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内部出版物
SpringerLink电子期刊(2)
Elsevier电子期刊(8)
在“
Elsevier电子期刊
”中,
命中:
8
条,耗时:小于0.01 秒
在所有数据库中总计命中:
10
条
1.
Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument
作者:
Pascal Furet
;
pascal.furet@novartis.com" class="auth_mail" title="E-mail the corresponding author
;
Keiichi Masuya
;
Joerg Kallen
;
Thé
;
rè
;
se Stachyra-Valat
;
Stephan Ruetz
;
Vito Guagnano
;
Philipp Holzer
;
Robert Mah
;
Stefan Stutz
;
Andrea Vaupel
;
Patrick Chè
;
ne
;
Sé
;
bastien Jeay
;
Achim
Schlapbach
关键词:
p53&ndash
;
MDM2 inhibitors
;
Protein&ndash
;
protein interaction inhibitors
;
Anticancer agents
;
Structure-based design
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
2.
Novel 3-aminopyrazole inhibitors of MK-2 discovered by scaffold hopping strategy
作者:
Juraj Velcicky
;
Rol
;
Feifel
;
Stuart Hawtin
;
Richard Heng
;
Christine Huppertz
;
Guido Koch
;
Markus Kroemer
;
Henrik Moebitz
;
Laszlo Revesz
;
Clemens Scheufler
;
Achim
Schlapbach
关键词:
MK2
;
TNFα
;
-inhibition
;
3-Aminopyrazole
;
Scaffold hopping
;
Induced-fit
;
X-ray
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
3.
In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part II
作者:
Laszlo Revesz
;
Achim
Schlapbach
;
Reiner Aichholz
;
Janet Dawson
;
Rol
;
Feifel
;
Stuart Hawtin
;
Am
;
a Littlewood-Evans
;
Guido Koch
;
Markus Kroemer
;
Henrik Mö
;
bitz
;
Clemens Scheufler
;
Juraj Velcicky
;
Ch
关键词:
MAPKAP-K2
;
MK2
;
TNFα
;
Inhibition
;
Antiinflammatory
;
In vivo
;
Rheumatoid arthritis
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
4.
In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part I
作者:
Laszlo Revesz
;
Achim
Schlapbach
;
Reiner Aichholz
;
Rol
;
Feifel
;
Stuart Hawtin
;
Richard Heng
;
Peter Hiest
;
Wolfgang Jahnke
;
Guido Koch
;
Markus Kroemer
;
Henrik Mö
;
bitz
;
Clemens Scheufler
;
Juraj Velc
关键词:
MAPKAP-K2
;
MK2
;
TNFa
;
Inhibition
;
Antiinflammatory
;
In vivo
;
Rheumatoid arthritis
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
5.
Pyrrolo-pyrimidones: A novel class of MK2 inhibitors with potent cellular activity
作者:
Achim
Schlapbach
;
Rol
;
Feifel
;
Stuart Hawtin
;
Richard Heng
;
Guido Koch
;
Henrik Moebitz
;
Laszlo Revesz
;
Clemens Scheufler
;
Juraj Velcicky
;
Rudolf Waelchli
;
Christine Huppertz
关键词:
MK2
;
MAPKAPK-2
;
TNFα
;
inhibition
;
Inflammation
;
Rheumatoid arthritis
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2008
6.
Design and preparation of 2-benzamido-pyrimidines as inhibitors of IKK
作者:
Rudolf Waelchli
;
Birgit Bollbuck
;
Christian Bruns
;
Thomas Buhl
;
Jö
;
rg Eder
;
Roland Feifel
;
Rene Hersperger
;
Philipp Janser
;
Laszlo Revesz
;
Hans-Gü
;
nter Zerwes and
Achim
Schlapbach
关键词:
2-Benzamido-pyrimidines
;
IKK inhibitors
;
IKK2
;
In vivo activity
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2006
7.
A novel Pd-catalyzed cyclization reaction of ureas for the synthesis of dihydroquinazolinone p38 kinase inhibitors
作者:
Schlapbach
;
Achim
;
Heng
;
Richard
;
Di Padova
;
Franco
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2004
8.
A general palladium-catalysed synthesis of aromatic and heteroaromatic thioethers
作者:
Schopfer
;
Ulrich
;
Schlapbach
;
Achim
关键词:
diaryl thioethers
;
palladium
;
cross-coupling
;
homogeneous catalysis
;
heterocycles
刊名:Tetrahedron
出版年:2001
1
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