yannick Debing² ; ^&dagger ; ; Jan Paeshuyse² ; Kai Dallmeier² ; Ruben Boon¹ ; Mar Coll³ ; Pau Sancho-Bru³ ; Christel Claes¹ ; Johan Neyts² ; ^&Dagger ; ; Catherine M. Verfaillie¹ ; ^&Dagger ;

关键词：(+)ssRNA ; positive strand RNA ; (&minus ; )ssRNA ; negative strand RNA ; αSMA ; alpha smooth muscle actin ; AAT ; alpha 1-antitrypsin ; AFP ; alpha fetoprotein ; BLBP ; brain lipid-binding protein ; BMP4 ; bone morphogenetic protein 4 ; COL1A1 ; collagen type 1 alpha 1 ; DLX2 ; distal-less homeobox 2 ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; FBS ; fetal bovine serum ; FGF ; fibroblast growth factor ; FISH ; fluorescence in situ hybridization ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; hESC ; human em

刊名：Journal of Hepatology

出版年：2016

2.Comparative analysis of the anti-chikungunya virus activity of novel bryostatin analogs confirms the existence of a PKC-independent mechanism

作者：Rana Abdelnabi^a ; Daryl Staveness^b ; Katherine E. Near^b ; Paul A. Wender^b ; Leen Delang^a ; Johan Neyts^a ; ^{Johan.Neyts@rega.kuleuven.be" class="auth_mail" title="E-mail the corresponding author} ; Pieter Leyssen^a

关键词：Chikungunya virus ; Bryostatin ; Protein kinase C ; Sotrastaurin ; Salicylate

刊名：Biochemical Pharmacology

出版年：2016

3.Assessment of the activity of directly acting antivirals and other products against different genotypes of hepatitis C virus prevalent in resource-poor countries

作者：Hayat Khan^a ; ^b ; Jan Paeshuyse^a ; Sheeba Murad^b ; Johan Neyts^a ; ^{johan.neyts@rega.kuleuven.be" class="auth_mail" title="E-mail the corresponding author}

关键词：Hepatitis C virus ; Direct acting antivirals ; Food additives ; Subgenomic replicons

刊名：Antiviral Research

出版年：2016

4.VP1 crystal structure-guided exploration and optimization of 4,5-dimethoxybenzene-based inhibitors of rhinovirus 14 infection

作者：Laurè ; ne Da Costa^a ; Manon Roche^a ; Els Scheers^b ; Antonio Coluccia^c ; Johan Neyts^b ; ^{johan.neyts@rega.kuleuven.be" class="auth_mail" title="E-mail the corresponding author} ; Thierry Terme^a ; Pieter Leyssen^b ; Romano Silvestri^c ; ^{romano.silvestri@uniroma1.it" class="auth_mail" title="E-mail the corresponding author} ; Patrice Vanelle^a ; ^{patrice.vanelle@univ-amu.fr" class="auth_mail" title="E-mail the corresponding author}

关键词：VP1 protein ; HRV14 ; Capsid inhibitors ; In silico design ; TDAE

刊名：European Journal of Medicinal Chemistry

出版年：2016

5.3-(imidazo[1,2-a:5,4-b′]dipyridin-2-yl)aniline inhibits pestivirus replication by targeting a hot spot drug binding pocket in the RNA-dependent RNA polymerase

作者：Simone Musiu^a ; Pieter Leyssen^a ; Mathy Froeyen^b ; Jean-Michel Chezal^d ; ^e ; Johan Neyts^a ; ^{Johan.Neyts@rega.kuleuven.be" class="auth_mail" title="E-mail the corresponding author} ; Jan Paeshuyse^a ; ^c

关键词：Bovine viral diarrhea virus ; RNA-dependent RNA polymerase ; 3-(imidazo[1 ; 2-a5 ; 4-b&prime ; ]dipyridin-2-yl)aniline

刊名：Antiviral Research

出版年：2016

6.Hepatitis E virus mutations associated with ribavirin treatment failure result in altered viral fitness and ribavirin sensitivity

