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Elsevier电子期刊(80)

在“Elsevier电子期刊”中，命中：80条，耗时：0.0449791 秒

在所有数据库中总计命中：144条

1.Topically Applied Hsp90 Blocker 17AAG Inhibits Autoantibody-Mediated Blister-Inducing Cutaneous Inflammation

作者：Stefan Tukaj¹ ; ² ; ⁵ ; Katja Bieber³ ; ⁵ ; Konrad Kleszczyński¹ ; Mareike Witte¹ ; Rebecca Cames¹ ; Kathrin Kalies⁴ ; Detlef Zillikens¹ ; ³ ; Ralf J. Ludwig¹ ; ³ ; Tobias W. Fischer¹ ; Michael Kasperkiewicz¹ ; ^{Michael.Kasperkiewicz@uksh.de}

关键词：17AAG ; 17-allylamino-demethoxygeldanamycin ; COL7 ; type VII collagen ; EBA ; epidermolysis bullosa acquisita ; MMP ; matrix metalloproteinase ; PBS ; phosphate buffered saline ; qRT-PCR ; quantitative real-time reverse transcriptase-PCR ; RT ; room temperature

刊名：Journal of Investigative Dermatology

出版年：2017

2.Inhibition of heat shock protein (Hsp) 90 potentiates the antiproliferative and pro-apoptotic effects of 2-(4′fluoro-phenylamino)-4H-1,3-thiazine[6,5-b]indole in A2780cis cells

作者：Zuzana Solá ; rová ; ^a ; Martin Kello^a ; Lenka Varinská ; ^a ; Mariana Budovská ; ^b ; Peter Solá ; r^c ; ^{peter.solar@upjs.sk}

关键词：thiazine[6 ; 5-b]indole ; 2-(4&prime ; fluoro-phenylamino)-4H-1 ; 3-thiazine[6 ; 5-b]indole ; Hsp ; heat shock protein ; 17-DMAG ; 17-dimethylaminoethylamino-17-demethoxygeldanamycin ; 17-AAG ; 17-(allylamino)-17-demethoxygeldanamycin ; A2780 ; human ovarian adenocarcinoma cell line ; A2780cis ; human ovarian adenocarcinoma cell line resistant to cisplatin ; PARP ; poly (ADP-ribose) polymerase ; MMP ; mitochondrial membrane potential ; An ; annexin ; PI ; propidium iodide

刊名：Biomedicine & Pharmacotherapy

出版年：2017

3.Virtual screening and biophysical studies lead to HSP90 inhibitors

作者：Renjie Huang ; Daniel M. Ayine-Tora ; M. Nasri Muhammad Rosdi ; Yu Li ; Jó ; hannes Reynisson ; ^{j.reynisson@auckland.ac.nz} ; Ivanhoe K.H. Leung ; ^{i.leung@auckland.ac.nz}

关键词：17-AAG ; 17-allylamino-17-demethoxygeldanamycin ; 17-DMAG ; 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG) ; ADP ; adenosine diphosphate ; AMPPCP ; 5&prime ; -adenylylmethylenediphosphonate ; ASP ; Astex statistical potential ; ATP ; adenosine triphosphate ; CS ; ChemScore ; GS ; GoldScore ; HB ; hydrogen bonding ; HSP90 ; heat shock protein 90 ; HSQC ; heteronuclear single quantum correlation ; KD ; binding affinity ; ND ; N-domain ; NMR ; nuclear magnetic resonance ; NOE ; nuclear Overhauser effect ; Tm ; pro

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

4.Epothilone B-based 3-in-1 polymeric micelle for anticancer drug therapy

作者：Dae Hwan Shin ; Glen S. Kwon ; ^{gskwon@pharmacy.wisc.edu}

关键词：Epothilone B ; Polymeric micelle ; Non-small cell lung cancer ; Drug combination ; Multiple drug solubilization

刊名：International Journal of Pharmaceutics

出版年：2017

5.The heat shock protein 90 inhibitor, 17-AAG, attenuates thioacetamide induced liver fibrosis in mice

作者：Nashwa M. Abu-Elsaad^a ; ^{nosha.samaa@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Marwa S. Serrya^a ; ^{marwa.sereya@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Amr M. El-Karef^b ; ^{aelkaref@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Tarek M. Ibrahim^a ; ^{tarekmoss@yahoo.com" class="auth_mail" title="E-mail the corresponding author}

