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在“
Elsevier电子期刊
”中,
命中:
3,680
条,耗时:0.06097 秒
在所有数据库中总计命中:
4,513
条
1.
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as
5
-
HT
7
and
5
-HT
1A
receptor
ligands: Synthesis, structure-activity relationships, and molecular modeling studies
作者:
Sebastiano Intagliata
a
;
1
;
s.intagliata@studium.unict.it
;
Maria N. Modica
a
;
1
;
Valeria Pittalà
;
a
;
Loredana Salerno
a
;
Maria A. Siracusa
a
;
Alfredo Cagnotto
b
;
Mario Salmona
b
;
Rafał Kurczab
c
;
Giuseppe Romeo
a
关键词:
5
-
HT
7
receptor
ligands
;
5
-
HT1A
receptor
ligands
;
Long-chain arylpiperazines
;
Molecular modeling
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
2.
The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for
5
-
HT
1A
receptor
over α
1
-adrenoceptor and D
2
-like
receptor
subtypes
作者:
Fabio Del Bello
a
;
1
;
Alessandro Bonifazi
a
;
b
;
1
;
Mario Giannella
a
;
Gianfabio Giorgioni
a
;
Alessandro Piergentili
a
;
Riccardo Petrelli
a
;
Carlo Cifani
a
;
Maria Vittoria Micioni Di Bonaventura
a
;
Thomas M. Keck
b
;
c
;
d
;
Angelica Mazzolari
e
;
Giulio Vistoli
e
;
Antonio Cilia
f
;
Elena Poggesi
f
;
Rosanna Matucci
g
;
Wilma Quaglia
a
;
wilma.quaglia@unicam.it
关键词:
5
-
HT1A
receptor
;
α1-Adrenoceptor subtypes
;
D2-like
receptor
subtypes
;
Selective
5
-
HT1A
receptor
agonists
;
Docking studies
;
Anxiolytic effect
刊名:European Journal of Medicinal Chemistry
出版年:2017
3.
Crohn's disease-associated mucosal factors regulate the expression of TNF-like cytokine
1A
and its
receptor
s in primary subepithelial intestinal myofibroblasts and intestinal epithelial cells
作者:
Giorgos Bamias
a
;
gbamias@gmail.com
;
Eirini Filidou
b
;
Dimitris Goukos
c
;
Vasilis Valatas
d
;
Konstantinos Arvanitidis
b
;
Maria Panagopoulou
b
;
Georgios Kouklakis
e
;
George L. Daikos
c
;
Spiros D. Ladas
a
;
George Kolios
b
关键词:
TL
1A
;
TNF-like cytokine
1A
;
DR3
;
death-domain
receptor
3
;
DcR3
;
decoy
receptor
3
;
CD
;
Crohn's disease
;
SEMFs
;
subepithelial myofibroblasts
刊名:Translational Research
出版年:2017
4.
Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.
5
]decane derivatives as potent and selective
5
-
HT
1A
receptor
agonists
作者:
Silvia Franchini
a
;
Leda Ivanova Manasieva
a
;
Claudia Sorbi
a
;
Umberto M. Battisti
a
;
Paola Fossa
b
;
Elena Cichero
b
;
Nunzio Denora
c
;
Rosa Maria Iacobazzi
c
;
d
;
Antonio Cilia
e
;
Lorenza Pirona
e
;
Simone Ronsisvalle
f
;
Giuseppina Aricò
;
f
;
Livio Brasili
a
;
livio.brasili@unimore.it
关键词:
5
-
HT1A
receptor
;
Agonist
;
Neuroprotection
;
BBB penetration
;
Analgesic activity
刊名:European Journal of Medicinal Chemistry
出版年:2017
5.
Serotonin Signaling through Prefrontal Cortex
5
-
HT
1A
Receptor
s during Adolescence Can Determine Baseline Mood-Related Behaviors
作者:
Alvaro L. Garcia-Garcia
1
;
Qingyuan Meng
1
;
Sarah Canetta
2
;
Alain M. Gardier
3
;
Bruno P. Guiard
3
;
Christoph Kellendonk
2
;
4
;
5
;
Alex Dranovsky
1
;
ad722@cumc.columbia.edu
;
E. David Leonardo
1
;
6
;
el367@cumc.columbia.edu
关键词:
serotonin
;
5
-
HT1A
;
depression
;
anxiety
;
development
;
adolescence
;
mPFC
;
DRN
刊名:Cell Reports
出版年:2017
6.