作者：Yannick Debing¹ ; ^&dagger ; ; Christophe Ramiè ; re² ; ³ ; ⁴ ; ⁵ ; ^&dagger ; ; Kai Dallmeier¹ ; Gé ; raldine Piorkowski⁶ ; Mary-Anne Trabaud² ; Fanny Lebossé ; ⁴ ; ⁵ ; ⁷ ; ⁸ ; Caroline Scholtè ; s² ; ³ ; ⁴ ; ⁵ ; Magali Roche⁹ ; Catherine Legras-Lachuer⁹ ; ¹⁰ ; Xavier de Lamballerie⁶ ; ¹¹ ; Patrice André ; ² ; ³ ; ⁴ ; ⁵ ; ^&Dagger ; ; Johan Neyts¹ ; ^&Dagger ; ; ^{johan.neyts@rega.kuleuven.be" class="auth_mail" title="E-mail the corresponding author}

关键词：HEV ; hepatitis E virus ; RBV ; ribavirin ; ALT ; alanine aminotransferase ; IU ; international units ; γGT ; γ-glutamyltransferase ; CLL ; chronic lymphoid leukemia ; NGS ; next-generation sequencing ; RdRp ; RNA-dependent RNA polymerase ; HVR ; hypervariable region ; ORF ; open reading frame ; IMPDH ; inosine 5&prime ; -monophosphate dehydrogenase ; MPA ; mycophenolic acid ; LOD ; limit of detection ; RLU ; relative light units ; FBS ; fetal bovine serum ; HS ; human serum ; WT ; wild-type ; VC ; virus control

刊名：Journal of Hepatology

出版年：2016

7.A Mutation in the Hepatitis E Virus RNA Polymerase Promotes Its Replication and Associates With Ribavirin Treatment Failure in Organ Transplant Recipients

作者：Yannick Debing¹ ; ^&lowast ; ; Anett Gisa² ; ^&lowast ; ; Kai Dallmeier¹ ; Sven Pischke³ ; Birgit Bremer² ; Michael Manns² ; Heiner Wedemeyer² ; ^§ ; ; Pothakamuri Venkata Suneetha² ; ^§ ; ; Johan Neyts¹ ; ^{johan.neyts@rega.kuleuven.be" class="auth_mail" title="E-mail the corresponding author}

关键词：RNA-Dependent RNA Polymerase ; Virulence ; Drug Resistant ; Mechanism

刊名：Gastroenterology

出版年：2014

8.Are statins a viable option for the treatment of infections with the hepatitis C virus?

作者：Ben Verpaalen ; Johan Neyts ; ^{johan.neyts@rega.kuleuven.be" class="auth_mail} ; Leen Delang

关键词：Statins ; Hepatitis C virus (HCV) ; Antiviral therapy ; Host-targeting antivirals ; Combination therapy ; Cholesterol

刊名：Antiviral Research

出版年：May, 2014

9.Substituted 2,6-bis(benzimidazol-2-yl)pyridines: A novel chemical class of pestivirus inhibitors that targets a hot spot for inhibition of pestivirus replication in the RNA-dependent RNA polymerase

作者：Simone Musiu^a ; Gerhard Pü ; rstinger^b ; Sylvia Stallinger^b ; Robert Vrancken^c ; ¹ ; Andy Haegeman^c ; Frank Koenen^c ; Pieter Leyssen^a ; Mathy Froeyen^a ; Johan Neyts^a ; ^{Johan.Neyts@rega.kuleuven.be" class="auth_mail} ; Jan Paeshuyse^a

关键词：Bovine viral diarrhea virus ; RNA-dependent RNA polymerase ; Substituted 2 ; 6-bis(benzimidazol-2-yl)pyridine inhibitors

刊名：Antiviral Research

出版年：June 2014

10.Synthesis, biological activity and structure-activity relationship of 4,5-dimethoxybenzene derivatives inhibitor of rhinovirus 14 infection

作者：Manon Roche^a ; Cé ; line Lacroix^b ; Omar Khoumeri^a ; David Franco^b ; Johan Neyts^b ; ^{johan.neyts@rega.kuleuven.be" class="auth_mail} ; Thierry Terme^a ; Pieter Leyssen^b ; Patrice Vanelle^a ; ^{patrice.vanelle@univ-amu.fr" class="auth_mail}

关键词：Human rhinovirus 14 ; Tetrakis(DimethylAmino)Ethylene ; 4 ; 5-Dimethoxybenzenes ; Antiviral activity

刊名：European Journal of Medicinal Chemistry

出版年：9 April, 2014

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