关键词：17-AAG ; 17-N-Allylamino-17-demethoxygeldanamycin ; Col1A1 ; collagen-1-alpha1 ; GSH ; reduced glutathione ; HSC ; hepatic stellate cells ; Hsp ; heat shock protein ; SMA ; smooth muscle actin ; TIMP ; tissue inhibitor metalloproteinase

刊名：Pharmacological Reports

出版年：2016

6.Modulation of heat shock protein 90 affects TGF-β-induced collagen synthesis in human dermal fibroblast cells

作者：Sae Bin Lee^a ; ^b ; A-ram Lim^c ; Dong Kyun Rah^b ; Kyung Soo Kim^d ; Hyun Jin Min^d ; ^{jjinient@gmail.com}

关键词：Heat shock protein 90 (Hsp 90) ; Transforming growth factor (TGF)-β ; Collagen ; 17-N-Allylamino-17-demethoxygeldanamycin (17AAG) ; Smad 2/3

刊名：Tissue and Cell

出版年：2016

7.Linking HSP90 target occupancy to HSP70 induction and efficacy in mouse brain

作者：Kenneth Thirstrup^a ; ^{keth@lundbeck.com" class="auth_mail" title="E-mail the corresponding author} ; Florence Sotty^a ; Liliana Christina Pereira Montezinho^a ; ¹ ; Lassina Badolo^b ; Annemette Thougaard^c ; Maj Kristjá ; nsson^d ; Thomas Jensen^e ; Stephen Watson^e ; Sø ; ren Mø ; ller Nielsen^d

关键词：17-AAG ; 17-Allylamino-17-demethoxygeldanamycin ; Cmpd ; compound ; CNS ; central nervous system ; fEPSP ; evoked postsynaptic field potential ; HSF1 ; heat-shock factor 1 ; HSP ; heat-shock protein ; Occ50 ; 50% occupancy ; p.o. ; peroral dosing

刊名：Pharmacological Research

出版年：2016

8.Dual mode of cancer cell destruction for pancreatic cancer therapy using Hsp90 inhibitor loaded polymeric nano magnetic formulation

作者：Ankit K. Rochani ; Sivakumar Balasubramanian ; Aswathy Ravindran Girija ; Sreejith Raveendran ; Ankita Borah ; Yutaka Nagaoka ; Yoshikata Nakajima ; Toru Maekawa ; D. Sakthi Kumar ; ^{sakthi@toyo.jp" class="auth_mail" title="E-mail the corresponding author} ; ^{drsakthi@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Nanotechnology ; Cancer chemotherapy ; Hsp90 inhibitor ; Nano formulation ; 17AAG

刊名：International Journal of Pharmaceutics

出版年：2016

9.Jump in the fire — heat shock proteins and their impact on ovarian cancer therapy

作者：M.B. Stope^a ; ^{matthias.stope@uni-greifswald.de" class="auth_mail" title="E-mail the corresponding author}Author Vitae ; D. Koensgen^b ; M. Burchardt^a ; N. Concin^c ; M. Zygmunt^b ; A. Mustea^b

关键词：OC ; ovarian cancer ; HSP ; heat shock proteins ; 17-AAG ; 17-allylamino-demethoxygeldanamycin

刊名：Critical Reviews in Oncology and Hematology

出版年：2016

10.BIIB021, a synthetic Hsp90 inhibitor, induces mutant ataxin-1 degradation through the activation of heat shock factor 1

作者：Ying Ding^a ; Hiroaki Adachi^a ; ^b ; Masahisa Katsuno^a ; Kentaro Sahashi^a ; Naohide Kondo^a ; Madoka Iida^a ; Genki Tohnai^a ; Hideaki Nakatsuji^a ; Gen Sobue^a ; ^c ; ^{sobueg@med.nagoya-u.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：17-AAG ; 17-allylamino-17-demethoxygeldanamycin ; ALP ; autophagy-lysosome pathway ; AR ; androgen receptor ; ATXN1 ; ataxin-1 ; DMSO ; dimethyl sulfoxide ; DRPLA ; dentatorubral pallidoluysian atrophy ; HD ; Huntington&rsquo ; s disease ; HSE ; heat shock element ; HSF1 ; heat shock factor 1 ; HSP ; heat shock proteins ; Hsp90 ; heat shock protein 90 ; N2a ; Neuro2a ; polyQ ; polyglutamine ; RT-PCR ; reverse transcription PCR ; SBMA ; spinal and bulbar muscular atrophy ; SCA1 ; spinocerebellar ataxia type 1 ; UPS ; ubiquitin-pro

刊名：Neuroscience

出版年：2016

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