Design and synthesis of novel N-sulfonyl-2-indoles that behave as
5
-
HT
6
receptor
ligands with significant selectivity for D
3
over D
2
receptor
s
作者:
Oscar M. Saavedra
a
;
Delphine Karila
a
;
Dominique Brossard
a
;
Anne Rojas
b
;
Delphine Dupuis
c
;
Arnaud Gohier
d
;
Clotilde Mannoury la Cour
c
;
Mark J. Millan
c
;
;
Jean-Claude Ortuno
b
;
;
Stephen Hanessian
a
;
关键词:
Benzocyclobutane
;
Indole
;
CNS
receptor
s
;
Schizophrenia
;
Antipsychotic
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
7.
Involvement of presynaptic
5
-
HT
1A
receptor
s in the low propensity of brexpiprazole to induce extrapyramidal side effects in rats
作者:
Cedric Mombereau
a
;
CMOM@lundbeck.com
;
Jø
;
rn Arnt
b
;
Arne Mø
;
rk
a
关键词:
ANOVA
;
Analysis of variance
;
DA
;
Dopamine
;
EPS
;
Extrapyramidal side effects
;
l-DOPA
;
l-3
;
4-dihydroxyphenylalanine
;
mPFC
;
Medial prefrontal cortex
;
5
-
HT
;
Serotonin
刊名:Pharmacology Biochemistry and Behavior
出版年:2017
8.
5
-
HT1A
receptor
(HTR1A)
5
′ region haplotypes significantly affect protein expression in vitro
作者:
Xue Wu
;
Jun Yao
;
Mei Ding
;
Zhang-sen Shi
;
Feng-ling Xu
;
Jing-jing Zhang
;
Bao-jie Wang
;
wangbj77@163.com
关键词:
HT
R
1A
;
Polymorphism
;
Promoter
;
Transcription
;
Schizophrenia
刊名:Neuroscience Letters
出版年:2017
9.
The
5
-
HT
1A
/1B
-
receptor
agonist eltoprazine increases both catecholamine release in the prefrontal cortex and dopamine release in the nucleus accumbens and decreases motivation for reward and “waiting” impulsivity, but increases “stopping” impulsivity
作者:
S. Mechiel Korte
a
;
d
;
s.m.korte@uu.nl
;
Jolanda Prins
a
;
Filip S. Van den Bergh
a
;
Ronald S. Oosting
a
;
Rudy Dupree
a
;
Gerdien A.H. Korte-Bouws
a
;
Koen G.C. Westphal
a
;
Berend Olivier
b
;
Damiaan A. Denys
c
;
Alexis Garland
d
;
Onur Gü
;
ntü
;
rkü
;
n
d
关键词:
Eltoprazine (PubChem CID
;
6
5
8
5
3)
刊名:European Journal of Pharmacology
出版年:2017
10.
Serotonin and urocortin 1 in the dorsal raphe and Edinger-Westphal nuclei after early life stress in serotonin transporter knockout rats
作者:
Rick H.A. van der Doelen
a
;
b
;
Berit Robroch
b
;
Ilse A. Arnoldussen
a
;
Maya Schulpen
a
;
Judith R. Homberg
b
;
&dagger
;
;
Tamá
;
s Kozicz
a
;
c
;
&dagger
;
;
Tamas.Kozicz@radboudumc.nl
关键词:
5
-
HT
;
5
-hydroxytryptamine
;
serotonin
;
5
-
HT1A
;
5
-
HT
receptor
1A
;
5
-
HT
T
;
5
-
HT
transporter
;
5
-
HT
TLPR
;
5
-
HT
transporter-linked polymorphic region
;
CpG
;
cytosine-phosphate-guanine
;
CRE
;
cyclic-AMP response element
;
CRF
;
corticotropin-releasing factor
;
CRF1R
;
corticotropin-releasing factor
receptor
1
;
CRF2R
;
corticotropin-releasing factor
receptor
2
;
DR
;
dorsal raphe
;
DRD
;
DR dorsal part
;
DRLW
;
DR lateral wings
;
DRV
;
DR ventral part
;
ELS
;
early life stress
;
EWcp
;
Edinger&ndash
;
Westphal centrally proje
刊名:Neuroscience
出版年:2017
1
2
3
4
5
6
7
8
9
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